PPP1R9A and ACTG1

Number of citations of the paper that reports this interaction (PMID 9362513)
36

Data Source:
HPRD (in vivo, in vitro)

		PPP1R9A	ACTG1
Gene Name		protein phosphatase 1, regulatory subunit 9A	actin gamma 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cell Junction Filopodium Growth Cone Cortical Actin Cytoskeleton Dendritic Spine Synapse	Extracellular Space Nucleus Cytosol Cytoskeleton Plasma Membrane Membrane Myofibril Filamentous Actin Extracellular Vesicular Exosome Blood Microparticle
	Molecular Function	Protein Binding Actin Filament Binding	Structural Constituent Of Cytoskeleton Protein Binding ATP Binding Ubiquitin Protein Ligase Binding Identical Protein Binding
	Biological Process	Actin Filament Organization Calcium-mediated Signaling Neuron Projection Development	Retina Homeostasis Movement Of Cell Or Subcellular Component Axon Guidance Cell Junction Assembly Adherens Junction Organization Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Innate Immune Response Sarcomere Organization Cell-cell Junction Organization Vascular Endothelial Growth Factor Receptor Signaling Pathway Ephrin Receptor Signaling Pathway Membrane Organization Platelet Aggregation
Pathways			Axon guidance Gap junction degradation Adherens junctions interactions Translocation of GLUT4 to the plasma membrane L1CAM interactions Recycling pathway of L1 VEGFA-VEGFR2 Pathway EPHB-mediated forward signaling Interaction between L1 and Ankyrins Cell-cell junction organization EPH-ephrin mediated repulsion of cells Gap junction trafficking and regulation EPH-Ephrin signaling Fcgamma receptor (FCGR) dependent phagocytosis Regulation of actin dynamics for phagocytic cup formation Innate Immune System Cell junction organization Formation of annular gap junctions Gap junction trafficking Signaling by VEGF Cell-extracellular matrix interactions
Drugs
Diseases
GWAS
Protein-Protein Interactions		7 interactors: ACTG1 PPP1CA PPP1R2 PPP1R9B PRKAR1B RPS6KB1 TGOLN2	60 interactors: ABLIM1 ACTB ANXA5 APOE ATF7IP BCAP31 BRCA1 CAP1 CAP2 CAPZA3 CCDC22 CDKN2A CFL1 CFL2 COTL1 CTBP2 CTTN CYBB DISC1 DNASE1 DSTN DYNLL1 EHHADH EIF6 FHOD1 FPR1 GIT2 GSN GZMA GZMK LGALS13 LIG4 LSP1 MAP1A MAPK6 MYO1A MYOC NDRG1 NR3C2 PFN2 PLD1 PLEC PPP1R9A PRSS23 PSEN2 PTPRO RPS6KA5 SCIN SH3GL2 ST3GAL3 SUMO4 TMSB4X TMSB4Y TNIK VASP VIL1 WASF1 WASL WDYHV1 WIPF1
Entrez ID		55607	71
HPRD ID		16000	00017
Ensembl ID		ENSG00000158528	ENSG00000184009
Uniprot IDs		B7ZLX4 F8W7J9 Q9ULJ8	P63261
PDB IDs		1WF8
Enriched GO Terms of Interacting Partners?		Energy Reserve Metabolic Process Enzyme Linked Receptor Protein Signaling Pathway Energy Derivation By Oxidation Of Organic Compounds Response To Glucagon Glycogen Metabolic Process Generation Of Precursor Metabolites And Energy Cellular Response To Organonitrogen Compound Polysaccharide Metabolic Process Regulation Of Signaling Cellular Response To Growth Factor Stimulus Response To Growth Factor Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Response To External Stimulus Response To Wounding Regulation Of Opioid Receptor Signaling Pathway Positive Regulation Of Skeletal Muscle Tissue Growth Cellular Response To Organic Substance Negative Regulation Of Catalytic Activity Cellular Response To Morphine Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Response To Organonitrogen Compound Cellular Response To Isoquinoline Alkaloid Regulation Of Cell Growth By Extracellular Stimulus Regulation Of Extrinsic