NSF and PTPN9

Number of citations of the paper that reports this interaction (PMID 15322554)
26

Data Source:
HPRD (in vitro)

		NSF	PTPN9
Gene Name		N-ethylmaleimide-sensitive factor	protein tyrosine phosphatase, non-receptor type 9
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Lysosomal Membrane Golgi Stack Cytosol Plasma Membrane Postsynaptic Density Dendritic Shaft Extracellular Vesicular Exosome	Cytoplasm
	Molecular Function	Protein Binding ATP Binding ATPase Activity Syntaxin-1 Binding Rab GTPase Binding Protein Kinase Binding PDZ Domain Binding Protein Complex Binding ATPase Activity, Coupled Metal Ion Binding	Protein Tyrosine Phosphatase Activity Non-membrane Spanning Protein Tyrosine Phosphatase Activity Protein Binding
	Biological Process	Positive Regulation Of Receptor Recycling Potassium Ion Transport Exocytosis Intra-Golgi Vesicle-mediated Transport Synaptic Transmission Vesicle-mediated Transport Regulation Of Exocytosis Golgi To Plasma Membrane Protein Transport Plasma Membrane Fusion Golgi Vesicle Docking	Protein Dephosphorylation Peptidyl-tyrosine Dephosphorylation
Pathways		Trafficking of GluR2-containing AMPA receptors Glutamate Binding, Activation of AMPA Receptors and Synaptic Plasticity Trafficking of AMPA receptors Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell Transmission across Chemical Synapses
Drugs
Diseases
GWAS		Parkinson's disease ( 19915575 21812969)	Height ( 20189936)
Protein-Protein Interactions		25 interactors: ARRB1 C14orf1 CD28 DRD2 EIF3E FUNDC2 GABARAP GABARAPL2 GABBR1 GABBR2 GOSR1 GRIA2 GRIA3 KIAA1377 LUC7L2 NAPA NAPG PTPN9 RAMP3 RPLP1 STX1A STX4 STX8 USO1 VAPA	8 interactors: AGTRAP CMTM5 GHR MAL2 NSF REEP6 RTN3 STX6
Entrez ID		4905	5780
HPRD ID		03380	02864
Ensembl ID		ENSG00000073969	ENSG00000169410
Uniprot IDs		P46459	P43378
PDB IDs			2PA5 4GE2 4GE5 4GE6
Enriched GO Terms of Interacting Partners?		Membrane Fusion Membrane Organization Intracellular Transport Golgi Vesicle Transport Protein Localization Establishment Of Localization In Cell Protein Transport Synaptic Transmission Vesicle-mediated Transport Establishment Of Protein Localization Cellular Localization Cell-cell Signaling Intracellular Protein Transport Vesicle Fusion Intra-Golgi Vesicle-mediated Transport Cellular Protein Localization Neuron-neuron Synaptic Transmission Organelle Fusion Negative Regulation Of Adenylate Cyclase Activity Negative Regulation Of Lyase Activity Vesicle Organization Negative Regulation Of CAMP Biosynthetic Process Transport Mitochondrion Degradation Negative Regulation Of CAMP Metabolic Process Negative Regulation Of Nucleotide Metabolic Process Organelle Disassembly Synaptic Transmission, Glutamatergic Receptor Internalization Regulation Of Synaptic Vesicle Priming Regulation Of Protein Localization To Plasma Membrane Regulation Of Adenylate Cyclase Activity Regulation Of Vesicle-mediated Transport Regulation Of Cyclase Activity Regulation Of Insulin Secretion Synaptic Vesicle Fusion To Presynaptic Membrane Cytoplasmic Transport Regulation Of Cellular Localization G-protein Coupled Receptor Internalization Regulation Of Peptide Hormone Secretion Cellular Component Assembly Positive Regulation Of Peptide Hormone Secretion Positive Regulation Of Peptide Secretion Receptor Metabolic Process Vesicle Docking Post-Golgi Vesicle-mediated Transport Regulation Of CAMP Biosynthetic Process Membrane Docking Regulation Of Protein Localization Desensitization Of G-protein Coupled Receptor Protein Signaling Pathway	Endomembrane System Organization Vesicle-mediated Transport Golgi Vesicle Docking Membrane Fusion Activation Of JAK2 Kinase Activity Creatinine Metabolic Process Isoleucine Metabolic Process Golgi Ribbon Formation Allantoin Metabolic Process Taurine Metabolic Process Activation Of Janus Kinase Activity Angiotensin-activated Signaling Pathway Endoplasmic Reticulum Tubular Network Organization Golgi Vesicle Transport Valine Metabolic Process Creatine Metabolic Process Response To Cycloheximide Succinate Metabolic Process 2-oxoglutarate Metabolic Process Oxaloacetate Metabolic Process Positive Regulation Of Receptor Recycling Positive Regulation Of Tyrosine Phosphorylation Of Stat5 Protein Plasma Membrane Fusion Insulin-like Growth Factor Receptor Signaling Pathway
Tagcloud ?		acetate alkylating amount apical associate attachment bound caco cellubrevin coimmunoprecipitation colocalizes connection define docking epithelium ethylmaleimide munc myristate phorbol predominantly quantity sec1 snap snare snares syntaxin thought verified vesicles	autophosphorylation called coimmunopricipitated couple da ecs fundamental indentified jak jak1 janus kinases lastly meg2 mutant nonreceptor phosphatases preferentially ptps searched substrate substrates trapping tyk2 tyr1175 tyrosine vegf vegfr2
Tagcloud (Difference) ?		acetate alkylating amount apical associate attachment bound caco cellubrevin coimmunoprecipitation colocalizes connection define docking epithelium ethylmaleimide munc myristate phorbol predominantly quantity sec1 snap snare snares syntaxin thought verified vesicles	autophosphorylation called coimmunopricipitated couple da ecs fundamental indentified jak jak1 janus kinases lastly meg2 mutant nonreceptor phosphatases preferentially ptps searched substrate substrates trapping tyk2 tyr1175 tyrosine vegf vegfr2
Tagcloud (Intersection) ?