PLS3 and ATXN2

Number of citations of the paper that reports this interaction (PMID 16115810)
21

Data Source:
HPRD (in vivo, two hybrid)

		PLS3	ATXN2
Gene Name		plastin 3	ataxin 2
Image
Gene Ontology Annotations	Cellular Component	Cytoplasm	Nucleoplasm Cytoplasm Golgi Apparatus Trans-Golgi Network Polysome Cytoplasmic Stress Granule Membrane Ribonucleoprotein Complex Perinuclear Region Of Cytoplasm
	Molecular Function	Actin Binding Calcium Ion Binding	RNA Binding Epidermal Growth Factor Receptor Binding Protein Binding Protein C-terminus Binding Poly(A) RNA Binding
	Biological Process	Bone Development	Negative Regulation Of Receptor Internalization Regulation Of Translation RNA Metabolic Process Cerebellar Purkinje Cell Differentiation Cytoplasmic MRNA Processing Body Assembly Stress Granule Assembly Negative Regulation Of Multicellular Organism Growth Neuron Projection Morphogenesis Homeostasis Of Number Of Cells RNA Transport Neuromuscular Process
Pathways
Drugs
Diseases
GWAS			Beta-2 microglubulin plasma levels ( 23417110) Blood pressure ( 21909110) Celiac disease ( 18311140) Chronic kidney disease ( 20383146) Diastolic blood pressure ( 19430483) Hematocrit ( 19862010) Hypothyroidism ( 22493691) Red blood cell traits ( 23222517) Retinal vascular caliber ( 21060863) Urate levels ( 23263486)
Protein-Protein Interactions		2 interactors: APP ATXN2	19 interactors: ACTN1 ACTN2 ATXN1 BAG6 BIN1 CHGB GFI1B GOLGA6L5P IDH3B KIAA1279 LCP1 NCOA4 PABPC1 PLS3 RBFOX1 SH3GL2 SH3GL3 TDRD7 ZNRD1
Entrez ID		5358	6311
HPRD ID		02133	03307
Ensembl ID		ENSG00000102024	ENSG00000204842
Uniprot IDs		B4DGB4 B4DPW9 B7Z6M1 P13797	Q99700
PDB IDs		1AOA 1WJO	3KTR
Enriched GO Terms of Interacting Partners?		Regulation Of Multicellular Organism Growth Neuromuscular Process Regulation Of Translation Regulation Of Developmental Growth Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Posttranscriptional Regulation Of Gene Expression Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Regulation Of Growth Neuron Remodeling Neuron Projection Morphogenesis Negative Regulation Of Receptor Internalization Cytoplasmic MRNA Processing Body Assembly Brain Development Cerebellar Purkinje Cell Differentiation Head Development Neuron Projection Development Cell Projection Morphogenesis Stress Granule Assembly Cell Part Morphogenesis Cerebellar Purkinje Cell Layer Morphogenesis Cellular Copper Ion Homeostasis Negative Regulation Of Multicellular Organism Growth Negative Regulation Of Receptor-mediated Endocytosis Neuron Development Central Nervous System Development Copper Ion Homeostasis Suckling Behavior Cell Morphogenesis Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Cerebellar Cortex Formation Neuron Differentiation Cell Projection Organization Neurological System Process Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Cell Differentiation In Hindbrain Regulation Of Receptor Internalization Mating Behavior Cerebellar Purkinje Cell Layer Development Endoplasmic Reticulum Calcium Ion Homeostasis RNA Polyadenylation Neuron Recognition Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Homeostatic Process Cerebellar Cortex Morphogenesis	System Development Multicellular Organismal Development Anatomical Structure Development Focal Adhesion Assembly Developmental Process Adherens Junction Assembly Cell-substrate Junction Assembly Actin Filament Bundle Assembly Regulation Of Metabolic Process Platelet Degranulation Lipid Tube Assembly Adherens Junction Organization
Tagcloud ?			accumulations als amyotrophic basophilic c9orf72 causative cohorts colocalization cord expansion expansions fused ggggcc granules hexanucleotide highlights inclusions indicative motor neuron pabp paralysis polyglutamine proteomic repeat sarcoma spinal tdp transactive
Tagcloud (Difference) ?			accumulations als amyotrophic basophilic c9orf72 causative cohorts colocalization cord expansion expansions fused ggggcc granules hexanucleotide highlights inclusions indicative motor neuron pabp paralysis polyglutamine proteomic repeat sarcoma spinal tdp transactive
Tagcloud (Intersection) ?