TMEM132A and MEGF10

Number of citations of the paper that reports this interaction (PMID 12421765)
28

Data Source:
HPRD (two hybrid)

		TMEM132A	MEGF10
Gene Name		transmembrane protein 132A	multiple EGF-like-domains 10
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Membrane Integral Component Of Membrane Extracellular Vesicular Exosome	Phagocytic Cup Integral Component Of Membrane Basolateral Plasma Membrane Cell Projection
	Molecular Function	Molecular_function
	Biological Process	Biological_process	Skeletal Muscle Satellite Cell Activation Skeletal Muscle Satellite Cell Differentiation Skeletal Muscle Satellite Cell Proliferation Homotypic Cell-cell Adhesion Recognition Of Apoptotic Cell Regulation Of Skeletal Muscle Tissue Development Regulation Of Muscle Cell Differentiation Muscle Cell Development
Pathways
Drugs
Diseases
GWAS			Alzheimer's disease (cognitive decline) ( 23535033)
Protein-Protein Interactions		4 interactors: GSK3B HSPA5 MEGF10 UBC	22 interactors: AARS2 ALMS1 AP2M1 ARHGAP32 BAHD1 CADPS2 CEP57 CUL7 DHX16 GRB10 HDAC4 ITSN2 KIAA1598 MCF2L2 RANBP10 SART3 SCAPER SNRNP200 TAOK2 TMEM132A VWA8 ZNFX1
Entrez ID		54972	84466
HPRD ID		11034	14384
Ensembl ID		ENSG00000006118	ENSG00000145794
Uniprot IDs		Q24JP5	Q96KG7
PDB IDs
Enriched GO Terms of Interacting Partners?		ER Overload Response Glycogen Metabolic Process Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Cellular Response To Cytokine Stimulus Polysaccharide Metabolic Process Response To Cytokine Positive Regulation Of Protein Phosphorylation Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Protein Kinase Activity ER-nucleus Signaling Pathway Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Kinase Activity Positive Regulation Of Canonical Wnt Signaling Pathway Skeletal Muscle Satellite Cell Proliferation Regulation Of Protein Folding In Endoplasmic Reticulum Positive Regulation Of Phosphorylation Positive Regulation Of Protein Ubiquitination Energy Reserve Metabolic Process Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Positive Regulation Of Protein Modification Process Negative Regulation Of Apoptotic Process Negative Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Programmed Cell Death Positive Regulation Of Cellular Protein Catabolic Process Positive Regulation Of Wnt Signaling Pathway Response To Endoplasmic Reticulum Stress Negative Regulation Of Cell Death Epidermal Growth Factor Receptor Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Circadian Rhythm Negative Regulation Of Type B Pancreatic Cell Development Cerebellum Structural Organization Skeletal Muscle Cell Proliferation Skeletal Muscle Satellite Cell Activation Superior Temporal Gyrus Development Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Protein Phosphorylation Cellular Response To Fibroblast Growth Factor Stimulus Negative Regulation Of Signal Transduction Response To Fibroblast Growth Factor Negative Regulation Of Wnt Signaling Pathway Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Ubiquitination Re-entry Into Mitotic Cell Cycle Negative Regulation Of Neuron Maturation Neurotrophin TRK Receptor Signaling Pathway Negative Regulation Of Signaling Positive Regulation Of Protein Catabolic Process	Organelle Organization Cellular Component Assembly Positive Regulation Of Metabolic Process MRNA Splicing, Via Spliceosome Positive Regulation Of Histone Deubiquitination Mitochondrial Alanyl-tRNA Aminoacylation RNA Splicing, Via Transesterification Reactions Positive Regulation Of Catalytic Activity Positive Regulation Of Hydrolase Activity Cellular Macromolecular Complex Assembly Regulation Of Generation Of Precursor Metabolites And Energy Cis Assembly Of Pre-catalytic Spliceosome
Tagcloud ?			adhere adopt ap2 ap50 associating autoimmunity ced cerebellum clathrin clearing coated colocalized corpses deeper dishes elucidating engulfment flat immunoblot irregular mirrored mosaic nematode ortholog pits stellate ubiquitinated unusually vacuoles
Tagcloud (Difference) ?			adhere adopt ap2 ap50 associating autoimmunity ced cerebellum clathrin clearing coated colocalized corpses deeper dishes elucidating engulfment flat immunoblot irregular mirrored mosaic nematode ortholog pits stellate ubiquitinated unusually vacuoles
Tagcloud (Intersection) ?