PKM and EGLN3

  • Number of citations of the paper that reports this interaction (PMID 21620138)
  • 118
  • Data Source:
  • BioGRID (affinity chromatography technology, pull down)

PKM

EGLN3

Gene Name pyruvate kinase, muscle egl-9 family hypoxia-inducible factor 3
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 35 interactors: ANXA7 APP ARAF CDK4 CDKN1A EGLN3 EXOSC5 GRB7 HERC1 HIF1A LMO7 LNX1 MDM2 MYOC NAGK NDRG1 NXT2 OLFM2 PAX8 PIN1 POLE2 RAF1 RAP1B RCC1 RELA RPP14 SHBG SMN1 SORBS2 TERF1 TINF2 TK1 TRIM63 UCHL5 YWHAQ 22 interactors: ABI2 ADRB2 ATF4 EFHC2 EPAS1 FOXJ2 HIF1A HIF3A IKBKG MAPK1 MAPK6 MAPK7 NCAPH2 OS9 PKM PRPF19 REL SERTAD1 SIAH2 SQSTM1 TTC23L WDR83
Entrez ID 5315 112399
HPRD ID 01529 06972
Ensembl ID ENSG00000067225 ENSG00000129521
Uniprot IDs B4DNK4 P14618 Q9H6Z9
PDB IDs 1T5A 1ZJH 3BJF 3BJT 3G2G 3GQY 3GR4 3H6O 3ME3 3SRD 3SRF 3SRH 3U2Z 4B2D 4FXF 4FXJ 4G1N 4JPG
Enriched GO Terms of Interacting Partners?
Tagcloud ?
acutely  amplitudes  applications  aspartate  blockade  ca1  changing  channel  clamp  coapplication  combinations  consequence  currents  heterodimeric  hippocampal  inside  mg2  nmda  nr1a  nr2a  nr2b  opening  patch  patches  potentiated  potentiation  probability  sensitivities  voltage 
altering  avenue  cyclin  d1  deubiquitinase  egln1  egln2  foxo  foxo3a  hif  hydroxylases  hydroxylate  hydroxylation  insights  leads  pharmacologically  prevents  prolyl  promotes  promoting  proteasomal  regulate  repress  stability  suppresses  thereby  turn  usp9x 
Tagcloud (Difference) ?
acutely  amplitudes  applications  aspartate  blockade  ca1  changing  channel  clamp  coapplication  combinations  consequence  currents  heterodimeric  hippocampal  inside  mg2  nmda  nr1a  nr2a  nr2b  opening  patch  patches  potentiated  potentiation  probability  sensitivities  voltage 
altering  avenue  cyclin  d1  deubiquitinase  egln1  egln2  foxo  foxo3a  hif  hydroxylases  hydroxylate  hydroxylation  insights  leads  pharmacologically  prevents  prolyl  promotes  promoting  proteasomal  regulate  repress  stability  suppresses  thereby  turn  usp9x 
Tagcloud (Intersection) ?