PIH1D1 and CA4

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		PIH1D1	CA4
Gene Name		PIH1 domain containing 1	carbonic anhydrase IV
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Pre-snoRNP Complex	Rough Endoplasmic Reticulum Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Trans-Golgi Network Plasma Membrane Cell Surface Membrane Basolateral Plasma Membrane Apical Plasma Membrane Sarcoplasmic Reticulum Transport Vesicle Membrane Secretory Granule Membrane Anchored Component Of External Side Of Plasma Membrane Brush Border Membrane Sarcolemma Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	Protein Binding	Carbonate Dehydratase Activity Protein Binding Zinc Ion Binding
	Biological Process	Box C/D SnoRNP Assembly Epithelial Cell Differentiation	One-carbon Metabolic Process Bicarbonate Transport Response To Drug Small Molecule Metabolic Process Organ Development Response To Steroid Hormone
Pathways			O2/CO2 exchange in erythrocytes Erythrocytes take up carbon dioxide and release oxygen Erythrocytes take up oxygen and release carbon dioxide Reversible hydration of carbon dioxide
Drugs			Methyclothiazide Topiramate Ethoxzolamide Bendroflumethiazide Benzthiazide Cyclothiazide Methazolamide Hydroflumethiazide Acetazolamide Dorzolamide Chlorothiazide Zonisamide Hydrochlorothiazide Trichlormethiazide Dichlorphenamide Brinzolamide Ellagic Acid
Diseases
GWAS
Protein-Protein Interactions		7 interactors: CA4 FBL MAPK6 RBPMS RUVBL1 RUVBL2 TSC22D4	5 interactors: PIH1D1 PRDX2 SLC4A1 SLC4A3 SLC4A4
Entrez ID		55011	762
HPRD ID		07938	00261
Ensembl ID		ENSG00000104872	ENSG00000167434
Uniprot IDs		Q9NWS0	P22748 Q6FHI7
PDB IDs			1ZNC 3F7B 3F7U 3FW3
Enriched GO Terms of Interacting Partners?		Histone H2A Acetylation Histone H4 Acetylation Histone Modification DNA Duplex Unwinding DNA Geometric Change Histone Glutamine Methylation Histone Acetylation Internal Peptidyl-lysine Acetylation Chromatin Modification Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Peptidyl-glutamine Methylation Protein Acetylation RNA Metabolic Process Negative Regulation Of Estrogen Receptor Binding Transcriptional Activation By Promoter-enhancer Looping Chromatin Organization SnoRNA Metabolic Process Chromatin Remodeling Establishment Of Protein Localization To Chromatin DNA Recombination Negative Regulation Of Receptor Binding Peptidyl-lysine Modification Chromosome Organization Transcription, DNA-templated DNA Conformation Change Cellular Metabolic Process RNA Biosynthetic Process Protein Localization To Chromatin Nucleobase-containing Compound Metabolic Process Positive Regulation Of SMAD Protein Import Into Nucleus Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of SMAD Protein Import Into Nucleus Cellular Response To Estradiol Stimulus Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Histone Acetylation Positive Regulation Of Peptidyl-lysine Acetylation Positive Regulation Of Protein Acetylation Response To Steroid Hormone CENP-A Containing Nucleosome Assembly Cellular Protein Modification Process Cellular Response To Estrogen Stimulus Protein Localization To Chromosome Nitrogen Compound Metabolic Process Bicarbonate Transport Histone Exchange DNA Replication-independent Nucleosome Assembly Gene Expression DNA Repair	Bicarbonate Transport Regulation Of Intracellular PH Regulation Of Cellular PH Regulation Of PH Inorganic Anion Transport Anion Transmembrane Transport Organic Anion Transport Cellular Cation Homeostasis Cellular Ion Homeostasis Cellular Chemical Homeostasis Ion Homeostasis Anion Transport Chloride Transmembrane Transport Cellular Homeostasis Chloride Transport Chemical Homeostasis Box C/D SnoRNP Assembly Ion Transmembrane Transport Homeostatic Process Transmembrane Transport Ion Transport Hydrogen Peroxide Catabolic Process Removal Of Superoxide Radicals Cellular Response To Superoxide Response To Superoxide Response To Oxygen Radical Hydrogen Peroxide Metabolic Process Superoxide Metabolic Process Cellular Response To Reactive Oxygen Species
Tagcloud ?		atpases biochemistry chaperone ck2 client cochaperones connection connects consisting depends hsp90 mediates metazoa pi3 polymerases r2tp rpap3 rvb1 rvb2 simultaneously snornps spagh structural tah1 tel2 tti1 tti2 ttt	adrenal adrenalectomy adx alteration animals autoradiography ca1 decreased dentate hippocampus histochemistry hormones hybridization igf influenced insulin level like long mrna noted receptor receptors regions situ studied suggesting term vitro
Tagcloud (Difference) ?		atpases biochemistry chaperone ck2 client cochaperones connection connects consisting depends hsp90 mediates metazoa pi3 polymerases r2tp rpap3 rvb1 rvb2 simultaneously snornps spagh structural tah1 tel2 tti1 tti2 ttt	adrenal adrenalectomy adx alteration animals autoradiography ca1 decreased dentate hippocampus histochemistry hormones hybridization igf influenced insulin level like long mrna noted receptor receptors regions situ studied suggesting term vitro
Tagcloud (Intersection) ?