LIN7C and BAIAP2

Number of citations of the paper that reports this interaction (PMID 14596909)
7

Data Source:
HPRD (two hybrid, in vitro, in vivo)

		LIN7C	BAIAP2
Gene Name		lin-7 homolog C (C. elegans)	BAI1-associated protein 2
Image
Gene Ontology Annotations	Cellular Component	Cytoplasm Plasma Membrane Cell-cell Junction Tight Junction Postsynaptic Density Basolateral Plasma Membrane Neuron Projection Synapse Postsynaptic Membrane Extracellular Vesicular Exosome MPP7-DLG1-LIN7 Complex	Ruffle Nucleoplasm Cytoplasm Cytosol Plasma Membrane Actin Cytoskeleton Filopodium Neuron Projection Extracellular Vesicular Exosome
	Molecular Function	Cytoskeletal Protein Binding Protein Domain Specific Binding PDZ Domain Binding L27 Domain Binding	Protein Binding Protein C-terminus Binding Cytoskeletal Adaptor Activity Identical Protein Binding Proline-rich Region Binding
	Biological Process	Morphogenesis Of An Epithelial Sheet Exocytosis Neurotransmitter Secretion Asymmetric Protein Localization Protein Transport Maintenance Of Epithelial Cell Apical/basal Polarity Protein Localization To Basolateral Plasma Membrane	Plasma Membrane Organization Axonogenesis Insulin Receptor Signaling Pathway Regulation Of Cell Shape Response To Bacterium Dendrite Development Regulation Of Actin Cytoskeleton Organization Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Innate Immune Response Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of Synaptic Plasticity Actin Filament Bundle Assembly Actin Crosslink Formation
Pathways			Signaling by VEGF Fcgamma receptor (FCGR) dependent phagocytosis VEGFA-VEGFR2 Pathway Regulation of actin dynamics for phagocytic cup formation Innate Immune System
Drugs
Diseases
GWAS		Bone mineral density ( 22504420)
Protein-Protein Interactions		4 interactors: ABCA1 BAIAP2 HTR2C KCNJ12	32 interactors: APP ATN1 BAI1 C14orf1 C19orf25 CDC42 DIAPH1 ENAH EPS8 ESPN KANK1 KDM1A LIN7A LIN7B LIN7C MARK2 NCKIPSD NEDD4 PAK1 PBX2 PRR13 RAC1 RTN4 SF3B4 SHANK1 SHANK2 SRPK2 TP53BP2 WASF1 WASF2 WASL YWHAG
Entrez ID		55327	10458
HPRD ID		17279	05686
Ensembl ID		ENSG00000148943	ENSG00000175866
Uniprot IDs		Q9NUP9	B4DWA1 I3L4C2 Q9UQB8
PDB IDs		3LRA	1WDZ 1Y2O 2YKT 3RNJ
Enriched GO Terms of Interacting Partners?		Phospholipase C-activating Serotonin Receptor Signaling Pathway Regulation Of Corticotropin-releasing Hormone Secretion Positive Regulation Of Phosphatidylinositol Biosynthetic Process Interleukin-1 Beta Secretion Phagocytosis Apolipoprotein A-I-mediated Signaling Pathway Positive Regulation Of Phospholipid Biosynthetic Process Interleukin-1 Secretion Negative Regulation Of Cholesterol Storage High-density Lipoprotein Particle Assembly Intracellular Cholesterol Transport Intracellular Sterol Transport Phospholipid Homeostasis Ion Transport Platelet Dense Granule Organization Response To External Stimulus Endomembrane System Organization Cellular Component Assembly Response To Nutrient Levels Phospholipid Efflux Phagocytosis, Engulfment Transport Response To Low-density Lipoprotein Particle Interleukin-1 Beta Production Response To Extracellular Stimulus Response To Bacterium Serotonin Receptor Signaling Pathway Cellular Response To Cholesterol Negative Regulation Of Macrophage Derived Foam Cell Differentiation Response To Drug Reverse Cholesterol Transport Response To Laminar Fluid Shear Stress Membrane Invagination Positive Regulation Of Cytosolic Calcium Ion Concentration Involved In Phospholipase C-activating G-protein Coupled Signaling Pathway Actin Crosslink Formation Protein-lipid Complex Assembly Response To Lipoprotein Particle Cellular Response To Sterol Positive Regulation Of Cholesterol Efflux Negative Regulation Of Lipid Storage Signaling Ion Homeostasis Positive Regulation Of Cholesterol Transport CGMP Biosynthetic Process Cell Communication Synaptic Transmission Regulation Of Appetite Regulation Of Cholesterol Efflux Response To Cholesterol Potassium Ion Import	Regulation Of Cytoskeleton Organization Nervous System Development Regulation Of Organelle Organization Establishment Or Maintenance Of Apical/basal Cell Polarity Anatomical Structure Development Regulation Of Cellular Component Organization Regulation Of Cell Projection Organization System Development Multicellular Organismal Development Maintenance Of Cell Polarity Generation Of Neurons Actin Cytoskeleton Organization Developmental Process Neuron Projection Development Actin Filament Organization Actin Filament-based Process Neurogenesis Cytoskeleton Organization Cell Projection Organization Regulation Of Cell Projection Assembly Regulation Of Actin Cytoskeleton Organization Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Neuron Development Protein Localization To Basolateral Plasma Membrane Locomotion Regulation Of Actin Filament-based Process Maintenance Of Epithelial Cell Apical/basal Polarity Organelle Organization Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Cellular Protein Localization Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Positive Regulation Of Cell Projection Organization Maintenance Of Apical/basal Cell Polarity Immune Response-activating Cell Surface Receptor Signaling Pathway Cellular Localization Actin Polymerization Or Depolymerization Neuron Differentiation Regulation Of Cell Morphogenesis Establishment Or Maintenance Of Cell Polarity Cell Differentiation Cell Development Movement Of Cell Or Subcellular Component Cell Morphogenesis Involved In Differentiation Signaling Cellular Component Assembly Cell Communication Immune Response-regulating Cell Surface Receptor Signaling Pathway Axon Development Cell Morphogenesis
Tagcloud ?		adiposity alleles bcdin3d bdnf bmi chinese circumference dgkg etv5 europeans faim2 former fto gnpda2 hong kctd15 kong loci lost mc4r modestly mtch2 negr1 obesity sec16b sh2b1 t2d tmem18 waist
Tagcloud (Difference) ?		adiposity alleles bcdin3d bdnf bmi chinese circumference dgkg etv5 europeans faim2 former fto gnpda2 hong kctd15 kong loci lost mc4r modestly mtch2 negr1 obesity sec16b sh2b1 t2d tmem18 waist
Tagcloud (Intersection) ?