ARL15 and B4GALT3

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ARL15	B4GALT3
Gene Name		ADP-ribosylation factor-like 15	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Intracellular Extracellular Vesicular Exosome	Golgi Membrane Cytoplasm Golgi Apparatus Integral Component Of Membrane Golgi Cisterna Membrane Extracellular Vesicular Exosome
	Molecular Function	Molecular_function GTP Binding	Beta-N-acetylglucosaminylglycopeptide Beta-1,4-galactosyltransferase Activity N-acetyllactosamine Synthase Activity Galactosyltransferase Activity Metal Ion Binding
	Biological Process	Small GTPase Mediated Signal Transduction Biological_process	Carbohydrate Metabolic Process Pathogenesis Keratan Sulfate Biosynthetic Process Protein N-linked Glycosylation Via Asparagine Glycosaminoglycan Metabolic Process Keratan Sulfate Metabolic Process Post-translational Protein Modification Cellular Protein Metabolic Process Small Molecule Metabolic Process
Pathways			Keratan sulfate/keratin metabolism MPS I - Hurler syndrome MPS IX - Natowicz syndrome Glycosaminoglycan metabolism Defective MGAT2 causes MGAT2-CDG (CDG-2a) N-Glycan antennae elongation Defective CHST14 causes EDS, musculocontractural type N-glycan antennae elongation in the medial/trans-Golgi Myoclonic epilepsy of Lafora MPS IIID - Sanfilippo syndrome D Defective CHST6 causes MCDC1 Glycogen storage diseases Keratan sulfate biosynthesis Defective ALG2 causes ALG2-CDG (CDG-1i) Diseases associated with glycosaminoglycan metabolism Mucopolysaccharidoses Defective ALG3 causes ALG3-CDG (CDG-1d) Post-translational protein modification Defective EXT2 causes exostoses 2 Asparagine N-linked glycosylation MPS IV - Morquio syndrome A Defective MPDU1 causes MPDU1-CDG (CDG-1f) Metabolism of carbohydrates Diseases associated with N-glycosylation of proteins MPS VI - Maroteaux-Lamy syndrome MPS IIIB - Sanfilippo syndrome B Diseases of glycosylation Defective B4GALT7 causes EDS, progeroid type Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS) Defective SLC26A2 causes chondrodysplasias Transport to the Golgi and subsequent modification Defective ALG1 causes ALG1-CDG (CDG-1k) Defective MOGS causes MOGS-CDG (CDG-2b) Defective B4GALT1 causes B4GALT1-CDG (CDG-2d) Defective ALG9 causes ALG9-CDG (CDG-1l) Defective PAPSS2 causes SEMD-PA Defective MAN1B1 causes MRT15 MPS IIIA - Sanfilippo syndrome A Defective ALG11 causes ALG11-CDG (CDG-1p) MPS IIIC - Sanfilippo syndrome C Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2 MPS II - Hunter syndrome Defective CHST3 causes SEDCJD Defective B3GAT3 causes JDSSDHD Defective EXT1 causes exostoses 1, TRPS2 and CHDS Defective B4GALT1 causes B4GALT1-CDG (CDG-2d) Defective RFT1 causes RFT1-CDG (CDG-1n) Defective ALG6 causes ALG6-CDG (CDG-1c) Defective ALG8 causes ALG8-CDG (CDG-1h) Defective ALG12 causes ALG12-CDG (CDG-1g) Defective CHSY1 causes TPBS MPS IV - Morquio syndrome B MPS VII - Sly syndrome
Drugs
Diseases
GWAS		Adiponectin levels ( 20011104 22479202) HDL cholesterol ( 20686565)
Protein-Protein Interactions		13 interactors: B4GALT3 CCDC90B CRMP1 FUNDC2 GAPDH GRIPAP1 PDE6D PTN RPL8 TFG TUBB2A UBR1 UNC119	3 interactors: ARL15 SAT1 SURF2
Entrez ID		54622	8703
HPRD ID		12471	04929
Ensembl ID		ENSG00000185305	ENSG00000158850
Uniprot IDs		Q9NXU5	A8K5Z0 O60512
PDB IDs
Enriched GO Terms of Interacting Partners?			Spermidine Acetylation Putrescine Catabolic Process Oxalate Transport 3'-phosphoadenosine 5'-phosphosulfate Biosynthetic Process Polyamine Catabolic Process Neurotransmitter Uptake 3'-phosphoadenosine 5'-phosphosulfate Metabolic Process Polyamine Biosynthetic Process Amine Biosynthetic Process Polyamine Metabolic Process Sulfate Transmembrane Transport Sulfate Transport Neutral Amino Acid Transport
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