EXOC2 and EXOC3

Number of citations of the paper that reports this interaction (PMID 14525976)
66

Data Source:
HPRD (in vivo, two hybrid, in vitro)

		EXOC2	EXOC3
Gene Name		exocyst complex component 2	exocyst complex component 3
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Exocyst Cytosol Plasma Membrane Membrane Intracellular Membrane-bounded Organelle	Exocyst Cytosol Secretory Granule Membrane
	Molecular Function	Protein Binding Ral GTPase Binding Protein Kinase Binding Protein N-terminus Binding	SNARE Binding Protein Binding
	Biological Process	Exocytosis Golgi To Plasma Membrane Transport Organelle Organization Protein Transport Cellular Protein Metabolic Process Membrane Organization	Exocytosis Organelle Organization Protein Transport Cellular Protein Metabolic Process Exocyst Localization Membrane Organization
Pathways		Peptide hormone metabolism Cargo trafficking to the periciliary membrane Organelle biogenesis and maintenance Translocation of GLUT4 to the plasma membrane VxPx cargo-targeting to cilium Assembly of the primary cilium Insulin processing	Peptide hormone metabolism Cargo trafficking to the periciliary membrane Organelle biogenesis and maintenance Translocation of GLUT4 to the plasma membrane VxPx cargo-targeting to cilium Assembly of the primary cilium Insulin processing
Drugs
Diseases
GWAS		Basal cell carcinoma ( 21700618) Black vs. blond hair color ( 18483556) Black vs. red hair color ( 18483556) Dental caries ( 23064961) Non-melanoma skin cancer ( 23548203) Schizophrenia ( 22885689) Tanning ( 19340012)	Ulcerative colitis ( 21297633)
Protein-Protein Interactions		7 interactors: ESX1 EXOC3 EXOC7 EXOC8 RALA SERGEF VPS53	6 interactors: APP BIRC6 BUB3 EXOC2 MLH1 RALA
Entrez ID		55770	11336
HPRD ID		11544	09738
Ensembl ID		ENSG00000112685	ENSG00000180104
Uniprot IDs		B2RBE6 Q96KP1	O60645 Q69YP2
PDB IDs
Enriched GO Terms of Interacting Partners?		Exocyst Localization Exocytosis Secretion By Cell Cellular Protein Complex Localization Protein Complex Localization Vesicle-mediated Transport Secretion Membrane Organization Establishment Of Localization In Cell Cellular Localization Exocyst Assembly Protein Transport Establishment Of Protein Localization Membrane Raft Localization Protein Localization Positive Regulation Of Ran GTPase Activity Transport Labyrinthine Layer Morphogenesis	Cell Cycle Process Exocytosis Cellular Localization Negative Regulation Of Proteolysis Negative Regulation Of Protein Processing Regulation Of Protein Processing Cell Division Cell Cycle MRNA 3'-end Processing Regulation Of Cell Cycle Process Secretion By Cell Organelle Organization Meiotic Spindle Midzone Assembly Meiotic Metaphase I Plate Congression RNA 3'-end Processing Secretion Regulation Of Proteolysis Negative Regulation Of Mitotic Recombination Synaptic Growth At Neuromuscular Junction Microtubule-based Process Negative Regulation Of Catalytic Activity Establishment Of Localization In Cell Collateral Sprouting In Absence Of Injury Negative Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Cellular Metabolic Process Regulation Of Mitotic Recombination Membrane Raft Localization Male Meiosis Chromosome Segregation Negative Regulation Of Protein Metabolic Process Regulation Of Cell Cycle Meiotic Cell Cycle Collateral Sprouting Axon Midline Choice Point Recognition Apoptotic Process Regulation Of Mitotic Cell Cycle Phase Transition Chromosome Segregation Regulation Of Cell Cycle Phase Transition Programmed Cell Death Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Reproduction Cell Death Death Axon Choice Point Recognition Regulation Of Cell Division Negative Regulation Of Endopeptidase Activity Cytoskeleton Organization Negative Regulation Of Peptidase Activity Spindle Midzone Assembly Neuron Remodeling Mitotic Nuclear Division
Tagcloud ?		agouti albinism asip atf1 delta25 dopachrome edn1 edn3 ednrb exocyst kitlg ludwigshafen mc1r microphthalmia oca2 oculocutaneous pigmentation prkacb prkacg prkar1a prkar2a prkar2b proopiomelanocortin slc24a4 slc45a2 tautomerase tpcn2 tubb3 tyrp1	bioactive chemoattractive chemokine chemotactic constitutively cxcl16 dc dendritic dithiocarbamate functionally healing lipopolysaccharide lysoptdoh macrophages mediator modc monocyte organs pertussis pyrrolidine reflected rho secrete separately toxin trafficking transmembrane twofold wound
Tagcloud (Difference) ?		agouti albinism asip atf1 delta25 dopachrome edn1 edn3 ednrb exocyst kitlg ludwigshafen mc1r microphthalmia oca2 oculocutaneous pigmentation prkacb prkacg prkar1a prkar2a prkar2b proopiomelanocortin slc24a4 slc45a2 tautomerase tpcn2 tubb3 tyrp1	bioactive chemoattractive chemokine chemotactic constitutively cxcl16 dc dendritic dithiocarbamate functionally healing lipopolysaccharide lysoptdoh macrophages mediator modc monocyte organs pertussis pyrrolidine reflected rho secrete separately toxin trafficking transmembrane twofold wound
Tagcloud (Intersection) ?