NRAP and ACTN3

Number of citations of the paper that reports this interaction (PMID 12692149)
12

Data Source:
HPRD (two hybrid, in vitro)

		NRAP	ACTN3
Gene Name		nebulin-related anchoring protein	actinin, alpha 3 (gene/pseudogene)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Fascia Adherens Muscle Tendon Junction	Cytosol Actin Filament Focal Adhesion Pseudopodium Extracellular Vesicular Exosome
	Molecular Function	Actin Binding Zinc Ion Binding Muscle Alpha-actinin Binding	Actin Binding Integrin Binding Calcium Ion Binding Protein Binding Structural Constituent Of Muscle Protein Homodimerization Activity
	Biological Process	Biological_process	Muscle Filament Sliding Regulation Of Apoptotic Process Focal Adhesion Assembly
Pathways			Striated Muscle Contraction Nephrin interactions
Drugs
Diseases
GWAS			Bipolar disorder ( 21926972)
Protein-Protein Interactions		8 interactors: ACTA1 ACTB ACTN3 KLHL41 PRKAA2 TLN1 TRIM63 VCL	17 interactors: ABI3 ACTN1 ACTN2 ACTN4 ADORA2A BRCA1 C1orf94 KCTD6 MYPN NEBL NRAP PLEKHG2 REL RNF111 SUMO1P1 TRAF1 TRAF2
Entrez ID		4892	89
HPRD ID		04189	02148
Ensembl ID		ENSG00000197893	ENSG00000248746
Uniprot IDs		Q86VF7	B4DZQ2 Q08043 Q4VAM3
PDB IDs			1TJT 1WKU 3LUE
Enriched GO Terms of Interacting Partners?		Muscle Contraction Muscle System Process Platelet Aggregation Cell Junction Assembly Cell-cell Junction Organization Adherens Junction Organization Skeletal Muscle Adaptation Cellular Component Assembly Platelet Activation Actin Filament-based Process Movement Of Cell Or Subcellular Component Actin-myosin Filament Sliding Muscle Filament Sliding Actin-mediated Cell Contraction Adherens Junction Assembly Cell Development Cell-substrate Junction Assembly Homotypic Cell-cell Adhesion Actin Filament-based Movement Platelet Degranulation Blood Coagulation Myofibril Assembly Hemostasis Regulation Of Lateral Pseudopodium Assembly Cell Adhesion Anatomical Structure Morphogenesis Axonogenesis Single Organismal Cell-cell Adhesion Actomyosin Structure Organization Skeletal Muscle Fiber Adaptation Cell-cell Junction Assembly Axon Development Regulation Of Body Fluid Levels Cell Morphogenesis Involved In Neuron Differentiation Wound Healing Actin Cytoskeleton Organization Skeletal Muscle Tissue Development Neuron Projection Morphogenesis Cell Growth Skeletal Muscle Organ Development Cell Activation Striated Muscle Cell Development Response To Wounding Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Cell Morphogenesis Involved In Differentiation Cell-matrix Adhesion Muscle Cell Development Organelle Organization Response To External Stimulus Skeletal Muscle Atrophy	Protein Localization To Tight Junction Regulation Of Cell Death Cellular Component Assembly Protein Localization To Cell Junction Platelet Degranulation Regulation Of Apoptotic Process Actin Filament-based Process Actin Crosslink Formation Blood Coagulation Hemostasis Protein Polyubiquitination Focal Adhesion Assembly Platelet Activation Apoptotic Process Cell Junction Assembly Regulation Of Extrinsic Apoptotic Signaling Pathway NIK/NF-kappaB Signaling Cell-cell Junction Organization Programmed Cell Death Protein Autoubiquitination Cell Death Death Regulation Of Body Fluid Levels Tight Junction Assembly Adherens Junction Assembly Actin Cytoskeleton Organization Wound Healing Cytoskeleton Organization Positive Regulation Of Ion Transmembrane Transporter Activity Cell-substrate Junction Assembly Protein Homooligomerization Positive Regulation Of Transporter Activity I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Histone H4-K20 Methylation Positive Regulation Of Histone H4-K16 Acetylation Cardiac Muscle Thin Filament Assembly Actin Filament Bundle Assembly Response To Wounding Regulation Of Signal Transduction Actin Filament Organization Apical Junction Assembly Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Ion Transmembrane Transport Myofibril Assembly Exocytosis Positive Regulation Of Histone H3-K9 Acetylation Positive Regulation Of Cytokine Production Adherens Junction Organization Regulation Of Signaling Cellular Response To Tumor Necrosis Factor
Tagcloud ?			ace bdkrb2 chi2 cl cmj competition counter discriminate distributions elite explosive forward genotypic italian italians jump leg look players sedentary sj soccer squat stepwise strength top traits variance
Tagcloud (Difference) ?			ace bdkrb2 chi2 cl cmj competition counter discriminate distributions elite explosive forward genotypic italian italians jump leg look players sedentary sj soccer squat stepwise strength top traits variance
Tagcloud (Intersection) ?