PPHLN1 and SNCAIP

Number of citations of the paper that reports this interaction (PMID 19730898)
1

Data Source:
BioGRID (two hybrid)

		PPHLN1	SNCAIP
Gene Name		periphilin 1	synuclein, alpha interacting protein
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Golgi Apparatus Intracellular Membrane-bounded Organelle	Cytoplasm Synaptic Vesicle Presynaptic Membrane Neuronal Cell Body
	Molecular Function	Poly(A) RNA Binding	Protein Binding Ubiquitin Protein Ligase Binding Identical Protein Binding
	Biological Process	Keratinization	Dopamine Metabolic Process Regulation Of Neurotransmitter Secretion Regulation Of Inclusion Body Assembly
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		20 interactors: APP BCL2L1 BRCA1 CASP5 CCDC57 CDC37 CDK6 MTUS2 NAGK PAXIP1 PPL SEPT8 SNCAIP SQSTM1 TGM2 TOMM20 TP53BP2 TSGA10 UFD1L VIM	19 interactors: AES AGXT C11orf58 GET4 GSK3B NUB1 NUDT21 PARK2 PINK1 PPHLN1 PPP1CA PTN RNF19A SEPT4 SH2D3C SIAH1 SIAH2 SNCA UBB
Entrez ID		51535	9627
HPRD ID		10488	04804
Ensembl ID		ENSG00000134283	ENSG00000064692
Uniprot IDs		B7Z8L1 E9PAX8 F8W6A0 Q8NEY8	Q9NVG1 Q9Y6H5
PDB IDs			2KES
Enriched GO Terms of Interacting Partners?		Response To Ionizing Radiation Apoptotic Process Programmed Cell Death Cell Death Death Response To Radiation Positive Regulation Of Histone H3-K4 Methylation Regulation Of Cell Cycle Positive Regulation Of Histone Acetylation Signal Transduction By P53 Class Mediator Developmental Process Regulation Of Histone H3-K4 Methylation Response To Abiotic Stimulus Positive Regulation Of Peptidyl-lysine Acetylation Apoptotic Signaling Pathway Organ Development Positive Regulation Of Protein Acetylation Astrocyte Development Multicellular Organismal Development Anatomical Structure Development System Development Endoplasmic Reticulum Calcium Ion Homeostasis Negative Regulation Of Cell Cycle Positive Regulation Of Histone Methylation Intrinsic Apoptotic Signaling Pathway Intracellular Receptor Signaling Pathway Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Astrocyte Differentiation Regulation Of Histone Acetylation Central Nervous System Development Positive Regulation Of Gene Expression Regulation Of Histone Methylation Neuron Apoptotic Process Positive Regulation Of Histone H4-K20 Methylation Cell Dedifferentiation Positive Regulation Of Histone H3-K36 Methylation Positive Regulation Of Histone H4-K16 Acetylation Apoptotic Process In Bone Marrow Regulation Of Signaling Neuron Death Positive Regulation Of Histone Modification Execution Phase Of Apoptosis Isopeptide Cross-linking Via N6-(L-isoglutamyl)-L-lysine Synaptic Growth At Neuromuscular Junction Positive Regulation Of Histone H3-K9 Acetylation N-acetylmannosamine Metabolic Process DNA Damage Response, Signal Transduction By P53 Class Mediator Cell Differentiation Cellular Protein Metabolic Process Signal Transduction In Response To DNA Damage	Positive Regulation Of Apoptotic Signaling Pathway Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Regulation Of Apoptotic Process Regulation Of Cell Death Positive Regulation Of Proteolysis Regulation Of Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Protein Ubiquitination Protein Modification By Small Protein Conjugation Regulation Of Generation Of Precursor Metabolites And Energy Regulation Of Protein Ubiquitination Regulation Of Proteolysis Regulation Of Dopamine Secretion Negative Regulation Of Signal Transduction Negative Regulation Of Signaling Regulation Of Signal Transduction Ubiquitin-dependent Protein Catabolic Process Dopamine Uptake Involved In Synaptic Transmission Modification-dependent Protein Catabolic Process Positive Regulation Of Signal Transduction Energy Derivation By Oxidation Of Organic Compounds Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Positive Regulation Of Protein Ubiquitination Regulation Of Protein Stability Regulation Of Synaptic Vesicle Transport Regulation Of Signaling Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Negative Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Protein Catabolic Process Positive Regulation Of Cellular Protein Catabolic Process Regulation Of Carbohydrate Metabolic Process Regulation Of Cellular Response To Oxidative Stress Positive Regulation Of Mitochondrion Organization Positive Regulation Of Cellular Protein Metabolic Process Generation Of Precursor Metabolites And Energy Glycogen Metabolic Process Negative Regulation Of Wnt Signaling Pathway Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Oxidative Stress-induced Neuron Death Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Catalytic Activity Positive Regulation Of Mitochondrial Fission Positive Regulation Of Protein Catabolic Process Positive Regulation Of Proteasomal Protein Catabolic Process Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Protein Metabolic Process
Tagcloud ?			adar colorectal contain dcaf12l2 exomes glt1d1 hot instability itga7 map1b microsatellite mrgprx4 oncogenes personalized profiling psrc1 ranbp2 respective rps6kl1 sequenced spot spots tceal6 tubb6 validated validation vegfb wbp5 zbtb2
Tagcloud (Difference) ?			adar colorectal contain dcaf12l2 exomes glt1d1 hot instability itga7 map1b microsatellite mrgprx4 oncogenes personalized profiling psrc1 ranbp2 respective rps6kl1 sequenced spot spots tceal6 tubb6 validated validation vegfb wbp5 zbtb2
Tagcloud (Intersection) ?