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NOTCH3 and WDR25
Number of citations of the paper that reports this interaction (PMID
25356737
)
0
Data Source:
BioGRID
(pull down)
NOTCH3
WDR25
Gene Name
notch 3
WD repeat domain 25
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Golgi Membrane
Extracellular Region
Nucleoplasm
Cytoplasm
Endoplasmic Reticulum Membrane
Cytosol
Plasma Membrane
Actin Cytoskeleton
Integral Component Of Membrane
Receptor Complex
Molecular Function
Calcium Ion Binding
Protein Binding
Enzyme Binding
Biological Process
Regulation Of Transcription, DNA-templated
Transcription Initiation From RNA Polymerase II Promoter
Notch Signaling Pathway
Notch Receptor Processing
Gene Expression
Forebrain Development
Negative Regulation Of Neuron Differentiation
Positive Regulation Of Smooth Muscle Cell Proliferation
Neuron Fate Commitment
Glomerular Capillary Formation
Pathways
Notch-HLH transcription pathway
Generic Transcription Pathway
Pre-NOTCH Processing in Golgi
Pre-NOTCH Transcription and Translation
Signaling by NOTCH
Pre-NOTCH Processing in the Endoplasmic Reticulum
Pre-NOTCH Expression and Processing
Signaling by NOTCH3
Drugs
Diseases
GWAS
Protein-Protein Interactions
40 interactors:
BAG2
BTF3L4
C1QL1
C8orf76
CBFA2T2
CHUK
CNTD1
CPNE6
CRIP2
CSNK2B
DLL1
EGFL7
FBLN1
GGT6
JAG1
JAG2
KAT2B
MAML1
MAML2
MAML3
MPPED2
MYC
NEDD9
PPIA
PSEN1
PSEN2
RBPJ
RET
RMI2
SCGB3A1
SLC39A1
SNW1
SNX19
SORBS3
SPTLC2
TMEM108
TNNT2
TPT1
WDR25
XKR8
7 interactors:
KRT31
KRT40
NOTCH2NL
NOTCH3
PNMA1
PSME3
TRIM23
Entrez ID
4854
79446
HPRD ID
02607
14649
Ensembl ID
ENSG00000074181
ENSG00000176473
Uniprot IDs
Q9UM47
G3V2K8
Q64LD2
PDB IDs
Enriched GO Terms of Interacting Partners
?
Notch Signaling Pathway
Notch Receptor Processing
Transcription Initiation From RNA Polymerase II Promoter
Tissue Morphogenesis
DNA-templated Transcription, Initiation
Morphogenesis Of An Epithelium
Tissue Development
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Cellular Metabolic Process
Positive Regulation Of Transcription, DNA-templated
Epithelium Development
Positive Regulation Of Metabolic Process
Immune System Development
Positive Regulation Of Macromolecule Biosynthetic Process
Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Gene Expression
System Development
Positive Regulation Of Cellular Biosynthetic Process
Multicellular Organismal Development
Hemopoiesis
Cell Surface Receptor Signaling Pathway
Anatomical Structure Development
Cell Fate Commitment
Developmental Process
Tube Development
Positive Regulation Of Signal Transduction
Cell Differentiation
Regulation Of Cell Differentiation
Organ Morphogenesis
Auditory Receptor Cell Differentiation
Heart Morphogenesis
Epithelial Tube Morphogenesis
Membrane Protein Proteolysis
Myeloid Leukocyte Differentiation
Positive Regulation Of Transcription Of Notch Receptor Target
Hair Cell Differentiation
Auditory Receptor Cell Fate Commitment
Stem Cell Development
Tube Morphogenesis
Myoblast Differentiation
Cell Development
Endothelial Tube Morphogenesis
Generation Of Neurons
Notch Signaling Involved In Heart Development
Amyloid Precursor Protein Catabolic Process
Nervous System Development
Stem Cell Maintenance
Negative Regulation Of Cell Differentiation
Stem Cell Differentiation
Inner Ear Receptor Cell Differentiation
Tagcloud
?
barrett
cdx1
columnar
dnmaml
esophagus
formerly
goblet
hes1
jag1
k13
k14
k18
k19
k20
k5
k8
keratins
klf4
mastermind
metaplasia
muc17
muc2
muc3b
muc5b
mucins
organotypic
transdifferentiation
Tagcloud (Difference)
?
barrett
cdx1
columnar
dnmaml
esophagus
formerly
goblet
hes1
jag1
k13
k14
k18
k19
k20
k5
k8
keratins
klf4
mastermind
metaplasia
muc17
muc2
muc3b
muc5b
mucins
organotypic
transdifferentiation
Tagcloud (Intersection)
?