Apoptotic Signaling Pathway Skeletal Muscle Atrophy Cellular Carbohydrate Metabolic Process Striated Muscle Atrophy Response To Leucine Response To Organic Substance Muscle Atrophy Learning Or Memory Negative Regulation Of CAMP-dependent Protein Kinase Activity Skeletal Muscle Adaptation Cognition Regulation Of Glycogen Catabolic Process Regulation Of Signal Transduction Cellular Response To Peptide Hormone Stimulus Signal Transduction Locomotion Cellular Response To Peptide Regulation Of Exit From Mitosis Regulation Of CAMP-dependent Protein Kinase Activity Cell Cycle Positive Regulation Of Translational Initiation Cell Surface Receptor Signaling Pathway Signaling Activation Of Protein Kinase A Activity Cell Communication Regulation Of Phosphorus Metabolic Process Movement Of Cell Or Subcellular Component	Cytoskeleton Organization Regulation Of Actin Cytoskeleton Organization Regulation Of Cellular Component Organization Positive Regulation Of Organelle Organization Regulation Of Actin Filament-based Process Actin Cytoskeleton Organization Positive Regulation Of Cytoskeleton Organization Actin Polymerization Or Depolymerization Regulation Of Cytoskeleton Organization Actin Filament-based Process Actin Filament Organization Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Regulation Of Organelle Organization Organelle Organization Regulation Of Cellular Component Size Chemotaxis Cell Projection Organization Neurogenesis Negative Regulation Of Cytoskeleton Organization Regulation Of Actin Filament Depolymerization Regulation Of Protein Complex Assembly Regulation Of Actin Filament Polymerization Negative Regulation Of Actin Filament Polymerization Negative Regulation Of Protein Complex Assembly Neuron Projection Development Negative Regulation Of Protein Polymerization Movement Of Cell Or Subcellular Component Axon Guidance Generation Of Neurons Actin Filament Severing Positive Regulation Of Cellular Component Biogenesis Locomotion Regulation Of Protein Depolymerization Cell Development Response To External Stimulus Neuron Development Nervous System Development Axon Development Regulation Of Protein Complex Disassembly Regulation Of Cell Projection Organization Actin Filament Depolymerization Neuron Projection Morphogenesis Axonogenesis Neuron Differentiation Cell Projection Morphogenesis Cell Part Morphogenesis Cell Morphogenesis Involved In Neuron Differentiation Positive Regulation Of Actin Filament Polymerization Signal Transduction
Tagcloud ?		biallelically cancerous cdkn1c coordinately deregulated deregulating deregulation dmr dmrs exclusive h19 hoxc6 hyper hypo igf2 ign imprinted imprinting lit1 meg3 ndn plagl1 presumptive prostatic pyrosequencing qrt silico wondered zac1	alteration birc7 chrcc chromophobe cpq distinctions ectopic enabled exome faah2 fusions met mitf mutated nccrccs nf2 oncocytoma oncocytomas papillary pdhb pdxdc1 pnkd prcc rcc slc5a3 transcriptome trcc unreported znf765
Tagcloud (Difference) ?		biallelically cancerous cdkn1c coordinately deregulated deregulating deregulation dmr dmrs exclusive h19 hoxc6 hyper hypo igf2 ign imprinted imprinting lit1 meg3 ndn plagl1 presumptive prostatic pyrosequencing qrt silico wondered zac1	alteration birc7 chrcc chromophobe cpq distinctions ectopic enabled exome faah2 fusions met mitf mutated nccrccs nf2 oncocytoma oncocytomas papillary pdhb pdxdc1 pnkd prcc rcc slc5a3 transcriptome trcc unreported znf765
Tagcloud (Intersection) ?