SYBU and KIF5B

Number of citations of the paper that reports this interaction (PMID 16157705)
32

Data Source:
HPRD (in vitro)

		SYBU	KIF5B
Gene Name		syntabulin (syntaxin-interacting)	kinesin family member 5B
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Nucleoplasm Mitochondrion Microtubule Integral Component Of Membrane Cytoplasmic Membrane-bounded Vesicle Vesicle Intracellular Membrane-bounded Organelle Dense Body	Cytoplasm Microtubule Organizing Center Kinesin Complex Microtubule Membrane Endocytic Vesicle Vesicle Ciliary Rootlet Neuron Projection Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Microtubule Binding Syntaxin-1 Binding Kinesin Binding	Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding ATP-dependent Microtubule Motor Activity, Plus-end-directed ATPase Activity
	Biological Process	Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus	Microtubule-based Movement Cytoplasm Organization Axon Guidance Cytoskeleton-dependent Intracellular Transport Positive Regulation Of Synaptic Transmission, GABAergic Stress Granule Disassembly Regulation Of Membrane Potential Positive Regulation Of Potassium Ion Transport Cellular Protein Metabolic Process Vesicle Transport Along Microtubule Plus-end-directed Vesicle Transport Along Microtubule Positive Regulation Of Establishment Of Protein Localization To Plasma Membrane
Pathways			Peptide hormone metabolism MHC class II antigen presentation Kinesins Insulin processing Factors involved in megakaryocyte development and platelet production Adaptive Immune System
Drugs
Diseases
GWAS			Bipolar disorder (mood-incongruent) ( 23092984)
Protein-Protein Interactions		6 interactors: ATXN1 DISC1 DTNBP1 EXOC1 KIF5B RPL29	23 interactors: APC CDC5L DTNB GSK3B KIF5A KLC3 KTN1 NCOA2 NDRG1 PRKAR2B RAPGEF2 RRBP1 SNAP23 SNAP25 SYBU TAX1BP1 VPS52 YWHAB YWHAG YWHAH YWHAQ YWHAZ ZBTB8A
Entrez ID		55638	3799
HPRD ID		07902	07214
Ensembl ID		ENSG00000147642	ENSG00000170759
Uniprot IDs		B7Z4D2 Q9NX95	P33176 Q6P164
PDB IDs			1BG2 1MKJ 2P4N 4HNA
Enriched GO Terms of Interacting Partners?		Cellular Localization Establishment Of Localization In Cell Intracellular Transport Positive Regulation Of Synaptic Transmission Microtubule-based Transport Stress Granule Disassembly Cytoskeleton-dependent Intracellular Transport Microtubule-based Process Membrane Organization Establishment Of Vesicle Localization Vesicle Localization Plus-end-directed Vesicle Transport Along Microtubule Multicellular Organismal Development Regulation Of Dopamine Receptor Signaling Pathway Cytoplasm Organization Regulation Of Membrane Potential Transport Negative Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Platelet Dense Granule Organization Regulation Of Synaptic Transmission Microtubule-based Movement Establishment Of Organelle Localization Developmental Process Regulation Of Signaling Positive Regulation Of Neurotransmitter Secretion Organelle Organization Positive Regulation Of Synaptic Transmission, GABAergic Movement Of Cell Or Subcellular Component Mitochondrial Calcium Ion Homeostasis Organelle Localization Generation Of Neurons Regulation Of Synapse Maturation Anterograde Synaptic Vesicle Transport Melanosome Organization Regulation Of Dopamine Secretion TOR Signaling Pigment Granule Organization Neurogenesis Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Positive Regulation Of Establishment Of Protein Localization To Plasma Membrane Positive Regulation Of Protein Localization To Plasma Membrane Positive Regulation Of Neuroblast Proliferation Anterograde Axon Cargo Transport Positive Regulation Of Potassium Ion Transport Synaptic Transmission Protein Localization Vesicle Transport Along Microtubule Regulation Of Synaptic Transmission, GABAergic Regulation Of Ion Transport Organelle Disassembly	Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrion Organization Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Regulation Of Mitochondrion Organization Regulation Of Protein Localization Regulation Of Establishment Of Protein Localization Regulation Of Cellular Localization Protein Localization Positive Regulation Of Apoptotic Signaling Pathway Membrane Organization Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Negative Regulation Of Dendrite Morphogenesis Positive Regulation Of Organelle Organization Positive Regulation Of Intracellular Transport Protein Transport Establishment Of Protein Localization Regulation Of Synaptic Plasticity Negative Regulation Of Dendrite Development Apoptotic Signaling Pathway Intrinsic Apoptotic Signaling Pathway Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Apoptotic Process Apoptotic Process Mast Cell Activation Programmed Cell Death Regulation Of Intracellular Transport Intracellular Signal Transduction Cell Death Cellular Localization Death Regulation Of Apoptotic Process Intracellular Transport Regulation Of Signaling Establishment Of Localization In Cell Regulation Of Cell Death Negative Regulation Of Protein Serine/threonine Kinase Activity Regulation Of Synaptic Transmission Neurogenesis Positive Regulation Of Signal Transduction Histamine Secretion By Mast Cell Signaling Regulation Of Organelle Organization Nervous System Development Cell Communication Transport Regulation Of Cellular Component Organization Synaptic Vesicle Priming Histamine Secretion
Tagcloud ?			actionable adenocarcinomas akt1 alk braf capture ccdc6 cd74 clip4 deemed driver fusions g719a genomic introns map2k1 nccn ngs nras pack pik3ca profiling rearranged ret ros1 socs5 targetable uniform v600e
Tagcloud (Difference) ?			actionable adenocarcinomas akt1 alk braf capture ccdc6 cd74 clip4 deemed driver fusions g719a genomic introns map2k1 nccn ngs nras pack pik3ca profiling rearranged ret ros1 socs5 targetable uniform v600e
Tagcloud (Intersection) ?