WAC and RNF40

Number of citations of the paper that reports this interaction (PMID 21329877)
18

Data Source:
BioGRID (pull down)

		WAC	RNF40
Gene Name		WW domain containing adaptor with coiled-coil	ring finger protein 40, E3 ubiquitin protein ligase
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex Nuclear Speck	Ubiquitin Ligase Complex Nucleus Nucleoplasm Membrane HULC Complex Neuron Projection
	Molecular Function	RNA Polymerase II Core Binding Chromatin Binding Protein Binding	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Ligase Activity Syntaxin-1 Binding Ubiquitin Protein Ligase Binding Protein Complex Binding Protein Homodimerization Activity
	Biological Process	Transcription, DNA-templated Cellular Response To DNA Damage Stimulus Histone Monoubiquitination Positive Regulation Of Macroautophagy Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process G1 DNA Damage Checkpoint Positive Regulation Of Transcription, DNA-templated Histone H2B Conserved C-terminal Lysine Ubiquitination	Ubiquitin-dependent Protein Catabolic Process Histone Monoubiquitination Histone H2B Ubiquitination
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		22 interactors: AKAP9 APP CRKL CTD DYDC1 KLC3 KRT15 LNX1 MTUS2 NDE1 NFE2L2 POLR2A RNF20 RNF40 SYTL5 TRAF1 TRAF3IP1 TRAF3IP3 UBQLN4 VCP VCPIP1 ZDHHC17	18 interactors: AMOTL2 ATM CCDC146 CDC73 HIST2H2BE ITSN1 MSL1 NCBP1 RB1 SFR1 TRIM51 UBE2A UBE2B UBE2E1 UBE2I UBE2L6 WAC ZNF451
Entrez ID		51322	9810
HPRD ID		18291	07411
Ensembl ID		ENSG00000095787	ENSG00000103549
Uniprot IDs		Q9BTA9	A8K6K1 F8W8Z4 O75150
PDB IDs
Enriched GO Terms of Interacting Partners?		Microtubule-based Transport Protein Ubiquitination Cytoskeleton-dependent Intracellular Transport Protein Modification By Small Protein Conjugation Histone H2B Ubiquitination Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Catabolic Process Microtubule-based Movement Histone Monoubiquitination Cellular Component Assembly Histone Ubiquitination Cellular Macromolecule Catabolic Process Protein Monoubiquitination Intracellular Transport Proteolysis Axon Cargo Transport Positive Regulation Of Lys63-specific Deubiquitinase Activity Positive Regulation Of Protein K63-linked Deubiquitination Positive Regulation Of Cellular Protein Metabolic Process Cellular Protein Modification Process Synaptic Growth At Neuromuscular Junction Endoplasmic Reticulum Membrane Fusion Transcription, RNA-templated Positive Regulation Of Protein Metabolic Process Positive Regulation Of Cellular Metabolic Process Endoplasmic Reticulum Unfolded Protein Response Microtubule-based Process Regulation Of Cellular Protein Metabolic Process Collateral Sprouting In Absence Of Injury Cellular Response To Unfolded Protein Establishment Of Localization In Cell ER-nucleus Signaling Pathway Proteasomal Ubiquitin-independent Protein Catabolic Process Golgi Reassembly Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Oxidative Stress Cellular Response To Topologically Incorrect Protein Regulation Of Embryonic Development G2/M Transition Of Mitotic Cell Cycle Collateral Sprouting Axon Midline Choice Point Recognition Retrograde Protein Transport, ER To Cytosol Regulation Of Protein Metabolic Process Positive Regulation Of Protein Modification Process Response To Unfolded Protein Regulation Of Protein Deubiquitination Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process	Histone Ubiquitination Chromatin Organization Chromatin Modification Histone Modification Chromosome Organization Protein Monoubiquitination Histone H2B Ubiquitination Protein Ubiquitination Protein Modification By Small Protein Conjugation Histone Monoubiquitination Cellular Macromolecule Catabolic Process Protein Catabolic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Protein K48-linked Ubiquitination Negative Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Mitotic Sister Chromatid Separation Regulation Of Mitotic Metaphase/anaphase Transition ISG15-protein Conjugation Organelle Organization Regulation Of Proteasomal Protein Catabolic Process Regulation Of Chromosome Organization Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteasomal Protein Catabolic Process Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Mitotic Cell Cycle Regulation Of Cell Cycle Process Cell Cycle Cell Cycle Checkpoint Regulation Of Cell Cycle Phase Transition Modification-dependent Protein Catabolic Process Negative Regulation Of Cellular Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of Cell Division Proteasomal Protein Catabolic Process Regulation Of Chromosome Segregation Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Negative Regulation Of Chromosome Organization Cell Cycle Process Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Histone H2A Ubiquitination Positive Regulation Of MRNA 3'-end Processing Regulation Of MRNA 3'-end Processing Negative Regulation Of Protein Catabolic Process Cellular Protein Modification Process Regulation Of Mitotic Nuclear Division Catabolic Process Histone MRNA Metabolic Process Regulation Of G1/S Transition Of Mitotic Cell Cycle Postreplication Repair
Tagcloud ?		bd ccrd composite cooking defatted equation fitted flour gruel gsl ingredient moisture noodle noodles polynomial proximate quadratic rotatable salted sc soy swelling tapioca ve wheat wur x1 x2 x3	accessible alongside attracting deubiquitinases discoveries disrupt e3 fostering h2b h2bub1 h3k4 h3k79 ligases marking monoubiquitination parathyroid polyubiquitination ptm ptms recruiting rnf20 shed strands talk traditionally usp22 usp44 usp7 viewed
Tagcloud (Difference) ?		bd ccrd composite cooking defatted equation fitted flour gruel gsl ingredient moisture noodle noodles polynomial proximate quadratic rotatable salted sc soy swelling tapioca ve wheat wur x1 x2 x3	accessible alongside attracting deubiquitinases discoveries disrupt e3 fostering h2b h2bub1 h3k4 h3k79 ligases marking monoubiquitination parathyroid polyubiquitination ptm ptms recruiting rnf20 shed strands talk traditionally usp22 usp44 usp7 viewed
Tagcloud (Intersection) ?