PITX1 and MGAT5B

Number of citations of the paper that reports this interaction (PMID 24722188)
1

Data Source:
BioGRID (two hybrid)

		PITX1	MGAT5B
Gene Name		paired-like homeodomain 1	mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Transcription Factor Complex Nucleolus Cytoplasm	Golgi Membrane Integral Component Of Membrane
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription RNA Polymerase II Transcription Factor Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription	Protein Binding Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase Activity Metal Ion Binding
	Biological Process	Skeletal System Development Transcription, DNA-templated Anatomical Structure Morphogenesis Branchiomeric Skeletal Muscle Development Pituitary Gland Development Embryonic Hindlimb Morphogenesis Positive Regulation Of Transcription From RNA Polymerase II Promoter Myoblast Fate Commitment Cartilage Development	Protein N-linked Glycosylation
Pathways
Drugs
Diseases
GWAS		Bulimia nervosa ( 23568457) Colorectal cancer ( 23263487) Height ( 20881960 23563607 18391951) Immune response to anthrax vaccine ( 22658931) Testicular germ cell tumor ( 23666240)	Cannabis use (initiation) ( 22823124) Cardiac repolarization ( 22683750)
Protein-Protein Interactions		24 interactors: ALG13 C1orf94 CDX4 DVL3 EGR1 HGS IPO13 LZTS2 MAGED1 MGAT5B NEUROD1 NR5A1 PLSCR1 POU1F1 PRR20A RBPMS RFX6 RHOXF2 RNF31 SMARCA2 SPAG8 TRIM23 UPF2 ZBTB32	21 interactors: C20orf195 CAMK2B CREB5 DMRT3 EIF4ENIF1 FAM83A HOXA1 KLHL38 KRTAP12-2 KRTAP19-5 KRTAP26-1 MDFI OTX1 PITX1 PLSCR1 PTGER3 RBPMS STK16 TRIP13 TXNDC5 VAC14
Entrez ID		5307	146664
HPRD ID		03688	14392
Ensembl ID		ENSG00000069011	ENSG00000167889
Uniprot IDs		P78337	Q3V5L5
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Gene Expression Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Positive Regulation Of Cellular Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Nuclear Transport Regulation Of Metabolic Process Transcription, DNA-templated Cellular Macromolecule Biosynthetic Process RNA Biosynthetic Process Pancreatic A Cell Differentiation Macromolecule Biosynthetic Process Regulation Of Signaling RNA Metabolic Process Regulation Of Signal Transduction Gene Expression Nucleocytoplasmic Transport Organ Development Negative Regulation Of JAK-STAT Cascade Enteroendocrine Cell Differentiation Negative Regulation Of Cell Proliferation Negative Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Transcription, DNA-templated Cytoplasmic Transport Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process System Development Positive Regulation Of Kidney Development Negative Regulation Of Transcription From RNA Polymerase II Promoter Multicellular Organismal Aging Negative Regulation Of Wnt Signaling Pathway Glandular Epithelial Cell Differentiation Negative Regulation Of Gene Expression Pancreatic Epsilon Cell Differentiation Positive Regulation Of Glomerular Metanephric Mesangial Cell Proliferation Pancreatic D Cell Differentiation Nucleobase-containing Compound Metabolic Process Negative Regulation Of Biosynthetic Process Regulation Of Canonical Wnt Signaling Pathway	Transcription, DNA-templated RNA Biosynthetic Process Transcription From RNA Polymerase II Promoter RNA Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Gene Expression Regulation Of RNA Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription, DNA-templated Positive Regulation Of Cellular Metabolic Process Cellular Metabolic Process Nucleobase-containing Compound Metabolic Process Positive Regulation Of Transcription, DNA-templated Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression Regulation Of Metabolic Process Cellular Nitrogen Compound Metabolic Process Pattern Specification Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Acute-phase Response Nitrogen Compound Metabolic Process Positive Regulation Of Metabolic Process Regulation Of Cellular Process Embryonic Morphogenesis Abducens Nerve Formation Optokinetic Behavior Inhibitory G-protein Coupled Receptor Phosphorylation Embryonic Organ Morphogenesis Acute Inflammatory Response Facial Nucleus Development Activation Of Meiosis Involved In Egg Activation Diencephalon Development Inner Ear Morphogenesis Positive Regulation Of DNA Topoisomerase (ATP-hydrolyzing) Activity Rhombomere 4 Development Branchiomeric Skeletal Muscle Development Semicircular Canal Formation Rhombomere 3 Development Rhombomere 5 Development Activation Of Meiosis Fever Generation
Tagcloud ?		17beta 3x0 3x20 antide buserelin diarylpropionitrile dpn egr1 erb esr1 esr2 gnrh gnrhr gonadotroph lhb microinjected microinjections oestradiol oestrogenic orchestrated ovariectomised pituitaries ppt propyl pulsatile pulses pyrazole stimulations triol
Tagcloud (Difference) ?		17beta 3x0 3x20 antide buserelin diarylpropionitrile dpn egr1 erb esr1 esr2 gnrh gnrhr gonadotroph lhb microinjected microinjections oestradiol oestrogenic orchestrated ovariectomised pituitaries ppt propyl pulsatile pulses pyrazole stimulations triol
Tagcloud (Intersection) ?