PRDX1 and LUC7L

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		PRDX1	LUC7L
Gene Name		peroxiredoxin 1	LUC7-like (S. cerevisiae)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Nucleus Nuclear Euchromatin Nucleolus Cytoplasm Mitochondrial Matrix Peroxisomal Matrix Cytosol Melanosome Extracellular Vesicular Exosome	U1 SnRNP
	Molecular Function	Peroxidase Activity Protein Binding Thioredoxin Peroxidase Activity Heme Binding Protein Homodimerization Activity Poly(A) RNA Binding	MRNA Binding Protein Binding Identical Protein Binding RS Domain Binding
	Biological Process	Response To Reactive Oxygen Species Skeletal System Development Retina Homeostasis Cell Proliferation Removal Of Superoxide Radicals Regulation Of Stress-activated MAPK Cascade Erythrocyte Homeostasis Natural Killer Cell Mediated Cytotoxicity Regulation Of NF-kappaB Import Into Nucleus Hydrogen Peroxide Catabolic Process Oxidation-reduction Process	MRNA Splice Site Selection Negative Regulation Of Striated Muscle Tissue Development
Pathways		Detoxification of Reactive Oxygen Species
Drugs
Diseases
GWAS			Mean corpuscular hemoglobin ( 20139978)
Protein-Protein Interactions		24 interactors: ABL1 ADH5 BTRC CALM1 CLEC4G EGFR GAPDH IRF3 LUC7L MTRNR2L1 MYC MYD88 PPP2R1A PPP2R1B PRDX4 SESN1 SESN2 SH2D1B SMARCD1 SNCA TERF1 UBE3A VHL YWHAQ	11 interactors: CALM1 CHERP CTNNBL1 FAM173A FBXO25 GADD45G PRDX1 PRMT5 SRPK1 SRPK2 TCERG1
Entrez ID		5052	55692
HPRD ID		01458	08476
Ensembl ID		ENSG00000117450	ENSG00000007392
Uniprot IDs		Q06830	D3DU41 Q1W6G4 Q9NQ29
PDB IDs		2RII 3HY2
Enriched GO Terms of Interacting Partners?		Regulation Of Protein Metabolic Process Regulation Of Signal Transduction Regulation Of Apoptotic Process Regulation Of Cellular Protein Metabolic Process Regulation Of Cell Death Response To Organic Substance Regulation Of Signaling Negative Regulation Of Cellular Metabolic Process Regulation Of Oxidoreductase Activity Positive Regulation Of Apoptotic Process Negative Regulation Of Protein Metabolic Process Positive Regulation Of Programmed Cell Death Response To Stimulus Positive Regulation Of Cell Death Regulation Of Phospholipase Activity Apoptotic Process Programmed Cell Death Intracellular Signal Transduction Cellular Response To Organic Substance Cell Death Death Regulation Of Response To Reactive Oxygen Species Regulation Of Cellular Ketone Metabolic Process Peptidyl-cysteine S-nitrosylation Innate Immune Response Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Oxidoreductase Activity Response To Lipid Regulation Of Protein Stability Response To Lipopolysaccharide Developmental Process Positive Regulation Of Signal Transduction Response To Molecule Of Bacterial Origin Cellular Response To Growth Factor Stimulus Type I Interferon Biosynthetic Process Immune Response Regulation Of Immune System Process Regulation Of Intracellular Signal Transduction Regulation Of Phosphorylation Response To Growth Factor Regulation Of Cell Cycle Cellular Response To Stimulus Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Biosynthetic Process Cellular Response To Organic Cyclic Compound Regulation Of Cellular Amino Acid Metabolic Process Cellular Response To Fibroblast Growth Factor Stimulus Negative Regulation Of Phosphorylation Cell Cycle Process Response To Fibroblast Growth Factor	RNA Processing RNA Splicing MRNA Processing Positive Regulation Of Viral Genome Replication MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Negative Regulation Of Viral Genome Replication Innate Immune Response Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Viral Genome Replication Regulation Of Cell Cycle Positive Regulation Of Viral Process Nuclear Speck Organization Negative Regulation Of Viral Process Regulation Of MRNA Processing Regulation Of Transcription Factor Import Into Nucleus Regulation Of Intracellular Transport RNA Metabolic Process Regulation Of RNA Splicing Peptidyl-arginine Methylation, To Symmetrical-dimethyl Arginine Reactive Oxygen Species Metabolic Process Immune System Process Nucleus Organization Gene Expression Immune Response Defense Response Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Positive Regulation Of Cell Death Regulation Of Viral Process Regulation Of High Voltage-gated Calcium Channel Activity Regulation Of Ion Homeostasis Developmental Process Nitrogen Compound Metabolic Process Regulation Of Protein Import Into Nucleus Ribonucleoprotein Complex Assembly Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Regulation Of Stress-activated MAPK Cascade Cellular Metabolic Process Regulation Of Protein Localization To Nucleus Positive Regulation Of NFAT Protein Import Into Nucleus Positive Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Regulation Of Nucleocytoplasmic Transport Activation Of MAPKKK Activity Positive Regulation Of P38MAPK Cascade Sperm Chromatin Condensation Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Regulation Of Cell Division
Tagcloud ?		agouti camk2g cd47 chances clstn2 consonant enpp1 epha5a gad2 gria3 grin2b kif minipumps myo5a negr1 neuroplasticity ntrk2 ntrk3 ppp3r1 predecessors serotonine slc2a4 sv2b syn2 synaptogenesis synj2 therapeutical venlafaxine vlx
Tagcloud (Difference) ?		agouti camk2g cd47 chances clstn2 consonant enpp1 epha5a gad2 gria3 grin2b kif minipumps myo5a negr1 neuroplasticity ntrk2 ntrk3 ppp3r1 predecessors serotonine slc2a4 sv2b syn2 synaptogenesis synj2 therapeutical venlafaxine vlx
Tagcloud (Intersection) ?