CHCHD2 and TRIM54

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		CHCHD2	TRIM54
Gene Name		coiled-coil-helix-coiled-coil-helix domain containing 2	tripartite motif containing 54
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrion	Microtubule Microtubule Associated Complex Z Disc
	Molecular Function		Signal Transducer Activity Microtubule Binding Zinc Ion Binding
	Biological Process		Microtubule-based Process Negative Regulation Of Microtubule Depolymerization Signal Transduction Multicellular Organismal Development Cell Differentiation
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		12 interactors: ADAMTSL4 EHMT2 GOLGA2 IKZF3 INCA1 KRT31 KRT40 LHX4 REL TCF4 TRIM54 UBC	127 interactors: ADCY4 ALS2CR11 ARFIP2 ARHGEF5 ATXN3 ATXN3L ATXN7 BYSL C12orf49 C1orf109 C1orf216 C1QTNF2 CALM3 CARD9 CCDC102B CCDC146 CCDC28A CCDC67 CCDC87 CDK18 CDKN1A CEP57L1 CHCHD2 CKM CRADD CWF19L2 CYTH4 DCUN1D1 DNAL4 DTX2 EHHADH EIF4E2 ELMO1 ENKD1 EPM2AIP1 EXOSC5 FAM110A FAM124A FAM124B FAM161A FARS2 FBF1 FLNC GEM GMCL1 GTF2IRD2 HAUS1 ING3 INPP5J IQUB JOSD1 KDM1A KIFC3 KLHL38 KPNA2 KRT6A KRT6B KRT6C LENG1 LIN37 LMO2 LNX1 LSM2 MAPK3 MBD3 MCM7 MEAF6 MFAP1 MID2 MYO5B NGLY1 OSTF1 OTUB1 OTUB2 PIK3R3 PPP1R18 PRF1 RABGEF1 RAD23A RBM41 RCOR3 RSRC2 SCNM1 SDCBP SENP3 SH2D1B SMARCE1 SNF8 SPG21 SSX2IP STAM STRA13 TBC1D22B TCEA2 TCEB3 THOC1 TRIM55 TRIM63 TSHZ3 TTC23 UBE2D3 UBE2I UBE2U UCHL1 UCHL3 UCHL5 USHBP1 USP15 USP18 USP2 USP21 USP33 USP4 USP5 USP7 USP8 UTP14C VPS28 WDR34 WDYHV1 YOD1 ZBTB16 ZGPAT ZNF250 ZNF417 ZNF572 ZNF587
Entrez ID		51142	57159
HPRD ID		09879	05928
Ensembl ID		ENSG00000106153	ENSG00000138100
Uniprot IDs		Q9Y6H1	Q9BYV2
PDB IDs			3Q1D
Enriched GO Terms of Interacting Partners?		Regulation Of Cell Death Regulation Of Apoptotic Process Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Negative Regulation Of Transcription From RNA Polymerase II Promoter I-kappaB Kinase/NF-kappaB Signaling Glycogen Metabolic Process Polysaccharide Metabolic Process Negative Regulation Of Cell Death Regulation Of Transcription From RNA Polymerase II Promoter Medial Motor Column Neuron Differentiation Catenin Import Into Nucleus Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition Negative Regulation Of Cell Cycle Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Cellular Response To Growth Factor Stimulus Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Energy Reserve Metabolic Process Maintenance Of DNA Repeat Elements DNA Methylation On Cytosine Within A CG Sequence Positive Regulation Of Signal Transduction Glucose Metabolic Process Regulation Of Protein Binding Negative Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Gene Expression Transcription, DNA-templated Negative Regulation Of Biosynthetic Process Transcription Initiation From RNA Polymerase II Promoter Cell Cycle Negative Regulation Of Type B Pancreatic Cell Apoptotic Process Embryonic Hindgut Morphogenesis Cellular Macromolecule Biosynthetic Process RNA Biosynthetic Process Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Macromolecule Biosynthetic Process Embryonic Genitalia Morphogenesis Regulation Of Cellular Response To Growth Factor Stimulus Somatic Motor Neuron Differentiation Myoblast Fate Commitment Negative Regulation Of Wnt Signaling Pathway Developmental Process Involved In Reproduction Hexose Metabolic Process Secretory Granule Localization Histone H3-K27 Methylation DNA-templated Transcription, Initiation	Protein Deubiquitination Protein Modification By Small Protein Removal Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Protein Catabolic Process Cellular Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Cellular Macromolecule Catabolic Process Protein K48-linked Deubiquitination Protein K63-linked Deubiquitination Proteolysis Regulation Of Proteasomal Protein Catabolic Process Catabolic Process Cellular Protein Metabolic Process Regulation Of Metabolic Process Cellular Protein Modification Process Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Metabolic Process Organelle Organization Regulation Of Protein Catabolic Process Protein Metabolic Process Histone Deubiquitination RNA Metabolic Process Transcription, DNA-templated Nucleobase-containing Compound Metabolic Process Cellular Process Monoubiquitinated Protein Deubiquitination Histone Modification Gene Expression RNA Biosynthetic Process Chromatin Modification Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Cellular Process Negative Regulation Of Cellular Metabolic Process Regulation Of Proteolysis Protein Targeting To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Chromatin Organization Cellular Response To DNA Damage Stimulus Nitrogen Compound Metabolic Process Chromosome Organization Cellular Response To Heat Negative Regulation Of Cellular Protein Metabolic Process Regulation Of Nitrogen Compound Metabolic Process
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