PCBD1 and ZNF451

Number of citations of the paper that reports this interaction (PMID 20211142)
148

Data Source:
BioGRID (two hybrid)

		PCBD1	ZNF451
Gene Name		pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha	zinc finger protein 451
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Extracellular Vesicular Exosome	Nucleus
	Molecular Function	Transcription Coactivator Activity Phenylalanine 4-monooxygenase Activity Protein Binding 4-alpha-hydroxytetrahydrobiopterin Dehydratase Activity Identical Protein Binding	DNA Binding Protein Binding Metal Ion Binding
	Biological Process	Transcription, DNA-templated L-phenylalanine Catabolic Process Tetrahydrobiopterin Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Protein Homodimerization Activity Small Molecule Metabolic Process Positive Regulation Of Transcription, DNA-templated Protein Homotetramerization Protein Heterooligomerization Oxidation-reduction Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated
Pathways		Phenylalanine and tyrosine catabolism Metabolism of amino acids and derivatives
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)
Protein-Protein Interactions		49 interactors: ACIN1 APP BRD7 CACNA1C CALCOCO1 CDK5RAP2 CEBPZ DENND4A DIP2C DVL2 DYRK1B EHMT1 FXR2 GORASP2 GTF3C3 HES4 HNF1A HNF1B HNF4A KLF13 LNX1 MIS18BP1 NFKB1 NIF3L1 NUDT18 PAH PAPOLG PCBD2 POLR3A RBL2 RPS24 SAP30 SCMH1 SMARCD1 SOWAHC SUPT5H TFF3 TIMELESS TRIM5 WDYHV1 WWP1 ZBTB25 ZNF195 ZNF202 ZNF23 ZNF263 ZNF451 ZNF567 ZNF714	23 interactors: AR CALCOCO2 CDC5L CPTP CREB1 FXR2 HTT JMJD6 KDM1A LZTR1 PCBD1 PIAS1 PIAS2 PRMT1 PRMT8 PRPF40A RAP1GDS1 RNF40 SNIP1 SUMO1 SUV39H1 UBC UBE2I
Entrez ID		5092	26036
HPRD ID		00523	10332
Ensembl ID		ENSG00000166228	ENSG00000112200
Uniprot IDs		P61457	B4DYS2 Q96JY2 Q9Y4E5
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Biosynthetic Process Regulation Of RNA Metabolic Process RNA Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression Transcription, DNA-templated Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Cellular Nitrogen Compound Metabolic Process Regulation Of RNA Biosynthetic Process Gene Expression Heterocycle Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Biosynthetic Process Cellular Metabolic Process Positive Regulation Of Transcription, DNA-templated Regulation Of Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of Gene Expression Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Biosynthetic Process Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Cellular Metabolic Process Metabolic Process Chromatin Remodeling Transcription From RNA Polymerase II Promoter Positive Regulation Of Metabolic Process Chromatin Organization Insulin Secretion Negative Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription From RNA Polymerase II Promoter Chromosome Organization Chromatin Modification Endocrine Pancreas Development Regulation Of Cellular Process Peptide Hormone Secretion Peptide Secretion Positive Regulation Of Transcription Initiation From RNA Polymerase II Promoter Cellular Process Positive Regulation Of DNA-templated Transcription, Initiation Hormone Secretion	Regulation Of Gene Expression Protein Sumoylation Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Peptidyl-lysine Modification Regulation Of RNA Metabolic Process Regulation Of Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Histone Modification Peptidyl-amino Acid Modification Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Androgen Receptor Signaling Pathway Organelle Organization RNA Metabolic Process Cellular Protein Modification Process Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Chromatin Modification Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine Protein Modification By Small Protein Conjugation Heterocycle Metabolic Process Transcription, DNA-templated Gene Expression RNA Biosynthetic Process Intracellular Receptor Signaling Pathway Cellular Nitrogen Compound Metabolic Process Intracellular Steroid Hormone Receptor Signaling Pathway Chromatin Organization Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Gene Expression Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Peptidyl-arginine N-methylation Nucleobase-containing Compound Metabolic Process Histone H4-R3 Methylation Regulation Of Innate Immune Response Diencephalon Development Regulation Of Binding Nitrogen Compound Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Metabolic Process Histone Arginine Methylation Viral Process Peptidyl-arginine Methylation Regulation Of Megakaryocyte Differentiation Positive Regulation Of Transcription, DNA-templated Rhythmic Process Regulation Of Transcription From RNA Polymerase II Promoter
Tagcloud ?			acetylation acts attenuates beta blocks bodies causes cofactor corepressor demonstrating depletion enhances functionally h3k9 inhibits interacts localized mechanistically negatively physically promoters promyelocytic recruit regulates responses smad3 taken tgf transcriptional
Tagcloud (Difference) ?			acetylation acts attenuates beta blocks bodies causes cofactor corepressor demonstrating depletion enhances functionally h3k9 inhibits interacts localized mechanistically negatively physically promoters promyelocytic recruit regulates responses smad3 taken tgf transcriptional
Tagcloud (Intersection) ?