HOOK1 and TBC1D7

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		HOOK1	TBC1D7
Gene Name		hook microtubule-tethering protein 1	TBC1 domain family, member 7
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Microtubule HOPS Complex FHF Complex	Cytoplasmic Membrane-bounded Vesicle Cytoplasmic Vesicle Ciliary Basal Body
	Molecular Function	Actin Binding Protein Binding Identical Protein Binding	Rab GTPase Activator Activity Protein Binding Rab GTPase Binding
	Biological Process	Endosome Organization Lysosome Organization Multicellular Organismal Development Spermatid Development Endosome To Lysosome Transport Protein Transport Early Endosome To Late Endosome Transport	Positive Regulation Of Protein Ubiquitination Negative Regulation Of TOR Signaling Positive Regulation Of Rab GTPase Activity Activation Of Rho GTPase Activity Response To Growth Factor Negative Regulation Of Cilium Assembly
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		18 interactors: AKTIP ANK3 CDC5L CDK4 FAM160A2 HOOK2 HOOK3 LMO2 SYCE1 TBC1D7 TFIP11 USP2 VPS16 VPS18 VPS39 VPS41 ZNF250 ZNF785	16 interactors: APP BLZF1 GABARAPL1 HOOK1 IKBKG KRT19 LDOC1 LZTS2 MAP1LC3A NEDD4 NEDD4L RPGRIP1 SSNA1 TRAF4 TSC1 TSC2
Entrez ID		51361	51256
HPRD ID		07428	18165
Ensembl ID		ENSG00000134709	ENSG00000145979
Uniprot IDs		Q9UJC3	Q5JPB9 Q9P0N9
PDB IDs			3QWL
Enriched GO Terms of Interacting Partners?		Endosome Organization Vacuole Organization Lysosome Organization Early Endosome To Late Endosome Transport Vacuolar Transport Endosome To Lysosome Transport Regulation Of SNARE Complex Assembly Lysosomal Transport Protein Transport Establishment Of Protein Localization Endosomal Transport Intracellular Transport Endomembrane System Organization Regulation Of Vesicle Fusion Protein Localization Vesicle-mediated Transport Establishment Of Localization In Cell Cytoplasmic Transport Cellular Localization Organelle Organization Cellular Protein Localization Intracellular Protein Transport Viral Entry Into Host Cell Entry Into Host Cell Maintenance Of Protein Location In Plasma Membrane Regulation Of Vacuole Fusion, Non-autophagic Spliceosomal Complex Disassembly Positive Regulation Of Membrane Depolarization During Cardiac Muscle Cell Action Potential Vacuole Fusion, Non-autophagic Negative Regulation Of Delayed Rectifier Potassium Channel Activity Positive Regulation Of Cell Communication By Electrical Coupling Regulation Of Protein Complex Assembly Negative Regulation Of Cilium Assembly Cell Cycle Regulation Of Vesicle-mediated Transport Interaction With Host Cellular Response To Magnesium Ion Regulation Of Membrane Depolarization During Cardiac Muscle Cell Action Potential Positive Regulation Of Mitotic Cell Cycle Cell Division Regulation Of Membrane Depolarization During Action Potential Regulation Of Organelle Organization Maintenance Of Protein Location In Cell Transport Maintenance Of Protein Location Regulation Of Cardiac Muscle Cell Action Potential Maintenance Of Location In Cell Regulation Of Delayed Rectifier Potassium Channel Activity Cell Cycle Process Circadian Rhythm	Establishment Of Localization In Cell Intracellular Transport Cytoplasmic Transport Cellular Localization Glucose Import Negative Regulation Of Sodium Ion Transport Vacuole Organization Negative Regulation Of Signal Transduction Negative Regulation Of Cell Size Negative Regulation Of Signaling Activation Of NF-kappaB-inducing Kinase Activity Regulation Of Protein Kinase Activity Nucleophagy Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Cellular Component Assembly Regulation Of Kinase Activity Positive Regulation Of NIK/NF-kappaB Signaling Regulation Of Potassium Ion Transmembrane Transporter Activity Response To Stimulus Mitochondrion Degradation Regulation Of Signal Transduction Negative Regulation Of TOR Signaling Membrane Organization Cell Communication Synapse Organization NIK/NF-kappaB Signaling Regulation Of NIK/NF-kappaB Signaling Organelle Assembly Regulation Of Protein Metabolic Process Organ Development Regulation Of Potassium Ion Transmembrane Transport Intracellular Receptor Signaling Pathway Organelle Disassembly Negative Regulation Of Insulin Receptor Signaling Pathway Protein Monoubiquitination Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Regulation Of Signaling Autophagic Vacuole Assembly Viral Process Cell Surface Receptor Signaling Pathway Lysosomal Transport Regulation Of Protein Phosphorylation Neuromuscular Junction Development Regulation Of TOR Signaling Macroautophagy Nucleocytoplasmic Transport Nuclear Transport Regulation Of Cell Junction Assembly Cellular Response To Stimulus Cell Projection Organization
Tagcloud ?		6v3 akr1c2 amongst appearing bard1 beadchip bisulfite cdf15 cobra coro2a cyrillic5 diagnostics dnajc12 humanwd illumina interrogated normalcy ntrk4 pppqr1b s100p sentrix sfrp1 tff1 timp4 top2a tp53ink1 tusc5 tuscapital unmethylated	2a akt anabolic bub2 cdc16 coimmunoprecipitated constant dephosphorylation homolog mechanistic modulator mtorc1 nutrients phosphorylates pp2a rapamycin redd1 repress represses repressor rheb ser stimulating thr tre2 tsc tsc1 tsc2 tuberous
Tagcloud (Difference) ?		6v3 akr1c2 amongst appearing bard1 beadchip bisulfite cdf15 cobra coro2a cyrillic5 diagnostics dnajc12 humanwd illumina interrogated normalcy ntrk4 pppqr1b s100p sentrix sfrp1 tff1 timp4 top2a tp53ink1 tusc5 tuscapital unmethylated	2a akt anabolic bub2 cdc16 coimmunoprecipitated constant dephosphorylation homolog mechanistic modulator mtorc1 nutrients phosphorylates pp2a rapamycin redd1 repress represses repressor rheb ser stimulating thr tre2 tsc tsc1 tsc2 tuberous
Tagcloud (Intersection) ?