CHMP3 and CHMP4A

Number of citations of the paper that reports this interaction (PMID 14505570)
292

Data Source:
BioGRID (two hybrid)

		CHMP3	CHMP4A
Gene Name		charged multivesicular body protein 3	charged multivesicular body protein 4A
Image
Gene Ontology Annotations	Cellular Component	Cytosol Late Endosome Membrane Extracellular Vesicular Exosome	ESCRT III Complex Nucleus Cytoplasm Cytosol Cytoplasmic Side Of Plasma Membrane Midbody Cytoplasmic Vesicle Membrane Late Endosome Membrane Extracellular Vesicular Exosome
	Molecular Function	Protein Binding	Protein Binding Lipid Binding Identical Protein Binding Protein Homodimerization Activity ATPase Binding
	Biological Process	Cell Separation After Cytokinesis Apoptotic Process Nucleus Organization Vacuolar Transport Mitotic Metaphase Plate Congression Regulation Of Centrosome Duplication Protein Transport Viral Process Endosomal Transport Viral Life Cycle Regulation Of Viral Process Membrane Organization Regulation Of Mitotic Spindle Assembly Positive Regulation Of Viral Release From Host Cell Regulation Of Exosomal Secretion	Cell Separation After Cytokinesis Posttranslational Protein Targeting To Membrane Membrane Budding Nucleus Organization Vacuolar Transport Mitotic Metaphase Plate Congression Viral Process Endosomal Transport Viral Life Cycle Viral Budding Via Host ESCRT Complex Protein Homooligomerization Membrane Organization Membrane Tubulation Negative Regulation Of Neuron Death Negative Regulation Of Autophagic Vacuole Assembly
Pathways		HIV Life Cycle Budding and maturation of HIV virion HIV Infection Endosomal Sorting Complex Required For Transport (ESCRT) Late Phase of HIV Life Cycle	HIV Life Cycle Budding and maturation of HIV virion HIV Infection Endosomal Sorting Complex Required For Transport (ESCRT) Late Phase of HIV Life Cycle
Drugs
Diseases
GWAS
Protein-Protein Interactions		12 interactors: APP CHMP2A CHMP2B CHMP4A CHMP4B IGFBP7 RAB11A SMAD1 SMAD5 STAMBP TNPO3 VAV2	12 interactors: CC2D1A CDK13 CHMP3 CHMP4B CHMP4C CHMP5 CHMP6 PDCD6IP STAMBP SYT17 TTC19 VPS4A
Entrez ID		51652	29082
HPRD ID		15650	16597
Ensembl ID		ENSG00000115561	ENSG00000254505
Uniprot IDs		Q9Y3E7	Q14D22 Q9BY43
PDB IDs		2GD5 2XZE 3FRT 3FRV	3C3O
Enriched GO Terms of Interacting Partners?		Viral Budding Via Host ESCRT Complex Mitotic Metaphase Plate Congression Metaphase Plate Congression Viral Budding Establishment Of Chromosome Localization Cell Separation After Cytokinesis Mitotic Sister Chromatid Segregation Virion Assembly Sister Chromatid Segregation Regulation Of Mitotic Spindle Assembly Regulation Of Spindle Assembly Cell Division Regulation Of Mitotic Spindle Organization Endosomal Transport Vacuolar Transport Membrane Budding Chromosome Segregation Mitotic Nuclear Division Nucleus Organization Establishment Of Organelle Localization Mitotic Cell Cycle Process Negative Regulation Of Autophagic Vacuole Assembly Mitotic Cell Cycle Regulation Of Mitotic Cell Cycle Regulation Of Centrosome Duplication Organelle Localization Regulation Of Centrosome Cycle Vesicle-mediated Transport Viral Life Cycle Osteoblast Fate Commitment Regulation Of Cell Cycle Process Intracellular Transport Vesicle Organization Cell Cycle Process Posttranslational Protein Targeting To Membrane Positive Regulation Of Viral Release From Host Cell Regulation Of Cellular Component Organization Establishment Of Localization In Cell Negative Regulation Of Macroautophagy Establishment Of Protein Localization To Organelle Cell Cycle Regulation Of Autophagic Vacuole Assembly Protein Transport Regulation Of Mitotic Nuclear Division Establishment Of Protein Localization Regulation Of Vacuole Organization Membrane Organization Cellular Response To BMP Stimulus Regulation Of Microtubule Cytoskeleton Organization Regulation Of Cell Death	Cell Separation After Cytokinesis Cell Division Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Mitotic Metaphase Plate Congression Viral Life Cycle Metaphase Plate Congression Regulation Of Centrosome Duplication Establishment Of Chromosome Localization Regulation Of Centrosome Cycle Viral Process Vacuolar Transport Mitotic Sister Chromatid Segregation Endosomal Transport Sister Chromatid Segregation Regulation Of Cell Cycle Process Nucleus Organization Viral Budding Via Host ESCRT Complex Positive Regulation Of Viral Release From Host Cell Regulation Of Mitotic Spindle Assembly Regulation Of Microtubule Cytoskeleton Organization Viral Budding Regulation Of Spindle Assembly Regulation Of Microtubule-based Process Regulation Of Mitotic Spindle Organization Membrane Organization Chromosome Segregation Regulation Of Cell Cycle Regulation Of Cell Division Regulation Of Viral Release From Host Cell Virion Assembly Cell Cycle Process Mitotic Nuclear Division Regulation Of Mitotic Nuclear Division Establishment Of Organelle Localization Mitotic Cell Cycle Process Mitotic Cell Cycle Cell Cycle Organelle Localization Protein Transport Establishment Of Protein Localization Regulation Of Organelle Organization Regulation Of Cytoskeleton Organization Abscission Positive Regulation Of Viral Process Membrane Budding Negative Regulation Of Cytokinesis Protein Localization Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Establishment Of Localization In Cell
Tagcloud ?		degradative depletion dramatic eap30 egfrs endocytic endocytosed endosomal endosomes equally escrt golgi internalization intraluminal lysosomes m6prs machinery multivesicular mves recycling redistribution reflecting sorting stam tgn trafficking tsg101 vps22 vps24
Tagcloud (Difference) ?		degradative depletion dramatic eap30 egfrs endocytic endocytosed endosomal endosomes equally escrt golgi internalization intraluminal lysosomes m6prs machinery multivesicular mves recycling redistribution reflecting sorting stam tgn trafficking tsg101 vps22 vps24
Tagcloud (Intersection) ?