PIK3CA and IRS4

  • Number of citations of the paper that reports this interaction (PMID 11912194)
  • 7
  • Data Source:
  • HPRD (in vivo)

PIK3CA

IRS4

Gene Name phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha insulin receptor substrate 4
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 43 interactors: ADAP1 AMBP APLP2 APPL1 ATPIF1 ATR DDX5 DNAJB6 FASLG FTL GABRB1 GNAQ GRIN2B HRAS IL3 IRS2 IRS4 ITIH1 KRAS LCK MRAS NEDD9 NRAS PDE4D PDGFRB PIK3R1 PIK3R3 PRKCD RASD2 RASGRP3 RPS20 RPS6KB1 SGK1 SH3KBP1 SLC9A3R1 SLC9A3R2 SMAD2 SMAD3 SQSTM1 STAT1 TICAM1 UFD1L VARS2 17 interactors: CRK CRKL EGFR ERBB2 GRB2 IGF1R MTNR1A MTNR1B NISCH PIK3CA PIK3R1 PRKCZ PTPN11 PTPN6 SOCS6 SOCS7 YWHAG
Entrez ID 5290 8471
HPRD ID 01382 04620
Ensembl ID ENSG00000133124
Uniprot IDs P42336 O14654
PDB IDs 2ENQ 2RD0 3HHM 3HIZ 3ZIM
Enriched GO Terms of Interacting Partners?
Tagcloud ?
amplified  biomarker  e542k  e545d  e545k  embedded  fixed  formalin  h1047l  h1047r  homolog  metastatic  namely  next  oncogenic  paraffin  phospho  phosphoinositol  pi3k  pras40thr246  proline  pten  reflect  refractory  respond  retrospectively  tensin  trastuzumab  unlikely 
arg35  arhg5  cbl  cblb  del  digested  downscaled  doxycycline  dyn2  errfi  flp  hek293  hsp71  hsp7c  input  l747  optimisation  pc9  ptpra  purifications  quantities  retroviral  s752  sos1  sos2  tagged  tap  usb3b  wipf2 
Tagcloud (Difference) ?
amplified  biomarker  e542k  e545d  e545k  embedded  fixed  formalin  h1047l  h1047r  homolog  metastatic  namely  next  oncogenic  paraffin  phospho  phosphoinositol  pi3k  pras40thr246  proline  pten  reflect  refractory  respond  retrospectively  tensin  trastuzumab  unlikely 
arg35  arhg5  cbl  cblb  del  digested  downscaled  doxycycline  dyn2  errfi  flp  hek293  hsp71  hsp7c  input  l747  optimisation  pc9  ptpra  purifications  quantities  retroviral  s752  sos1  sos2  tagged  tap  usb3b  wipf2 
Tagcloud (Intersection) ?