PANK4 and CDK20

Number of citations of the paper that reports this interaction (PMID 18508765)
7

Data Source:
BioGRID (two hybrid)

		PANK4	CDK20
Gene Name		pantothenate kinase 4	cyclin-dependent kinase 20
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm	Nucleus Cytoplasm Cilium
	Molecular Function	Pantothenate Kinase Activity ATP Binding	Cyclin-dependent Protein Serine/threonine Kinase Activity Protein Binding ATP Binding
	Biological Process	Coenzyme A Biosynthetic Process Phosphorylation	Protein Phosphorylation Cell Cycle Multicellular Organismal Development Cell Division Regulation Of Cell Cycle
Pathways		Metabolism of vitamins and cofactors Defective CD320 causes methylmalonic aciduria Defective GIF causes intrinsic factor deficiency Vitamin B5 (pantothenate) metabolism Defective LMBRD1 causes methylmalonic aciduria and homocystinuria type cblF Defective HLCS causes multiple carboxylase deficiency Defective MMAB causes methylmalonic aciduria type cblB Defective BTD causes biotidinase deficiency Defective MMACHC causes methylmalonic aciduria and homocystinuria type cblC Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD Defective MTR causes methylmalonic aciduria and homocystinuria type cblG Defective MMAA causes methylmalonic aciduria type cblA Defective MTRR causes methylmalonic aciduria and homocystinuria type cblE Defective CUBN causes hereditary megaloblastic anemia 1 Defective AMN causes hereditary megaloblastic anemia 1 Defective MUT causes methylmalonic aciduria mut type Metabolism of water-soluble vitamins and cofactors Defects in biotin (Btn) metabolism Coenzyme A biosynthesis Defective TCN2 causes hereditary megaloblastic anemia Defects in cobalamin (B12) metabolism Defects in vitamin and cofactor metabolism
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)
Protein-Protein Interactions		2 interactors: CDK20 PEA15	8 interactors: CCNH CDK2 CSNK2B GTF2IRD1 GTF2IRD2 ICK PANK4 PPP5C
Entrez ID		55229	23552
HPRD ID		07313	13010
Ensembl ID		ENSG00000157881	ENSG00000156345
Uniprot IDs		E9PHT6 Q9NVE7	Q8IZL9
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Glucose Import Negative Regulation Of Glucose Transport Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Cell Cycle Response To Morphine Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Regulation Of Glucose Import	Mitotic Cell Cycle Phosphate-containing Compound Metabolic Process Phosphorylation Protein Phosphorylation Cell Cycle G2/M Transition Of Mitotic Cell Cycle DNA Repair Transition Between Slow And Fast Fiber Nucleobase-containing Compound Metabolic Process Cellular Metabolic Process Mitotic Cell Cycle Process G1/S Transition Of Mitotic Cell Cycle Heterocycle Metabolic Process Positive Regulation Of DNA-dependent DNA Replication Initiation Cellular Aromatic Compound Metabolic Process Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Cellular Protein Modification Process Cellular Response To DNA Damage Stimulus Positive Regulation Of Activin Receptor Signaling Pathway Regulation Of DNA-dependent DNA Replication Initiation Nitrogen Compound Metabolic Process Adiponectin-activated Signaling Pathway Regulation Of Cell Cycle Cellular Macromolecule Biosynthetic Process Regulation Of Skeletal Muscle Adaptation Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Macromolecule Biosynthetic Process Endothelial Tube Morphogenesis Cell Cycle Process DNA Metabolic Process Transcription, DNA-templated Cellular Response To Nitric Oxide Mitotic Nuclear Division RNA Biosynthetic Process Positive Regulation Of DNA-dependent DNA Replication Coenzyme A Biosynthetic Process Response To Nitric Oxide Nucleotide-excision Repair, DNA Damage Removal Negative Regulation Of Blood Vessel Endothelial Cell Migration Cellular Protein Metabolic Process Regulation Of Gene Silencing Regulation Of Activin Receptor Signaling Pathway Cellular Response To Reactive Nitrogen Species Coenzyme A Metabolic Process Termination Of RNA Polymerase I Transcription Transcription Elongation From RNA Polymerase I Promoter Transcription Initiation From RNA Polymerase I Promoter 7-methylguanosine MRNA Capping
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