TBC1D25 and MAP1LC3A

Number of citations of the paper that reports this interaction (PMID 22354992)
16

Data Source:
BioGRID (pull down)

		TBC1D25	MAP1LC3A
Gene Name		TBC1 domain family, member 25	microtubule-associated protein 1 light chain 3 alpha
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Autophagic Vacuole Cytoplasmic Vesicle	Pre-autophagosomal Structure Autophagic Vacuole Membrane Late Endosome Autophagic Vacuole Cytosol Microtubule Extrinsic Component Of Membrane Organelle Membrane Cytoplasmic Vesicle
	Molecular Function	Rab GTPase Activator Activity Protein Binding	Protein Binding Phospholipid Binding Microtubule Binding Phosphatidylethanolamine Binding GABA Receptor Binding
	Biological Process	Autophagy Positive Regulation Of Rab GTPase Activity Regulation Of Autophagic Vacuole Maturation	Autophagic Vacuole Assembly Mitochondrion Degradation Cellular Response To Nitrogen Starvation Nucleophagy Membrane Fusion
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		8 interactors: FEZ1 FEZ2 GABARAP GABARAPL1 GABARAPL2 MAP1LC3A MAP1LC3B RAB2A	40 interactors: AKAP13 APP ATG101 ATG13 ATG3 ATG4B ATG7 BNIP3L DVL2 EPHA7 FAM134C FUNDC1 KIF15 KXD1 MAP1A MAP1S NBR1 OPTN PIAS4 PRPF40A RABGAP1 RABGAP1L RDH12 RTKN SQSTM1 SRPK1 TBC1D1 TBC1D10A TBC1D10B TBC1D16 TBC1D17 TBC1D2 TBC1D25 TBC1D2B TBC1D5 TBC1D7 TBC1D9 TBC1D9B TNIP1 TUBA4A
Entrez ID		4943	84557
HPRD ID		08948	03144
Ensembl ID		ENSG00000068354	ENSG00000101460
Uniprot IDs		Q3MII6	Q9H492
PDB IDs			3ECI
Enriched GO Terms of Interacting Partners?		Nucleophagy Mitochondrion Degradation Organelle Disassembly Autophagic Vacuole Assembly Macroautophagy Vacuole Organization Membrane Fusion Cellular Response To Starvation Autophagy Cellular Response To Nutrient Levels Response To Starvation Cellular Response To Extracellular Stimulus Cellular Response To Nitrogen Starvation Mitochondrion Organization Response To Nutrient Levels Response To External Stimulus Response To Extracellular Stimulus Organelle Assembly Membrane Organization Cellular Response To Stimulus Cellular Response To Stress Catabolic Process Organelle Organization Cellular Component Assembly Response To Stimulus Cell Communication Response To Stress Establishment Of Localization In Cell Negative Regulation Of Macroautophagy Cellular Localization Establishment Of Mitochondrion Localization Axon Guidance Protein Transport Establishment Of Protein Localization Positive Regulation Of ATPase Activity Negative Regulation Of Autophagy Intracellular Transport Mitochondrion Localization Axonogenesis Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Regulation Of ATPase Activity Axon Development Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis	Positive Regulation Of Rab GTPase Activity Regulation Of Rab GTPase Activity Regulation Of Rab Protein Signal Transduction Autophagy Positive Regulation Of Ras GTPase Activity Regulation Of Ras Protein Signal Transduction Regulation Of Intracellular Signal Transduction Regulation Of Ras GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction Positive Regulation Of GTPase Activity Regulation Of GTPase Activity Positive Regulation Of Hydrolase Activity Regulation Of Signal Transduction Macroautophagy Response To Starvation Regulation Of Signaling Positive Regulation Of Catalytic Activity Cellular Response To Starvation Cellular Response To Nutrient Levels Regulation Of Catalytic Activity Positive Regulation Of Metabolic Process Cellular Response To Extracellular Stimulus Response To Nutrient Levels Response To Extracellular Stimulus Mitochondrion Degradation Catabolic Process Positive Regulation Of Autophagy Organelle Disassembly Autophagic Vacuole Assembly Regulation Of Metabolic Process Response To External Stimulus Intracellular Transport Retrograde Transport, Endosome To Golgi Nucleophagy Establishment Of Localization In Cell Cellular Localization Endosomal Transport Vacuole Organization Regulation Of Autophagy Cell Death Death Response To Stress Regulation Of Cellular Process Apoptotic Process Programmed Cell Death Organelle Organization Positive Regulation Of Macroautophagy Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Cellular Response To Nitrogen Starvation
Tagcloud ?			acquiring adenocarcinoma autophagy became came constitutive date demethylation egfr erlotinib escaping exposing gefitinib ie immunoreactivity necessarily neoplastic novo overcoming parental pc9 pivotal predictor pronounced restores tkis treating tumoural
Tagcloud (Difference) ?			acquiring adenocarcinoma autophagy became came constitutive date demethylation egfr erlotinib escaping exposing gefitinib ie immunoreactivity necessarily neoplastic novo overcoming parental pc9 pivotal predictor pronounced restores tkis treating tumoural
Tagcloud (Intersection) ?