DOK5 and CCDC85B

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		DOK5	CCDC85B
Gene Name		docking protein 5	coiled-coil domain containing 85B
Image			No pdb structure
Gene Ontology Annotations	Cellular Component		Nucleus Cytoplasm Centrosome
	Molecular Function	Receptor Signaling Protein Activity Insulin Receptor Binding	Protein Binding
	Biological Process	MAPK Cascade Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Nervous System Development	Transcription, DNA-templated Cell Differentiation Negative Regulation Of Cell Growth Negative Regulation Of Fat Cell Differentiation Negative Regulation Of Transcription, DNA-templated
Pathways
Drugs
Diseases
GWAS		Functional MRI ( 20215924)
Protein-Protein Interactions		9 interactors: BNIP3L CCDC85B EGFR IGF1R INSR NTRK2 NTRK3 OPRM1 RET	133 interactors: AGGF1 AKAP17A AKIRIN2 ALS2CR11 APEX2 AQP1 BEX2 C10orf10 C19orf25 C1orf111 C20orf195 C21orf91 C7orf50 C8orf48 CARD9 CCDC112 CCDC116 CCDC120 CCDC185 CCDC33 CCDC67 CCNK CDK18 CDKN1A CEP70 CFAP53 CHCHD3 COPS4 CWC25 DOK5 DTNB DUSP13 EIF3H ENKD1 EPS8 EXOC7 EXOC8 EZH2 FAM107A FAM124B FAM13C FAM208B FAM214B FAM27E3 FAM50B FAM74A4 FASTKD5 FBF1 FCHSD2 FXR2 GCC1 GFI1B GPANK1 HMG20B HNRNPC IKZF5 KANSL1 KIAA0408 KRT17 KRT18 KRT20 KRT6A LDOC1 LMO3 LNX1 LZTS2 MBIP MCM10 MCRS1 MEAF6 MOAP1 MOB1A MOB4 NDUFA5 NEK6 NGFRAP1 NIF3L1 NRIP1 NUP54 PBXIP1 PIDD1 PKN1 PLEKHF2 PLOD3 POLR2L PRC1 PRPF3 PSMA1 PSMC1 PSMC6 PSMF1 RALYL RBM41 RBM7 RIBC2 RNF8 SCNM1 SETD5 SF3A3 SIX1 SLU7 SMARCD1 SYT17 SYTL4 TCEANC TCHP TEAD4 THAP7 TNNI1 TNNT1 TSPYL4 TTC14 TTC25 TUBGCP4 USP2 UTP14A UTP6 VPS72 ZBTB16 ZBTB5 ZC2HC1C ZFC3H1 ZFP36 ZNF165 ZNF205 ZNF250 ZNF337 ZNF417 ZNF426 ZNF564 ZNF638 ZNF764 ZNF821
Entrez ID		55816	11007
HPRD ID		16317	16101
Ensembl ID		ENSG00000101134	ENSG00000175602
Uniprot IDs		Q9P104	Q15834
PDB IDs		1J0W
Enriched GO Terms of Interacting Partners?		Peptidyl-tyrosine Phosphorylation Positive Regulation Of MAPK Cascade Protein Autophosphorylation Regulation Of MAPK Cascade Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of Signal Transduction Positive Regulation Of Cell Migration Positive Regulation Of Cell Motility Positive Regulation Of Cellular Component Movement Positive Regulation Of Locomotion Regulation Of Protein Kinase B Signaling Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of Phosphorylation Digestive System Development Enzyme Linked Receptor Protein Signaling Pathway Peptidyl-amino Acid Modification Positive Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of Reactive Oxygen Species Biosynthetic Process Cellular Response To Organic Substance Exocrine System Development Regulation Of Cell Migration Response To Growth Factor Regulation Of Nitric Oxide Biosynthetic Process Regulation Of Cell Motility Regulation Of Reactive Oxygen Species Biosynthetic Process Positive Regulation Of DNA Replication Regulation Of Phosphorylation Protein Phosphorylation Regulation Of Locomotion Regulation Of Cellular Component Movement Positive Regulation Of Protein Kinase B Signaling Exocrine Pancreas Development Regulation Of Catalytic Activity Positive Regulation Of Reactive Oxygen Species Metabolic Process Regulation Of Phosphorus Metabolic Process Regulation Of Cell Proliferation Response To Organic Substance Positive Regulation Of Cellular Metabolic Process Regulation Of Cell Death Positive Regulation Of Cell Proliferation Generation Of Neurons Positive Regulation Of Cellular Biosynthetic Process Neurogenesis Regulation Of Signal Transduction Positive Regulation Of Neurogenesis Regulation Of Intracellular Signal Transduction Male Sex Determination Regulation Of DNA Replication Negative Regulation Of Cell Death Phosphorylation	Gene Expression RNA Metabolic Process Cellular Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cell Cycle RNA Biosynthetic Process Transcription, DNA-templated Mitotic Cell Cycle Process Mitotic Cell Cycle DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint Signal Transduction Involved In DNA Damage Checkpoint Regulation Of Cell Cycle Arrest Regulation Of Gene Expression Signal Transduction Involved In Cell Cycle Checkpoint Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Nitrogen Compound Metabolic Process Mitotic G1 DNA Damage Checkpoint Organelle Organization Mitotic G1/S Transition Checkpoint G1 DNA Damage Checkpoint Cellular Metabolic Process Positive Regulation Of Cell Cycle Arrest Cell Cycle Process DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of Transcription, DNA-templated Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Apoptotic Process Macromolecule Biosynthetic Process Negative Regulation Of Mitotic Cell Cycle Phase Transition Signal Transduction In Response To DNA Damage Mitotic DNA Damage Checkpoint Regulation Of RNA Metabolic Process Negative Regulation Of Cellular Metabolic Process Cellular Process Programmed Cell Death DNA Damage Checkpoint Regulation Of Mitotic Cell Cycle Phase Transition RNA Processing Mitotic DNA Integrity Checkpoint Cellular Macromolecule Biosynthetic Process Regulation Of Metabolic Process Regulation Of Cell Cycle Phase Transition Cell Death
Tagcloud ?		adrenal cdh11 combine copy dsc3 epigenomic etv1 exploration gnas h3k27 h3k27me3 h3k4me3 hoxa9 igf2 insm1 instance mark medulla methylations ntrk1 pheochromocytoma ptpre rassf2 ret silenced tgif1 tnfrsf10b trimethylase trimethylated
Tagcloud (Difference) ?		adrenal cdh11 combine copy dsc3 epigenomic etv1 exploration gnas h3k27 h3k27me3 h3k4me3 hoxa9 igf2 insm1 instance mark medulla methylations ntrk1 pheochromocytoma ptpre rassf2 ret silenced tgif1 tnfrsf10b trimethylase trimethylated
Tagcloud (Intersection) ?