PHKB and HNRNPC

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PHKB	HNRNPC
Gene Name		phosphorylase kinase, beta	heterogeneous nuclear ribonucleoprotein C (C1/C2)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Plasma Membrane Phosphorylase Kinase Complex	Nuclear Chromatin Nucleus Nucleoplasm Spliceosomal Complex Cytosol Membrane Protein Complex Extracellular Vesicular Exosome Catalytic Step 2 Spliceosome
	Molecular Function	Hydrolase Activity, Hydrolyzing O-glycosyl Compounds Phosphorylase Kinase Activity Protein Binding Calmodulin Binding	Nucleotide Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding RNA Binding MRNA 3'-UTR Binding Protein Binding Poly(U) RNA Binding Nucleosomal DNA Binding Identical Protein Binding Poly(A) RNA Binding
	Biological Process	Carbohydrate Metabolic Process Glycogen Metabolic Process Glycogen Catabolic Process Glucose Metabolic Process Generation Of Precursor Metabolites And Energy Protein Phosphorylation Pathogenesis Small Molecule Metabolic Process	MRNA Splicing, Via Spliceosome Osteoblast Differentiation RNA Splicing Gene Expression ATP-dependent Chromatin Remodeling 3'-UTR-mediated MRNA Stabilization
Pathways		Glucose metabolism Glycogen breakdown (glycogenolysis) Myoclonic epilepsy of Lafora Glycogen storage diseases Metabolism of carbohydrates	Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS			Bipolar disorder ( 21738484)
Protein-Protein Interactions		3 interactors: C20orf27 CAMK2B HNRNPC	48 interactors: AP1M1 BARD1 BRCA1 BRCA2 BRIP1 BTRC CCDC85B CDKN2A CELF1 CSNK1A1 CSNK2A1 CSNK2A2 DHX9 EPS8 ERG FAS FXR2 GRB2 HNRNPD IL7R KHDRBS3 KPNA2 KPNA3 KPNA4 KRAS LMO2 LMO3 PALB2 PDGFB PHKB PIN1 PRKDC PTBP2 RAD51 RALY RALYL RBM41 SDCBP SF3B2 SMARCD1 SREK1 SRPK2 SUMO1 SUMO1P1 UBE2I YWHAQ ZFYVE26 ZNF581
Entrez ID		5257	3183
HPRD ID		01407	01243
Ensembl ID		ENSG00000102893	ENSG00000092199
Uniprot IDs		Q93100	P07910
PDB IDs			1TXP 1WF2 3LN4
Enriched GO Terms of Interacting Partners?		Inhibitory G-protein Coupled Receptor Phosphorylation Activation Of Meiosis Involved In Egg Activation Activation Of Meiosis Regulation Of Synaptic Transmission, Cholinergic Regulation Of Skeletal Muscle Adaptation 3'-UTR-mediated MRNA Stabilization Regulation Of Synapse Structural Plasticity Positive Regulation Of Dendritic Spine Morphogenesis Positive Regulation Of Synapse Maturation Desensitization Of G-protein Coupled Receptor Protein Signaling Pathway Positive Regulation Of Meiotic Nuclear Division Egg Activation Regulation Of Synapse Maturation Positive Regulation Of Dendritic Spine Development MRNA Stabilization Regulation Of Cellular Response To Heat Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Dendritic Spine Morphogenesis Positive Regulation Of Dendrite Morphogenesis Regulation Of Meiosis Regulation Of Dendritic Spine Development Regulation Of Meiotic Cell Cycle Regulation Of MRNA Stability Regulation Of RNA Stability Regulation Of Neuronal Synaptic Plasticity Response To Cadmium Ion Positive Regulation Of Dendrite Development Cellular Response To Heat ATP-dependent Chromatin Remodeling Regulation Of Dendrite Morphogenesis	Nucleobase-containing Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression Regulation Of Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Cell Cycle Process Nitrogen Compound Metabolic Process Double-strand Break Repair Via Homologous Recombination Recombinational Repair Cellular Response To Stimulus Cell Cycle Double-strand Break Repair Negative Regulation Of Cellular Metabolic Process Regulation Of RNA Metabolic Process Positive Regulation Of Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing RNA Splicing, Via Transesterification Reactions Cellular Metabolic Process Regulation Of Cell Cycle Cellular Response To Organic Substance MRNA Processing DNA Repair Cellular Response To Cytokine Stimulus Regulation Of Cellular Process Response To Stimulus Positive Regulation Of Signal Transduction Cellular Response To DNA Damage Stimulus Cellular Response To Stress DNA Metabolic Process Regulation Of Cell Cycle Process Negative Regulation Of Gene Expression DNA Recombination Response To Cytokine Regulation Of Protein Metabolic Process MRNA Metabolic Process Response To Organic Substance Regulation Of Cellular Component Organization Response To Ionizing Radiation Regulation Of Transcription, DNA-templated Regulation Of Cellular Protein Metabolic Process Developmental Process Positive Regulation Of Cellular Metabolic Process NLS-bearing Protein Import Into Nucleus RNA Processing Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Mitotic Cell Cycle
Tagcloud ?			17th 2d appreciation coordinately coupling d deep dihydroxyvitamin entitled epigenome exerts expanded extra fine hormones issue linking locations microrna ribonucleoprotein special splicing steroid transcriptionally tuning vdr vdre vitamin workshop
Tagcloud (Difference) ?			17th 2d appreciation coordinately coupling d deep dihydroxyvitamin entitled epigenome exerts expanded extra fine hormones issue linking locations microrna ribonucleoprotein special splicing steroid transcriptionally tuning vdr vdre vitamin workshop
Tagcloud (Intersection) ?