MPC1 and MAGED1

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		MPC1	MAGED1
Gene Name		mitochondrial pyruvate carrier 1	melanoma antigen family D, 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cellular_component Mitochondrion Mitochondrial Inner Membrane Integral Component Of Membrane	Chromatin Nucleus Cytoplasm Plasma Membrane Protein Complex
	Molecular Function	Molecular_function Pyruvate Transmembrane Transporter Activity	Transcription Coactivator Activity Protein Binding
	Biological Process	Pyruvate Metabolic Process Mitochondrial Pyruvate Transport Biological_process Cellular Metabolic Process Small Molecule Metabolic Process Pyruvate Transmembrane Transport	Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Circadian Regulation Of Gene Expression Regulation Of Circadian Rhythm Regulation Of Apoptotic Process Positive Regulation Of Apoptotic Process Positive Regulation Of MAP Kinase Activity Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Neurotrophin TRK Receptor Signaling Pathway Negative Regulation Of Epithelial Cell Proliferation Positive Regulation Of Branching Involved In Ureteric Bud Morphogenesis Apoptotic Signaling Pathway Positive Regulation Of Apoptotic Signaling Pathway
Pathways		Pyruvate metabolism Pyruvate metabolism and Citric Acid (TCA) cycle The citric acid (TCA) cycle and respiratory electron transport	Signalling by NGF Cell death signalling via NRAGE, NRIF and NADE NRAGE signals death through JNK Programmed Cell Death p75 NTR receptor-mediated signalling Role of DCC in regulating apoptosis Extrinsic Pathway
Drugs
Diseases
GWAS
Protein-Protein Interactions		3 interactors: ACTC1 GABARAP MAGED1	49 interactors: AKAP9 BAG3 BHLHE40 BIRC8 BRCA2 C1orf94 CA8 CCDC33 DAB1 DLX4 DLX5 EIF3J EIF4E2 EP300 GPR135 HIVEP1 KPNA2 KRTAP19-5 MAPK3 MDFI MEOX2 MPC1 MSX2 NGFR NUMBL PITX1 PJA1 PJA2 PLK1 PRKAB2 RBFOX1 RBFOX2 RBM23 RBPMS RFX1 RHOXF2 ROR2 SIRT7 SMAP2 SNRPC TFG TRAF4 TRIM28 TTC23 TTC32 TUBA4A UNC5A XIAP ZNF488
Entrez ID		51660	9500
HPRD ID		07091	02202
Ensembl ID		ENSG00000060762	ENSG00000179222
Uniprot IDs		Q5TI65 Q9Y5U8	Q9Y5V3
PDB IDs
Enriched GO Terms of Interacting Partners?		Apoptotic Process Programmed Cell Death Cell Death Death Apoptotic Signaling Pathway Skeletal Muscle Thin Filament Assembly Skeletal Myofibril Assembly Organelle Assembly Positive Regulation Of Branching Involved In Ureteric Bud Morphogenesis Regulation Of Branching Involved In Ureteric Bud Morphogenesis Nucleophagy Cardiac Myofibril Assembly Mitochondrion Degradation Muscle Filament Sliding Actin-myosin Filament Sliding	Regulation Of Metabolic Process Cellular Metabolic Process Regulation Of Gene Expression Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Cellular Process Gene Expression Negative Regulation Of Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process RNA Metabolic Process Regulation Of RNA Metabolic Process Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Gene Expression Negative Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Transcription, DNA-templated Positive Regulation Of Cellular Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Binding Transcription, DNA-templated Metabolic Process Signal Transduction Negative Regulation Of Transcription From RNA Polymerase II Promoter Organ Development Cellular Response To Stimulus Positive Regulation Of Signal Transduction RNA Biosynthetic Process Nucleobase-containing Compound Metabolic Process Cell Death Death Regulation Of Protein Metabolic Process Multicellular Organismal Development Cellular Macromolecule Biosynthetic Process Heterocycle Metabolic Process Signaling Cellular Aromatic Compound Metabolic Process Regulation Of Cellular Protein Metabolic Process Embryo Development Radial Glia Guided Migration Of Purkinje Cell Cellular Process Macromolecule Biosynthetic Process Apoptotic Signaling Pathway Cell Morphogenesis Involved In Differentiation Cell Communication Positive Regulation Of Metabolic Process System Development Apoptotic Process Response To Stimulus
Tagcloud ?		1q12 bmi1 concentrates deacetylation eed ezh2 heritable heterochromatin hmtase homologs hpc hpc2 hph k9 m33 methyltransferase multimeric observe pcg pericentromeric polycomb relocalization repress repression ring1 suv39h1 utilizes vertebrate xpc2	allelic analytical coexpression coordinator datasets esrp2 exemplifies fgfr2 gbp1 glud2 illustrates impairs indels landscape mad2l1bp mtap overlaid principle proof r353q revealing signatures slc30a8 splicing substitution tbnc tnbc tpp1 transcriptome
Tagcloud (Difference) ?		1q12 bmi1 concentrates deacetylation eed ezh2 heritable heterochromatin hmtase homologs hpc hpc2 hph k9 m33 methyltransferase multimeric observe pcg pericentromeric polycomb relocalization repress repression ring1 suv39h1 utilizes vertebrate xpc2	allelic analytical coexpression coordinator datasets esrp2 exemplifies fgfr2 gbp1 glud2 illustrates impairs indels landscape mad2l1bp mtap overlaid principle proof r353q revealing signatures slc30a8 splicing substitution tbnc tnbc tpp1 transcriptome
Tagcloud (Intersection) ?