NUP88 and NUP98

Number of citations of the paper that reports this interaction (PMID 12589057)
38

Data Source:
BioGRID (affinity chromatography technology, pull down)
HPRD (in vivo, in vitro)

		NUP88	NUP98
Gene Name		nucleoporin 88kDa	nucleoporin 98kDa
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nuclear Pore Nucleoplasm Cytosol	Kinetochore Nuclear Envelope Nuclear Pore Nucleoplasm Cytosol Nuclear Pore Outer Ring Nuclear Membrane Nuclear Periphery Nuclear Inclusion Body Nuclear Pore Nuclear Basket
	Molecular Function	Transporter Activity	Transporter Activity Protein Binding Structural Constituent Of Nuclear Pore Peptide Binding
	Biological Process	Mitotic Cell Cycle Carbohydrate Metabolic Process Mitotic Nuclear Envelope Disassembly Hexose Transport Pathogenesis Gene Expression Regulation Of Glucose Transport Protein Transport Glucose Transport Viral Process Viral Life Cycle Viral Transcription Cytokine-mediated Signaling Pathway Small Molecule Metabolic Process MRNA Transport Transmembrane Transport	Protein Import Into Nucleus, Docking Mitotic Cell Cycle Carbohydrate Metabolic Process DNA Replication Nucleocytoplasmic Transport Nuclear Pore Organization Mitotic Nuclear Envelope Disassembly Hexose Transport Pathogenesis Gene Expression Regulation Of Glucose Transport Glucose Transport Viral Process Viral Life Cycle Viral Transcription Cytokine-mediated Signaling Pathway Small Molecule Metabolic Process MRNA Transport Nuclear Pore Complex Assembly Transmembrane Transport
Pathways		Mitotic Prophase HIV Infection Nuclear import of Rev protein Regulatory RNA pathways Rev-mediated nuclear export of HIV RNA Nuclear Envelope Breakdown SLC-mediated transmembrane transport M Phase Influenza Life Cycle HIV Life Cycle Influenza Viral RNA Transcription and Replication Rev-mediated nuclear export of HIV RNA Myoclonic epilepsy of Lafora Glycogen storage diseases Transcriptional regulation by small RNAs Vpr-mediated nuclear import of PICs ISG15 antiviral mechanism Interferon Signaling Host Interactions of HIV factors Nuclear Pore Complex (NPC) Disassembly Regulation of Glucokinase by Glucokinase Regulatory Protein Cytokine Signaling in Immune system Interactions of Vpr with host cellular proteins Interactions of Rev with host cellular proteins Influenza Infection Hexose transport Cell Cycle, Mitotic Late Phase of HIV Life Cycle Antiviral mechanism by IFN-stimulated genes Viral Messenger RNA Synthesis Metabolism of carbohydrates Glucose transport
Drugs
Diseases
GWAS
Protein-Protein Interactions		3 interactors: CD82 NUP214 NUP98	18 interactors: APC CREBBP CSNK2A1 EP300 HDAC1 IPO5 KPNB1 NFX1 NUP133 NUP62 NUP88 NXF1 RAE1 RCC1 SEC13 TNPO1 TNPO2 TPR
Entrez ID		4927	4928
HPRD ID		03974	03012
Ensembl ID		ENSG00000108559	ENSG00000110713
Uniprot IDs		Q99567	P52948
PDB IDs			1KO6 2Q5X 2Q5Y 3MMY
Enriched GO Terms of Interacting Partners?		Mitotic Nuclear Envelope Disassembly Nuclear Envelope Disassembly Nuclear Envelope Organization Glucose Transport Hexose Transport Viral Transcription Regulation Of Glucose Transport MRNA Transport Protein Import Into Nucleus Nucleus Organization Nuclear Import Carbohydrate Transport RNA Transport RNA Localization Protein Import Protein Localization To Nucleus Viral Life Cycle Pathogenesis Nucleocytoplasmic Transport Nuclear Transport Protein Import Into Nucleus, Docking Establishment Of Protein Localization To Organelle Protein Targeting Endomembrane System Organization Cytokine-mediated Signaling Pathway Protein Localization To Organelle Nuclear Pore Complex Assembly Viral Process Cellular Response To Cytokine Stimulus Nuclear Pore Organization Mitotic Cell Cycle Process Cytoplasmic Transport Response To Cytokine Pore Complex Assembly Mitotic Cell Cycle Membrane Organization Intracellular Protein Transport Carbohydrate Metabolic Process Cell Cycle Process Protein Export From Nucleus Cell Cycle Cellular Protein Localization Protein Transport Establishment Of Protein Localization Intracellular Transport MRNA Export From Nucleus Transmembrane Transport RNA Export From Nucleus Cellular Response To Organic Substance Protein Localization	Viral Process Mitotic Cell Cycle MRNA Transport RNA Transport Nucleocytoplasmic Transport Nuclear Transport RNA Localization Mitotic Nuclear Envelope Disassembly Nuclear Envelope Disassembly Cell Cycle Mitotic Cell Cycle Process Cytoplasmic Transport Nuclear Envelope Organization Glucose Transport Hexose Transport Viral Life Cycle Viral Transcription Regulation Of Glucose Transport Cell Cycle Process Nucleus Organization Intracellular Transport Carbohydrate Transport MRNA Export From Nucleus RNA Export From Nucleus Protein Transport Organelle Organization Establishment Of Protein Localization Establishment Of Localization In Cell Pathogenesis Cytokine-mediated Signaling Pathway Gene Expression Protein Import Into Nucleus Nuclear Import N-terminal Peptidyl-lysine Acetylation Nuclear Export Regulation Of Mitotic Nuclear Division RNA Biosynthetic Process Cellular Localization Cell Surface Receptor Signaling Pathway Cellular Response To Organic Substance Cellular Response To Cytokine Stimulus Protein Localization Mitotic Spindle Checkpoint Protein Import Negative Regulation Of Chromosome Segregation Regulation Of Mitotic Sister Chromatid Separation Protein Localization To Nucleus Negative Regulation Of Mitotic Nuclear Division Spindle Checkpoint Regulation Of Mitotic Metaphase/anaphase Transition
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