PPP3CB and MYOZ3

Number of citations of the paper that reports this interaction (PMID 11842093)
29

Data Source:
HPRD (in vivo)

		PPP3CB	MYOZ3
Gene Name		protein phosphatase 3, catalytic subunit, beta isozyme	myozenin 3
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytosol Plasma Membrane Calcineurin Complex Z Disc T-tubule	Z Disc
	Molecular Function	Protein Serine/threonine Phosphatase Activity Calcium Ion Binding Protein Binding Calmodulin Binding Drug Binding Enzyme Binding Protein Phosphatase 2B Binding Calmodulin-dependent Protein Phosphatase Activity Protein Dimerization Activity	Protein Binding
	Biological Process	Negative Regulation Of T Cell Mediated Cytotoxicity Protein Phosphorylation Protein Dephosphorylation Signal Transduction Heart Development Learning Memory Dephosphorylation Calcium Ion-dependent Exocytosis T Cell Differentiation Locomotion Involved In Locomotory Behavior Calcineurin-NFAT Signaling Cascade Response To Cytokine Social Behavior Cellular Response To Drug Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Fc-epsilon Receptor Signaling Pathway T Cell Proliferation T Cell Activation T Cell Homeostasis Innate Immune Response Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Synaptic Plasticity Axon Extension Regulation Of Insulin Secretion Positive Regulation Of NFAT Protein Import Into Nucleus
Pathways		Signaling by GPCR Ca2+ pathway Opioid Signalling DARPP-32 events Fc epsilon receptor (FCERI) signaling FCERI mediated Ca+2 mobilization Signaling by Wnt Innate Immune System beta-catenin independent WNT signaling
Drugs
Diseases
GWAS
Protein-Protein Interactions		12 interactors: CABIN1 IRAK1 IRF2 JUN MARCH7 MYOZ2 MYOZ3 NFATC2 SLC8A1 SLC8A2 SLC8A3 SOCS3	8 interactors: ACTN1 ACTN2 FLNC LDB3 MAPK6 PPP3CA PPP3CB TCAP
Entrez ID		5532	91977
HPRD ID		00235	17624
Ensembl ID		ENSG00000107758	ENSG00000164591
Uniprot IDs		P16298	Q8TDC0
PDB IDs
Enriched GO Terms of Interacting Partners?		Calcium Ion Export Response To Wounding Innate Immune Response Response To Organonitrogen Compound Response To Stress Blood Coagulation Hemostasis Response To Purine-containing Compound Cellular Response To Organic Substance Cell Communication Sodium Ion Transmembrane Transport Regulation Of Body Fluid Levels Calcium Ion Import Calcium Ion Transmembrane Transport Wound Healing Immune Response Regulation Of Innate Immune Response Immune System Process Sodium Ion Transport Defense Response Calcium Ion Transport Into Cytosol Cytosolic Calcium Ion Transport Response To Cytokine Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Toll-like Receptor TLR6:TLR2 Signaling Pathway Positive Regulation Of Smooth Muscle Cell Proliferation Toll-like Receptor TLR1:TLR2 Signaling Pathway Calcium Ion Transport Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway Response To Organic Substance MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Regulation Of Immune Response Cellular Response To Potassium Ion Starvation MyD88-dependent Toll-like Receptor Signaling Pathway Toll-like Receptor 4 Signaling Pathway Regulation Of Cytokine-mediated Signaling Pathway Calcium Ion Import Into Cell Calcium Ion Export From Cell Leading Edge Cell Differentiation Sodium Ion Import Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress Cytokine-mediated Signaling Pathway Regulation Of Smooth Muscle Cell Proliferation Immune Response-regulating Signaling Pathway Type I Interferon Signaling Pathway Cellular Response To Type I Interferon	Striated Muscle Cell Development Muscle Cell Development Muscle Fiber Development Striated Muscle Cell Differentiation Calcineurin-NFAT Signaling Cascade Muscle Cell Differentiation Positive Regulation Of NFAT Protein Import Into Nucleus Inositol Phosphate-mediated Signaling Muscle Structure Development Cell Junction Assembly Actin Filament-based Process Cell Activation Actin-myosin Filament Sliding Focal Adhesion Assembly Muscle Filament Sliding Positive Regulation Of Transcription Factor Import Into Nucleus Actin-mediated Cell Contraction Adherens Junction Assembly Cell Development Cell-substrate Junction Assembly Sarcomere Organization Cellular Component Assembly Exocytosis Cellular Response To Drug Actin Filament-based Movement Platelet Degranulation Myofibril Assembly Transition Between Fast And Slow Fiber Cell Adhesion Adherens Junction Organization Regulation Of Transcription Factor Import Into Nucleus Calcium-mediated Signaling Positive Regulation Of Protein Import Into Nucleus Secretion By Cell Positive Regulation Of Nucleocytoplasmic Transport Positive Regulation Of Protein Localization To Nucleus Actomyosin Structure Organization Positive Regulation Of Cardiac Muscle Hypertrophy In Response To Stress Actin Cytoskeleton Organization Second-messenger-mediated Signaling Secretion Sarcomerogenesis Detection Of Muscle Stretch Skeletal Muscle Myosin Thick Filament Assembly Positive Regulation Of Intracellular Protein Transport Protein Localization To Tight Junction Regulation Of Cardiac Muscle Hypertrophy In Response To Stress Regulation Of Protein Import Into Nucleus Cell-matrix Adhesion Positive Regulation Of Transport
Tagcloud ?		actinin aligned bigenic calcineurin cardiomyopathy constituted disk disks flag gross hcm hemizygous hypertrophic hypertrophy i246m jnk54 lentiviral likewise luc mal myoz2 myozenin nfatc pp2b quantifying rcan1 s48p transgene unsettled
Tagcloud (Difference) ?		actinin aligned bigenic calcineurin cardiomyopathy constituted disk disks flag gross hcm hemizygous hypertrophic hypertrophy i246m jnk54 lentiviral likewise luc mal myoz2 myozenin nfatc pp2b quantifying rcan1 s48p transgene unsettled
Tagcloud (Intersection) ?