PPP5C and CPNE4

Number of citations of the paper that reports this interaction (PMID 12522145)
20

Data Source:
HPRD (in vitro)

		PPP5C	CPNE4
Gene Name		protein phosphatase 5, catalytic subunit	copine IV
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Membrane Neuron Projection Neuronal Cell Body Intracellular Membrane-bounded Organelle	Extracellular Vesicular Exosome
	Molecular Function	RNA Binding Phosphoprotein Phosphatase Activity Protein Serine/threonine Phosphatase Activity Signal Transducer Activity Protein Binding Lipid Binding Identical Protein Binding Metal Ion Binding
	Biological Process	DNA Repair Transcription, DNA-templated Protein Dephosphorylation Mitotic Nuclear Division Signal Transduction Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Response To Morphine Protein Heterooligomerization
Pathways
Drugs
Diseases
GWAS			Amyotrophic lateral sclerosis ( 22959728) Neutrophil count ( 21507922)
Protein-Protein Interactions		22 interactors: APP CDC16 CDC27 CDK20 CHORDC1 CPNE1 CPNE2 CPNE4 CRY2 CSE1L DISC1 EGFR ESR2 GNA12 GNA13 HSP90AA1 HTR2A MAP3K5 MAP3K7 MAPT PPP2R1A PPP2R3A	16 interactors: ACTB BCOR BICD1 CCDC22 CEP162 CPNE1 MAP2K1 MYCBP PDCD6 PITPNM2 PPP5C RDX SKIL SPTBN1 UBE2M UBE2O
Entrez ID		5536	131034
HPRD ID		02805	05017
Ensembl ID		ENSG00000011485	ENSG00000196353
Uniprot IDs		B7Z1I1 P53041	Q96A23
PDB IDs		1A17 1S95 1WAO 2BUG 3H60 3H61 3H62 3H63 3H64 3H66 3H67 3H68 3H69
Enriched GO Terms of Interacting Partners?		Regulation Of Catalytic Activity Regulation Of Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Metabolic Process Regulation Of Protein Catabolic Process Regulation Of Cellular Component Organization Cell Death Death Regulation Of Metabolic Process Regulation Of Protein Kinase Activity Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Kinase Activity Regulation Of Signal Transduction Regulation Of MAP Kinase Activity Positive Regulation Of Proteolysis Positive Regulation Of Transferase Activity Positive Regulation Of Protein Modification Process Apoptotic Process Regulation Of Signaling Programmed Cell Death Regulation Of Proteolysis Regulation Of Phosphorus Metabolic Process Regulation Of Protein Phosphorylation Positive Regulation Of Catalytic Activity Intracellular Receptor Signaling Pathway Activation Of MAPKK Activity Positive Regulation Of Metabolic Process Regulation Of Peptidyl-tyrosine Phosphorylation Positive Regulation Of MAP Kinase Activity Positive Regulation Of Protein Catabolic Process Negative Regulation Of Signaling Negative Regulation Of Catalytic Activity Metal Ion Homeostasis Positive Regulation Of Phospholipase Activity Cellular Protein Metabolic Process Signal Transduction Positive Regulation Of Signal Transduction Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Regulation Of Phospholipase Activity Chemical Homeostasis Positive Regulation Of Lipase Activity Regulation Of Phosphorylation Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Negative Regulation Of Protein Metabolic Process Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Anatomical Structure Morphogenesis Intracellular Signal Transduction Positive Regulation Of Protein Serine/threonine Kinase Activity Cell Surface Receptor Signaling Pathway	Cellular Component Assembly Enzyme Linked Receptor Protein Signaling Pathway Vascular Endothelial Growth Factor Receptor Signaling Pathway Anatomical Structure Morphogenesis Protein Heterooligomerization Golgi To Plasma Membrane Transport Intracellular Transport Protein Monoubiquitination Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Actin Filament Capping Organelle Transport Along Microtubule Cell Projection Organization Regulation Of Proteinase Activated Receptor Activity Negative Regulation Of Histone H3-K36 Methylation Negative Regulation Of Phospholipase C-activating G-protein Coupled Receptor Signaling Pathway Negative Regulation Of Actin Filament Depolymerization Positive Regulation Of Signal Transduction Regulation Of Cellular Component Organization Regulation Of Actin Filament Depolymerization Negative Regulation Of Actin Filament Polymerization Regulation Of Signal Transduction Establishment Of Localization In Cell Negative Regulation Of Tooth Mineralization Negative Regulation Of Phospholipase C Activity Negative Regulation Of Protein Polymerization Post-Golgi Vesicle-mediated Transport Positive Regulation Of Intracellular Signal Transduction Anatomical Structure Development Negative Regulation Of Protein Complex Disassembly Transport Cell Projection Morphogenesis Vesicle-mediated Transport Minus-end-directed Organelle Transport Along Microtubule Axon Guidance Cell Part Morphogenesis Regulation Of Signaling Negative Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Protein Depolymerization Regulation Of Organelle Organization Regulation Of Golgi Inheritance Protein Oligomerization Regulation Of Protein Complex Disassembly Specification Of Axis Polarity Vascular Endothelial Growth Factor Receptor-2 Signaling Pathway Cellular Localization Negative Regulation Of Protein Complex Assembly Microtubule-based Transport Regulation Of Vascular Smooth Muscle Contraction Common-partner SMAD Protein Phosphorylation Negative Regulation Of Odontogenesis
Tagcloud ?		cantharidin catalytic communities date desired fluorescent greatly libraries microcystin okadaic optimization pharmaceutical phosphatase phosphatases pp1 pp1alpha pp1calpha ppp1c representative robust screen selectively share simultaneously threonine z
Tagcloud (Difference) ?		cantharidin catalytic communities date desired fluorescent greatly libraries microcystin okadaic optimization pharmaceutical phosphatase phosphatases pp1 pp1alpha pp1calpha ppp1c representative robust screen selectively share simultaneously threonine z
Tagcloud (Intersection) ?