VGLL1 and TEAD1

Number of citations of the paper that reports this interaction (PMID 10518497)
19

Data Source:
HPRD (in vitro, in vivo, two hybrid)

		VGLL1	TEAD1
Gene Name		vestigial-like family member 1	TEA domain family member 1 (SV40 transcriptional enhancer factor)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Nucleoplasm Cytoplasm Golgi Apparatus
	Molecular Function	Transcription Coactivator Activity	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated	Regulation Of Transcription, DNA-templated Transcription Initiation From RNA Polymerase II Promoter Gene Expression Hippo Signaling
Pathways			PPARA activates gene expression Fatty acid, triacylglycerol, and ketone body metabolism Generic Transcription Pathway Metabolism of lipids and lipoproteins YAP1- and WWTR1 (TAZ)-stimulated gene expression Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
Drugs
Diseases
GWAS			Height ( 20881960)
Protein-Protein Interactions		4 interactors: TEAD1 TEAD2 TEAD3 TEAD4	17 interactors: GCAT HLA-DMB INSR MAX MEF2A MEF2BNB-MEF2B MEF2C MYH7 NCOA1 SRF TBP UBTD1 VGLL1 VGLL2 VGLL4 YAP1 ZDHHC17
Entrez ID		51442	7003
HPRD ID		06751	01802
Ensembl ID		ENSG00000102243	ENSG00000187079
Uniprot IDs		Q99990	A4FUP2 P28347 Q59EF3
PDB IDs			2HZD 3KYS
Enriched GO Terms of Interacting Partners?		Hippo Signaling Positive Regulation Of Stem Cell Maintenance Transcription Initiation From RNA Polymerase II Promoter Regulation Of Stem Cell Maintenance DNA-templated Transcription, Initiation Positive Regulation Of Stem Cell Differentiation Lateral Mesoderm Development Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription From RNA Polymerase II Promoter Notochord Development Paraxial Mesoderm Development Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Cell Development Regulation Of Transcription From RNA Polymerase II Promoter Intracellular Signal Transduction Embryonic Heart Tube Morphogenesis Embryonic Heart Tube Development Transcription, DNA-templated RNA Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Regulation Of Cell Development Positive Regulation Of Cell Differentiation Mesoderm Development RNA Metabolic Process Mesenchyme Development Embryo Development Positive Regulation Of Metabolic Process Gene Expression Heart Morphogenesis Cellular Macromolecule Biosynthetic Process Female Pregnancy Macromolecule Biosynthetic Process Embryonic Organ Morphogenesis Regulation Of Transcription, DNA-templated Regulation Of Cell Differentiation Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Epithelial Tube Morphogenesis Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Gene Expression Tube Morphogenesis Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process	Heart Morphogenesis Transcription, DNA-templated RNA Biosynthetic Process Positive Regulation Of Developmental Growth Embryonic Heart Tube Morphogenesis Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Embryonic Heart Tube Development Platelet Formation Positive Regulation Of Growth Platelet Morphogenesis Biosynthetic Process Cardiac Myofibril Assembly Primary Heart Field Specification Sinoatrial Valve Morphogenesis Regulation Of Synaptic Activity Cellular Response To Trichostatin A RNA Metabolic Process Heart Development Transcription From RNA Polymerase II Promoter Regulation Of Developmental Growth Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Nephron Tubule Epithelial Cell Differentiation Epithelial Cell Proliferation Involved In Renal Tubule Morphogenesis Muscle Cell Fate Determination Gene Expression Striated Muscle Tissue Development Regulation Of RNA Metabolic Process Muscle Tissue Development Positive Regulation Of Macromolecule Biosynthetic Process Cardiac Chamber Development Positive Regulation Of Cell Proliferation In Bone Marrow Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Macrophage Apoptotic Process Positive Regulation Of Behavioral Fear Response Positive Regulation Of Organ Growth Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Tissue Development Ventricular Cardiac Myofibril Assembly Smooth Muscle Cell Differentiation Cardiac Muscle Tissue Development Heart Looping Determination Of Heart Left/right Asymmetry Positive Regulation Of Protein Homodimerization Activity Positive Regulation Of Transcription, DNA-templated Cardiac Muscle Cell Development Embryonic Organ Development
Tagcloud ?		atlas bbox1 brca1 c6orf211 carcinomas coordinated dataset esr1 foxa1 foxc1 frozen gabrp gata3 hippo intronic luminal microarrays mirna occasionally prom1 seq slc6a14 sporadic structurally taz tcga tn vestigial yap	520d 5p biomaterial cd105 combinatorial convert converted dedifferentiation demethylation elavl2 fibroblasts gatad2b hsa ipscs lost microrna mir mscs never pluripotent safely stemness survived transfectants transfection transfections tumorigenicity turned usefulness
Tagcloud (Difference) ?		atlas bbox1 brca1 c6orf211 carcinomas coordinated dataset esr1 foxa1 foxc1 frozen gabrp gata3 hippo intronic luminal microarrays mirna occasionally prom1 seq slc6a14 sporadic structurally taz tcga tn vestigial yap	520d 5p biomaterial cd105 combinatorial convert converted dedifferentiation demethylation elavl2 fibroblasts gatad2b hsa ipscs lost microrna mir mscs never pluripotent safely stemness survived transfectants transfection transfections tumorigenicity turned usefulness
Tagcloud (Intersection) ?