PRLH and PRLHR

Number of citations of the paper that reports this interaction (PMID 9607765)
40

Data Source:
HPRD (in vivo, in vitro)

		PRLH	PRLHR
Gene Name		prolactin releasing hormone	prolactin releasing hormone receptor
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Cytoplasm	Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	Hormone Activity Neuropeptide Hormone Activity Prolactin-releasing Peptide Receptor Binding	G-protein Coupled Receptor Activity Neuropeptide Y Receptor Activity Protein Binding Neuropeptide Receptor Activity
	Biological Process	Tissue Homeostasis Reduction Of Food Intake In Response To Dietary Excess Energy Reserve Metabolic Process Lipid Metabolic Process G-protein Coupled Receptor Signaling Pathway Response To Glucose Response To Insulin Regulation Of Multicellular Organism Growth Fat Cell Differentiation Autonomic Nervous System Development	G-protein Coupled Receptor Signaling Pathway Neuropeptide Signaling Pathway Female Pregnancy Feeding Behavior Hormone Metabolic Process
Pathways		Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR Peptide ligand-binding receptors Class A/1 (Rhodopsin-like receptors) Metabolic disorders of biological oxidation enzymes GPCR ligand binding	Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR Peptide ligand-binding receptors Class A/1 (Rhodopsin-like receptors) Metabolic disorders of biological oxidation enzymes GPCR ligand binding
Drugs
Diseases
GWAS			Pancreatic cancer ( 22158540)
Protein-Protein Interactions		1 interactors: PRLHR	3 interactors: PICK1 PRLH SNTA1
Entrez ID		51052	2834
HPRD ID		04046	02937
Ensembl ID		ENSG00000071677	ENSG00000119973
Uniprot IDs		P81277 Q53QV7	A5JUU5 P49683
PDB IDs
Enriched GO Terms of Interacting Partners?		Neuropeptide Signaling Pathway Feeding Behavior	Regulation Of Vasoconstriction By Circulating Norepinephrine Reduction Of Food Intake In Response To Dietary Excess Negative Regulation Of Peptidyl-cysteine S-nitrosylation Regulation Of Actin Filament-based Process DNA Methylation Involved In Embryo Development Response To Nutrient Levels Dendritic Spine Maintenance Response To Extracellular Stimulus Neuronal Ion Channel Clustering Negative Regulation Of Arp2/3 Complex-mediated Actin Nucleation Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization Negative Regulation Of Actin Nucleation Long Term Synaptic Depression Response To Dietary Excess Positive Regulation Of Receptor Internalization Ventricular Cardiac Muscle Cell Action Potential Regulation Of Arp2/3 Complex-mediated Actin Nucleation Dendritic Spine Organization Regulation Of Membrane Repolarization DNA Methylation Involved In Gamete Generation Regulation Of Actin Nucleation Cellular Response To Glucose Starvation Monoamine Transport Cellular Component Maintenance Cardiac Muscle Cell Action Potential Involved In Contraction Eating Behavior Neuron Maturation Regulation Of Receptor Internalization Regulation Of Sodium Ion Transmembrane Transport Retrograde Vesicle-mediated Transport, Golgi To ER Cardiac Muscle Cell Action Potential Positive Regulation Of Receptor-mediated Endocytosis Autonomic Nervous System Development Regulation Of Cardiac Muscle Cell Contraction Protein Kinase C-activating G-protein Coupled Receptor Signaling Pathway Receptor Clustering Neuromuscular Junction Development G-protein Coupled Receptor Signaling Pathway Regulation Of Vasoconstriction DNA Methylation Negative Regulation Of Synaptic Transmission Regulation Of Sodium Ion Transport Regulation Of Heart Rate Regulation Of Cardiac Muscle Contraction Regulation Of Striated Muscle Contraction Action Potential DNA Modification Feeding Behavior Regulation Of Multicellular Organism Growth Cellular Response To Decreased Oxygen Levels
Tagcloud ?		1nm 26rfa 28nm 3mum amide amphioxus bfl branchiostoma carboxyterminal clustered ec50 ending floridae gnih gpr103 implying inserted intron introns npff npy orphan phe prepro propeptide qrfp rfa rfamide rya	accounts brown calb1 call creeping cutoffs egg eggshell empirical footprints gal gaps heterozygosity hypotheses insr lepr localizing moving nramp1 outliers permutation scanned sliding statistic subjectively sweeps tails window windows
Tagcloud (Difference) ?		1nm 26rfa 28nm 3mum amide amphioxus bfl branchiostoma carboxyterminal clustered ec50 ending floridae gnih gpr103 implying inserted intron introns npff npy orphan phe prepro propeptide qrfp rfa rfamide rya	accounts brown calb1 call creeping cutoffs egg eggshell empirical footprints gal gaps heterozygosity hypotheses insr lepr localizing moving nramp1 outliers permutation scanned sliding statistic subjectively sweeps tails window windows
Tagcloud (Intersection) ?