LIMS2 and MTUS2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		LIMS2	MTUS2
Gene Name		LIM and senescent cell antigen-like domains 2	microtubule associated tumor suppressor candidate 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytosol Plasma Membrane Focal Adhesion	Centrosome Cytoplasmic Microtubule
	Molecular Function	Zinc Ion Binding	Protein Binding Microtubule Binding Protein Homodimerization Activity
	Biological Process	Single Organismal Cell-cell Adhesion Cell Junction Assembly Negative Regulation Of Apoptotic Process Cell-cell Junction Organization Negative Regulation Of Neural Precursor Cell Proliferation Negative Regulation Of Hepatocyte Proliferation Positive Regulation Of Integrin-mediated Signaling Pathway
Pathways		Cell junction organization Cell-extracellular matrix interactions
Drugs
Diseases
GWAS		Alzheimer's disease (cognitive decline) ( 23535033)	Insomnia (caffeine-induced) ( 22754043) Obesity-related traits ( 23251661)
Protein-Protein Interactions		13 interactors: APP CALCOCO2 GOLGA2 HIPK3 ILK KRT40 KRTAP10-3 KRTAP10-5 KRTAP10-7 MDFI MTUS2 NOTCH2NL RCHY1	167 interactors: AEN AES AFF4 ALS2CR11 AQP1 ARNT2 BMP7 BYSL C14orf105 C19orf66 C1orf109 C1orf216 C20orf195 C21orf58 C8orf34 CATIP CATSPER1 CBX8 CCDC116 CCDC146 CCDC17 CCDC60 CCHCR1 CDC20B CDC73 CDK18 CDK5R1 CDKL3 CEP57L1 CEP95 CERK COG2 CREB5 CRY2 CTSZ CWF19L2 CXCL11 CXCL16 DCDC2B DCTN4 DLGAP5 DMRT3 DOCK2 DTNB FAM13C FAM161A FAM71E2 FAM74A4 FAM90A1 FBXL18 FBXO34 FCHSD2 GAL3ST2 GOLGA2P11 GTF2I GTPBP10 HAUS1 HCK HDAC4 HSF2 IQCE ITGB5 ITSN1 KAT5 KIF1A LENG1 LIMS2 LINC00636 LMO2 LNX1 LOC153684 LRR1 LYSMD1 MAGEA8 MARK4 MFAP1 MTMR6 NDEL1 NDOR1 NELFE NUBPL NUDT10 ODF1 PDE4DIP PIN1 PKP2 PLK4 PLSCR4 POLDIP2 POLDIP3 PPHLN1 PPP1R18 PRKAA1 PRPF31 PSMA1 PTPMT1 RAB3IL1 RGS2 RHPN1 RIBC2 ROBO3 RPA1 RPL9 RTP5 SCEL SDCBP SELM SETD5 SH2D4A SH3RF2 SLC23A1 SLC25A6 SLIRP SMARCE1 SNAI1 SNHG11 SNRPA SNRPB2 SNW1 SPATA8 SPG7 STK16 SYT6 TAF13 THAP7 TP53RK TRIM42 TSGA10IP TSHZ3 TXN2 USP2 WAC WDYHV1 ZBTB38 ZC2HC1C ZFC3H1 ZFP2 ZFP64 ZFYVE21 ZMAT2 ZNF136 ZNF20 ZNF224 ZNF232 ZNF250 ZNF3 ZNF329 ZNF337 ZNF410 ZNF415 ZNF417 ZNF426 ZNF439 ZNF440 ZNF490 ZNF572 ZNF581 ZNF587 ZNF599 ZNF607 ZNF624 ZNF655 ZNF670 ZNF785 ZNF844 ZSCAN12 ZSCAN26
Entrez ID		55679	23281
HPRD ID		06389	11108
Ensembl ID		ENSG00000072163
Uniprot IDs		B3KNZ3 Q7Z4I7	J3KQA9 Q5JR59
PDB IDs		3IXE
Enriched GO Terms of Interacting Partners?		Regulation Of Protein Kinase Activity Regulation Of Binding Regulation Of Kinase Activity Regulation Of MAP Kinase Activity Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Phosphorylation Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Metabolic Process Regulation Of JUN Kinase Activity Positive Regulation Of Protein Metabolic Process Negative Regulation Of Binding Regulation Of Phosphorylation Synaptic Growth At Neuromuscular Junction Peptidyl-serine Phosphorylation Regulation Of Phosphorus Metabolic Process Regulation Of MAPK Cascade Notch Signaling Pathway Collateral Sprouting In Absence Of Injury Regulation Of Protein Binding Regulation Of JNK Cascade Collateral Sprouting Axon Midline Choice Point Recognition Regulation Of Stress-activated MAPK Cascade Negative Regulation Of Catalytic Activity Platelet Activation Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Negative Regulation Of Cellular Protein Metabolic Process Phosphorylation Positive Regulation Of MAP Kinase Activity Negative Regulation Of Protein Kinase Activity Axon Choice Point Recognition Negative Regulation Of Protein Metabolic Process Negative Regulation Of Kinase Activity Positive Regulation Of Protein Modification Process Neuron Remodeling Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Cardiac Muscle Cell Apoptotic Process Positive Regulation Of Protein Serine/threonine Kinase Activity Negative Regulation Of JUN Kinase Activity Regulation Of Developmental Growth Positive Regulation Of Proteolysis Negative Regulation Of Transferase Activity Regulation Of Wnt Signaling Pathway Fibroblast Migration Extracellular Fibril Organization Negative Regulation Of Protein Phosphorylation Regulation Of Catalytic Activity MRNA Transcription Negative Regulation Of Striated Muscle Cell Apoptotic Process Negative Regulation Of Smooth Muscle Cell Migration	RNA Biosynthetic Process Transcription, DNA-templated RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Cellular Metabolic Process Cellular Process Regulation Of Cellular Process Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Metabolic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Gene Expression Mitochondrion Morphogenesis Histone Ubiquitination T Cell Chemotaxis Histone H2B Ubiquitination Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Tight Junction Assembly Cellular Response To Lipid Axon Cargo Transport Viral Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Developmental Process Positive Regulation Of Gene Expression Transepithelial Transport Signal Transduction By P53 Class Mediator Positive Regulation Of Cellular Metabolic Process Regulation Of Cell Cycle Lymphocyte Chemotaxis Regulation Of Cell Cycle Process Negative Regulation Of Phosphatase Activity T Cell Migration
Tagcloud ?		al7a1 arhgap1 c25h16orf71 conceptus ddx58 degs endometria ensbtat00000050193 estrus f2rl2 fbxl7 herc6 ifi16 ifnt insemination loc507810 mgc127874 mgc128929 parp12 rnaseq rnf213 samd9 serbp1 srgap2 tbc1d1 wbscr17 znfx1 zswim4 zxfx1
Tagcloud (Difference) ?		al7a1 arhgap1 c25h16orf71 conceptus ddx58 degs endometria ensbtat00000050193 estrus f2rl2 fbxl7 herc6 ifi16 ifnt insemination loc507810 mgc127874 mgc128929 parp12 rnaseq rnf213 samd9 serbp1 srgap2 tbc1d1 wbscr17 znfx1 zswim4 zxfx1
Tagcloud (Intersection) ?