ATF7IP and RPS3A

Number of citations of the paper that reports this interaction (PMID 15231748)
65

Data Source:
HPRD (two hybrid)

		ATF7IP	RPS3A
Gene Name		activating transcription factor 7 interacting protein	ribosomal protein S3A
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Transcription Factor Complex Cytoplasm	Nucleus Nucleolus Cytoplasm Cytosol Focal Adhesion Cytosolic Small Ribosomal Subunit Ribonucleoprotein Complex Extracellular Vesicular Exosome
	Molecular Function	Transcription Corepressor Activity Protein Binding ATPase Activity	RNA Binding Structural Constituent Of Ribosome Protein Binding Poly(A) RNA Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter DNA Methylation Chromatin Organization Transcription, DNA-templated Viral Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Regulation Of RNA Polymerase II Transcriptional Preinitiation Complex Assembly	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Cytoplasmic Translation Translation Translational Initiation Translational Elongation Translational Termination SRP-dependent Cotranslational Protein Targeting To Membrane Gene Expression Viral Process Viral Life Cycle Viral Transcription Cell Differentiation Negative Regulation Of Apoptotic Process Cellular Protein Metabolic Process
Pathways		Chromatin modifying enzymes Chromatin organization PKMTs methylate histone lysines	Nonsense-Mediated Decay (NMD) Translation initiation complex formation Translation SRP-dependent cotranslational protein targeting to membrane Eukaryotic Translation Termination Peptide chain elongation Influenza Infection Viral mRNA Translation L13a-mediated translational silencing of Ceruloplasmin expression Influenza Life Cycle Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Ribosomal scanning and start codon recognition Formation of the ternary complex, and subsequently, the 43S complex Influenza Viral RNA Transcription and Replication GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Initiation Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S Formation of a pool of free 40S subunits Eukaryotic Translation Elongation Cap-dependent Translation Initiation Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS		Prostate-specific antigen levels ( 23359319) Testicular germ cell cancer ( 20543847) Testicular germ cell tumor ( 23666240)	HDL cholesterol ( 20686565)
Protein-Protein Interactions		68 interactors: A2M ACTB ACTG1 AP1B1 CADM1 CEP250 COL4A2 CREB1 CSPG4 DISC1 DMTF1 DNM2 EPG5 FLNB FLT4 GMEB1 GTF2E2 GTF2F1 GTF2H1 HEYL HLA-B HSPG2 KIF13A KRT7 LAMA4 LAMA5 LAMC1 LUC7L2 MACF1 MBD1 MCAM MED4 MRI1 NOMO1 NPR1 PAPPA PAPPA2 PCDH1 PEX6 PIAS3 PKD1 PLEKHB2 POLR2C POLR2D POLR2G PRSS8 PSG3 QRICH1 RPS3A RRBP1 SENP3 SETDB1 SLC12A4 SMAD4 SP1 SPTBN1 SREBF2 STBD1 STRN SUMO3 SUSD1 SVEP1 TRIP12 TTC3 UBE2I ZBTB6 ZNF350 ZNF518A	15 interactors: ATF7IP C11orf49 CCDC50 CHN1 DDIT3 EDEM2 FANCC HGS HSP90AA1 NEDD4 PARP1 SAP18 SOD2 TOE1 VDAC2
Entrez ID		55729	6189
HPRD ID		09811	01606
Ensembl ID		ENSG00000171681	ENSG00000145425
Uniprot IDs		B3KNI7 B3KQF8 F5GX74 G3V1U0 Q6VMQ6	B7Z3M5 P61247
PDB IDs		2RPQ	3J3A
Enriched GO Terms of Interacting Partners?		Transcription Initiation From RNA Polymerase II Promoter Viral Process Positive Regulation Of Viral Transcription Cell Differentiation DNA-templated Transcription, Initiation Transcription Elongation From RNA Polymerase II Promoter 7-methylguanosine MRNA Capping Regulation Of Viral Transcription 7-methylguanosine RNA Capping Positive Regulation Of Viral Process Transcription From RNA Polymerase II Promoter DNA-templated Transcription, Elongation RNA Biosynthetic Process Developmental Process Transcription, DNA-templated Anatomical Structure Development Regulation Of Viral Process Post-Golgi Vesicle-mediated Transport Macromolecule Biosynthetic Process Transcription-coupled Nucleotide-excision Repair Gene Expression RNA Metabolic Process Extracellular Matrix Disassembly Cellular Macromolecule Biosynthetic Process Anatomical Structure Morphogenesis System Development Cell Junction Assembly Cardiovascular System Development Stem Cell Differentiation Anatomical Structure Formation Involved In Morphogenesis Biosynthetic Process Nervous System Development Neurogenesis Angiogenesis Positive Regulation Of Cellular Metabolic Process Nitrogen Compound Metabolic Process Golgi To Plasma Membrane Protein Transport Somatic Stem Cell Maintenance Protein Sumoylation Positive Regulation Of Gene Expression Multicellular Organismal Development Generation Of Neurons Stem Cell Development Blood Vessel Development Establishment Of Protein Localization To Plasma Membrane Positive Regulation Of Cellular Biosynthetic Process Nucleobase-containing Compound Metabolic Process Axon Guidance Golgi Vesicle Transport Vasculature Development	Cellular Response To Superoxide Response To Superoxide Response To Oxygen Radical Cellular Response To Reactive Oxygen Species Protein Targeting To Lysosome Reactive Oxygen Species Metabolic Process Protein Localization To Lysosome Removal Of Superoxide Radicals Response To Unfolded Protein Cellular Response To Stress Positive Regulation Of Metabolic Process Protein Targeting To Vacuole Response To Inorganic Substance Establishment Of Protein Localization To Vacuole Response To Reactive Oxygen Species Cellular Response To Oxidative Stress Negative Regulation Of Signal Transduction Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Nucleic Acid-templated Transcription Regulation Of Signal Transduction Negative Regulation Of RNA Biosynthetic Process Superoxide Metabolic Process Negative Regulation Of Signaling Positive Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of Reactive Oxygen Species Biosynthetic Process Lysosomal Transport Regulation Of Signaling Negative Regulation Of Gene Expression Cytoplasmic Transport Negative Regulation Of Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Regulation Of Nitric Oxide Biosynthetic Process Regulation Of Reactive Oxygen Species Biosynthetic Process Response To Stress Negative Regulation Of Determination Of Dorsal Identity Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Vasodilation By Acetylcholine Involved In Regulation Of Systemic Arterial Blood Pressure Erythrophore Differentiation Age-dependent Response To Reactive Oxygen Species Transmission Of Virus Development Involved In Symbiotic Interaction Cellular Response To DNA Damage Stimulus Establishment Of Protein Localization To Organelle Vacuolar Transport Positive Regulation Of Cellular Biosynthetic Process Response To Organic Substance Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Reactive Oxygen Species Metabolic Process Neuron Development
Tagcloud ?		acgh adherent cce cd15 cd29 cd44 cd90 continuously csmd1 cultivation cytokeratins cytometric devastating doubling explant grin2b hypercalcemia hypercalcemic karyotype lentiviral oligo outgrowth paralleled park2 proliferating sccoht similarities subpopulations vimentin
Tagcloud (Difference) ?		acgh adherent cce cd15 cd29 cd44 cd90 continuously csmd1 cultivation cytokeratins cytometric devastating doubling explant grin2b hypercalcemia hypercalcemic karyotype lentiviral oligo outgrowth paralleled park2 proliferating sccoht similarities subpopulations vimentin
Tagcloud (Intersection) ?