ZAK and SMARCB1

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		ZAK	SMARCB1
Gene Name		sterile alpha motif and leucine zipper containing kinase AZK	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm	Nuclear Chromatin XY Body Nucleus Nucleoplasm Nucleolus SWI/SNF Complex Protein Complex NpBAF Complex NBAF Complex
	Molecular Function	Magnesium Ion Binding Protein Serine/threonine Kinase Activity MAP Kinase Kinase Kinase Activity Protein Binding ATP Binding Poly(A) RNA Binding	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding P53 Binding Transcription Coactivator Activity Protein Binding Tat Protein Binding Nucleosomal DNA Binding
	Biological Process	Cell Cycle Checkpoint DNA Damage Checkpoint Activation Of MAPKK Activity Protein Phosphorylation Response To Stress Cytoskeleton Organization Cell Cycle Arrest Activation Of JUN Kinase Activity Cell Death Cell Proliferation Response To Radiation Cell Differentiation Intracellular Signal Transduction Positive Regulation Of Apoptotic Process	Blastocyst Hatching DNA Repair Chromatin Organization Nucleosome Disassembly Chromatin Remodeling Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Nervous System Development Negative Regulation Of Cell Proliferation DNA Integration Cell Differentiation Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate ATP-dependent Chromatin Remodeling Positive Regulation By Host Of Viral Transcription Mitotic Cell Cycle Phase Transition Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Pathways			Chromatin modifying enzymes Chromatin organization RMTs methylate histone arginines
Drugs
Diseases
GWAS			IgG glycosylation ( 23382691)
Protein-Protein Interactions		27 interactors: CCDC69 CRMP1 DDAH2 EZH2 IGHM ITSN1 MAP2K4 MAP2K6 MAP2K7 MIDN MPP1 NEDD4L RBX1 RNF19A RPS6KA5 SMARCB1 TGFBR1 UNC119 VPS33B YWHAG YWHAZ ZFP2 ZNF33A ZNF567 ZNF593 ZNF746 ZNF775	40 interactors: AKT1 APP BCL2L11 CALR CDX2 CEBPB DPF2 DPF3 GADD45G GATA1 KLF1 KMT2B KMT2C MAP1LC3B MAPK8IP2 MCPH1 MECP2 MYC NONO NR0B2 NR3C1 PDPK1 PPP1CC PPP1R15A PRMT5 RAN RB1 RELB RPS6KA5 SIN3B SMARCA4 SRC TACC2 TAF1D TP53 UBQLN4 XPO1 YEATS4 ZAK ZDHHC17
Entrez ID		51776	6598
HPRD ID		11791	03364
Ensembl ID		ENSG00000091436	ENSG00000099956
Uniprot IDs		D4Q8H0 Q9NYL2	G5E975 Q12824 Q9H836
PDB IDs
Enriched GO Terms of Interacting Partners?		Cellular Response To Sorbitol Positive Regulation Of Cell Death Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Regulation Of Phosphorylation Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway MyD88-dependent Toll-like Receptor Signaling Pathway Regulation Of Kinase Activity Regulation Of Phosphorus Metabolic Process Toll-like Receptor 4 Signaling Pathway Regulation Of Metabolic Process Positive Regulation Of Phosphorylation Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Toll-like Receptor Signaling Pathway Regulation Of Nitrogen Compound Metabolic Process Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Positive Regulation Of Protein Phosphorylation Positive Regulation Of Protein Kinase Activity Regulation Of Protein Kinase Activity Signal Transduction By Phosphorylation Regulation Of Caveolin-mediated Endocytosis Regulation Of Protein Phosphorylation Positive Regulation Of Kinase Activity Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Activation Of Innate Immune Response Regulation Of Cell Death Positive Regulation Of Transferase Activity Positive Regulation Of Protein Metabolic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Protein Modification Process Positive Regulation Of Signal Transduction Positive Regulation Of Innate Immune Response Apoptotic Process Programmed Cell Death Positive Regulation Of MAP Kinase Activity Transcription, DNA-templated Positive Regulation Of Neuron Death Cellular Response To Carbohydrate Stimulus Positive Regulation Of Metabolic Process Intracellular Signal Transduction Cell Death	Regulation Of Metabolic Process Regulation Of Gene Expression Positive Regulation Of Gene Expression Positive Regulation Of Cellular Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Gene Expression Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Gene Expression Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Cellular Biosynthetic Process Chromatin Organization Positive Regulation Of Metabolic Process Organelle Organization Transcription, DNA-templated Negative Regulation Of Biosynthetic Process RNA Biosynthetic Process Chromatin Modification Regulation Of Cell Cycle Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Protein Metabolic Process Chromosome Organization Regulation Of Cellular Process RNA Metabolic Process Positive Regulation Of Cellular Protein Metabolic Process Organ Development Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Transcription From RNA Polymerase II Promoter Cell Differentiation System Development Regulation Of Signaling Developmental Process Positive Regulation Of Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process Multicellular Organismal Development Negative Regulation Of Signal Transduction Regulation Of Phosphorylation Anatomical Structure Development Regulation Of Organelle Organization Regulation Of Signal Transduction Negative Regulation Of Signaling Regulation Of Phosphorus Metabolic Process
Tagcloud ?		adipogenic arresting associative ccpg1 chek chondrogenesis chondrogenic dedifferentiated dedifferentiation deriving dhcr24 dst g0s2 genechip hmga2 kat2 map2k6 maybe mll5 motivate msc osteogenesis prerequisites rassf4 rgs2 sesn3 transdifferentiate transdifferentiation unipotent	abnormality arid1a coinactivation copyright fish frame harboring heterozygous infancy insights malignancies missense monoploid mrts pbrm1 protected remodeling reserved rhabdoid rights screened sense snf subunits swi trisomy truncating
Tagcloud (Difference) ?		adipogenic arresting associative ccpg1 chek chondrogenesis chondrogenic dedifferentiated dedifferentiation deriving dhcr24 dst g0s2 genechip hmga2 kat2 map2k6 maybe mll5 motivate msc osteogenesis prerequisites rassf4 rgs2 sesn3 transdifferentiate transdifferentiation unipotent	abnormality arid1a coinactivation copyright fish frame harboring heterozygous infancy insights malignancies missense monoploid mrts pbrm1 protected remodeling reserved rhabdoid rights screened sense snf subunits swi trisomy truncating
Tagcloud (Intersection) ?