PFKL and KRTAP4-12

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PFKL	KRTAP4-12
Gene Name		phosphofructokinase, liver	keratin associated protein 4-12
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol 6-phosphofructokinase Complex Membrane Extracellular Vesicular Exosome	Keratin Filament
	Molecular Function	6-phosphofructokinase Activity Protein Binding ATP Binding Kinase Binding Identical Protein Binding Metal Ion Binding Fructose Binding Fructose-6-phosphate Binding	Protein Binding
	Biological Process	Carbohydrate Metabolic Process Fructose 6-phosphate Metabolic Process Glucose Metabolic Process Glycolytic Process Pathogenesis Response To Glucose Fructose 1,6-bisphosphate Metabolic Process Small Molecule Metabolic Process Negative Regulation Of Insulin Secretion Carbohydrate Phosphorylation Protein Oligomerization Protein Homotetramerization
Pathways		Glucose metabolism Myoclonic epilepsy of Lafora Glycogen storage diseases Glycolysis Metabolism of carbohydrates
Drugs
Diseases
GWAS		Rheumatoid arthritis ( 21505073)
Protein-Protein Interactions		12 interactors: APP ATN1 COPS6 GTPBP3 KRTAP10-7 KRTAP4-12 KRTAP5-9 MYD88 PFKM PRPF40A TESK1 YWHAQ	107 interactors: ADAMTSL4 ALPP AQP1 ATG12 ATN1 BAHD1 BEX2 C10orf62 C19orf66 CATSPER1 CBX2 CCDC116 CCDC185 CCNK CDC42EP1 CHCHD3 CHIC2 CLDN2 CNNM3 CNTFR COL8A1 CRCT1 CREB5 CRY1 DBF4B DLK2 EIF4E2 FAM107A FAM27E3 FAM76B FBXL18 FBXW5 GLRX3 GNE GPATCH2L GPRIN2 GRAP2 HHEX HOXA1 HOXB9 IFI30 ILF3 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP26-1 KRTAP3-2 KRTAP5-6 KRTAP5-9 KRTAP9-2 LCE1B LCE2D LCE3E LCE4A LINGO1 LNX1 MAPKBP1 MEOX2 MRPL4 NOTCH2NL NPDC1 NUDT18 NUFIP2 OTX1 PCSK5 PDGFRB PFKL PHLDA1 PLSCR1 PLSCR4 PNKP PRKAB2 PRR13 QPRT RERE RPS28 SLC25A10 SLC25A6 SMCP SPATA3 SPG7 SPRY2 TAP1 TBC1D16 TBC1D23 TCEB3B THAP10 THAP7 TOP3B TXNDC5 ZBTB16 ZNF165 ZNF20 ZNF250 ZNF408 ZNF415 ZNF417 ZNF426 ZNF439 ZNF440 ZNF581 ZNF638 ZNF655 ZNF764 ZSCAN26
Entrez ID		5211	83755
HPRD ID		01385	13941
Ensembl ID		ENSG00000141959	ENSG00000213416
Uniprot IDs		P17858 Q7L2M7	Q9BQ66
PDB IDs
Enriched GO Terms of Interacting Partners?			Macromolecule Biosynthetic Process Cellular Macromolecule Biosynthetic Process RNA Biosynthetic Process Transcription, DNA-templated Biosynthetic Process Gene Expression RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nitrogen Compound Metabolic Process Regulation Of Gene Expression Regulation Of Transcription, DNA-templated Regulation Of Nitrogen Compound Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Cellular Metabolic Process Regulation Of RNA Metabolic Process Keratinization Anterior/posterior Pattern Specification Regulation Of Cellular Process Regulation Of Metabolic Process Cellular Process Keratinocyte Differentiation Embryo Development Phospholipid Scrambling Metanephric Glomerulus Vasculature Development Pattern Specification Process Metanephric Glomerulus Development Epidermal Cell Differentiation Epidermis Development Mitochondrion Organization Metabolic Process Forebrain Morphogenesis Transcription From RNA Polymerase II Promoter Glomerulus Vasculature Development Multicellular Organismal Development Organic Anion Transport Inner Ear Development Cell Migration Involved In Coronary Angiogenesis Hepatic Duct Development Abducens Nerve Formation Metanephric Mesenchymal Cell Migration Transepithelial Water Transport Renin Secretion Into Blood Stream Metanephric Descending Thin Limb Development DGDP Catabolic Process Metanephric Proximal Straight Tubule Development Metanephric Proximal Convoluted Tubule Segment 2 Development
Tagcloud ?		aerobic ambiguous biogenesis biomass cd147 contributed differing export facilitated finger glut1 glycolysis glycoprotein hcc lactate mct1 mediators metabolism nuclease p53r2 pgc1alpha reprogrammed reprogramming rnai supplies systematically tfam transmembrane warburg
Tagcloud (Difference) ?		aerobic ambiguous biogenesis biomass cd147 contributed differing export facilitated finger glut1 glycolysis glycoprotein hcc lactate mct1 mediators metabolism nuclease p53r2 pgc1alpha reprogrammed reprogramming rnai supplies systematically tfam transmembrane warburg
Tagcloud (Intersection) ?