PELO and HBS1L

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		PELO	HBS1L
Gene Name		pelota homolog (Drosophila)	HBS1-like translational GTPase
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm	Membrane Extracellular Vesicular Exosome
	Molecular Function	Endonuclease Activity Metal Ion Binding	Translation Elongation Factor Activity GTPase Activity GTP Binding
	Biological Process	Cell Cycle Cell Proliferation Chromosome Organization Cell Division Nuclear-transcribed MRNA Catabolic Process, Non-stop Decay Nuclear-transcribed MRNA Catabolic Process, No-go Decay RNA Surveillance Nucleic Acid Phosphodiester Bond Hydrolysis	Translation Translational Elongation Signal Transduction
Pathways
Drugs
Diseases
GWAS		Presence of antiphospholipid antibodies ( 23509613) Response to platinum-based agents ( 22020760)	Beta thalassemia/hemoglobin E disease ( 20183929) HbA2 levels ( 23043469) Hematocrit ( 19862010) Hematological and biochemical traits ( 20139978) Hematological parameters ( 19820697) Hematology traits ( 23263863 19853236) Mean corpuscular hemoglobin ( 23263863 20139978 19862010) Mean corpuscular hemoglobin concentration ( 23263863 20139978) Mean corpuscular volume ( 23263863 20139978 19862010) Mean platelet volume ( 22423221) Other erythrocyte phenotypes ( 19862010) Platelet counts ( 22139419 20139978) Red blood cell count ( 20139978) Red blood cell traits ( 20927387 23222517) White blood cell count ( 20139978) White blood cell types ( 21738478)
Protein-Protein Interactions		2 interactors: HBS1L PRMT6	5 interactors: APP PELO SRPK1 SRPK2 UBE2G2
Entrez ID		53918	10767
HPRD ID		09309	06582
Ensembl ID			ENSG00000112339
Uniprot IDs		Q9BRX2	D9YZV0 Q9Y450
PDB IDs		1X52
Enriched GO Terms of Interacting Partners?		Histone H3-R2 Methylation Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine Histone H4-R3 Methylation Peptidyl-arginine N-methylation Histone Arginine Methylation Peptidyl-arginine Methylation	MRNA Metabolic Process Positive Regulation Of Viral Genome Replication Negative Regulation Of Viral Genome Replication MRNA Processing Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Viral Genome Replication Positive Regulation Of Viral Process Negative Regulation Of Viral Process Regulation Of MRNA Processing RNA Processing Regulation Of RNA Splicing Nuclear-transcribed MRNA Catabolic Process, Non-stop Decay Nuclear Speck Organization Nucleus Organization Innate Immune Response Synaptic Growth At Neuromuscular Junction Regulation Of Viral Process Collateral Sprouting In Absence Of Injury Nuclear-transcribed MRNA Catabolic Process, No-go Decay Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Positive Regulation Of Cell Cycle Immune Response RNA Metabolic Process Cellular Protein Modification Process Protein Phosphorylation Defense Response RNA Surveillance Neuron Remodeling Sperm Chromatin Condensation RNA Splicing Cellular Copper Ion Homeostasis Phosphorylation Copper Ion Homeostasis Suckling Behavior Cellular Protein Metabolic Process Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Nucleobase-containing Compound Metabolic Process Spermatid Nucleus Differentiation Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Immune System Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Mating Behavior Endoplasmic Reticulum Calcium Ion Homeostasis RNA Polyadenylation
Tagcloud ?		acp1 adaptor attenuates attracting binds characterization composed deregulated dozen existence extensively hax1 inhibiting initiate interacting largely negatively p85 phosphatidylinositol pi3k plethora proteomic recruitment reveal signalling thereby transduction uncharacterized ywhaz	10p14 2p16 3p24 6q23 8q24 eomes eomesodermin european gwas gwass haematopoiesis hl hla hodgkin identifies inherited insight intergenic localizes loci mapping maps meta myb perform rs3806624 rs7745098 susceptibility totalling
Tagcloud (Difference) ?		acp1 adaptor attenuates attracting binds characterization composed deregulated dozen existence extensively hax1 inhibiting initiate interacting largely negatively p85 phosphatidylinositol pi3k plethora proteomic recruitment reveal signalling thereby transduction uncharacterized ywhaz	10p14 2p16 3p24 6q23 8q24 eomes eomesodermin european gwas gwass haematopoiesis hl hla hodgkin identifies inherited insight intergenic localizes loci mapping maps meta myb perform rs3806624 rs7745098 susceptibility totalling
Tagcloud (Intersection) ?