NEUROG1 and TARBP2

Number of citations of the paper that reports this interaction (PMID 20211142)
148

Data Source:
BioGRID (two hybrid)

		NEUROG1	TARBP2
Gene Name		neurogenin 1	TAR (HIV-1) RNA binding protein 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Perikaryon	Nucleus Nucleoplasm Cytoplasm Cytosol RISC Complex Micro-ribonucleoprotein Complex Perinuclear Region Of Cytoplasm
	Molecular Function	Transcription Factor Binding Transcription Factor Activity DNA Binding Chromatin Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Dimerization Activity E-box Binding	Double-stranded RNA Binding Protein Binding SiRNA Binding MiRNA Binding Protein Homodimerization Activity
	Biological Process	Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Nervous System Development Neuron Differentiation Positive Regulation Of Exit From Mitosis Inner Ear Morphogenesis Cell Fate Commitment Positive Regulation Of Neuron Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity	Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Translation Negative Regulation Of Protein Kinase Activity Gene Expression Production Of SiRNA Involved In RNA Interference Targeting Of MRNA For Destruction Involved In RNA Interference Pre-miRNA Processing MiRNA Loading Onto RISC Involved In Gene Silencing By MiRNA Positive Regulation Of Viral Genome Replication Regulation Of Viral Transcription Negative Regulation Of Defense Response To Virus By Host
Pathways			Regulatory RNA pathways MicroRNA (miRNA) biogenesis Small interfering RNA (siRNA) biogenesis
Drugs
Diseases
GWAS
Protein-Protein Interactions		6 interactors: CBFA2T2 CREBBP RUNX1T1 SMAD1 TARBP2 TCF4	21 interactors: AGO2 APP DICER1 EIF2AK2 HDHD2 IKBKG KCNIP3 MED21 NEDD4L NEUROG1 NF2 NUDT18 PRKRA RBM14 STRBP TCEANC TGIF2 TOP1 TRAF4 VAV2 ZNF346
Entrez ID		4762	6895
HPRD ID		03430	05446
Ensembl ID		ENSG00000181965	ENSG00000139546
Uniprot IDs		F1T0H3 Q92886	Q15633
PDB IDs			2CPN 3ADL 3LLH
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Gene Expression Production Of MiRNAs Involved In Gene Silencing By MiRNA Regulation Of Transcription From RNA Polymerase II Promoter Gene Silencing By MiRNA Cellular Response To DsRNA Posttranscriptional Gene Silencing Negative Regulation Of Cellular Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Positive Regulation Of Neuron Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Gene Silencing By RNA Positive Regulation Of Neurogenesis Response To DsRNA Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Biosynthetic Process Positive Regulation Of Cell Development Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Neuron Differentiation Positive Regulation Of Gene Expression RNA Metabolic Process Gene Silencing Regulation Of Cell Differentiation Positive Regulation Of Cellular Biosynthetic Process Cell Differentiation Cellular Macromolecular Complex Assembly Gene Expression Embryonic Morphogenesis Fat Cell Differentiation Regulation Of Neurogenesis MiRNA Loading Onto RISC Involved In Gene Silencing By MiRNA Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition Catenin Import Into Nucleus Cellular Component Assembly Negative Regulation Of Cell Differentiation Stem Cell Maintenance Transcription Initiation From RNA Polymerase II Promoter Positive Regulation Of Cell Morphogenesis Involved In Differentiation Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Targeting Of MRNA For Destruction Involved In RNA Interference N-terminal Peptidyl-lysine Acetylation Regulation Of Cell Development Positive Regulation Of Cell Differentiation	Regulation Of Gene Expression RNA Interference Nucleobase-containing Compound Metabolic Process RNA Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Gene Expression Cellular Nitrogen Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of NIK/NF-kappaB Signaling Posttranscriptional Regulation Of Gene Expression Regulation Of NIK/NF-kappaB Signaling Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Cellular Response To DsRNA Posttranscriptional Gene Silencing Positive Regulation Of Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Programmed Cell Death Regulation Of Apoptotic Process Cell Death Death Gene Silencing By RNA Positive Regulation Of Cellular Metabolic Process Regulation Of Cell Death Response To DsRNA Production Of SiRNA Involved In RNA Interference Regulation Of Kinase Activity Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Response To Virus Cellular Macromolecule Biosynthetic Process Regulation Of RNA Biosynthetic Process Pre-miRNA Processing Macromolecule Biosynthetic Process Negative Regulation Of Gene Expression Regulation Of RNA Metabolic Process Negative Regulation Of Biosynthetic Process Gene Silencing Sensory Organ Development Apoptotic Process Activation Of NF-kappaB-inducing Kinase Activity Production Of MiRNAs Involved In Gene Silencing By MiRNA Multicellular Organismal Development Positive Regulation Of Gene Expression Negative Regulation Of Cellular Metabolic Process Regulation Of Cell Differentiation Response To Stress
Tagcloud ?		appearance comprehending correlate epigenetic epigenetics etc foxg1 grik3 hand2 hox integrating islands luad methylated nkx6 pik3ca pik3r3 pou4f2 prkcb ptgdr raf1 rap1a refers stages subnetwork tlx3 ubc ultimate wise	computational conducting defining deregulated destabilization destabilizes destabilizing displaying elements govern governed huntington integrating isogenic metastatic modulators overrepresented represses searches srse srses tbses termed transcriptionally transcripts unbiased uncovered unexplored znf395
Tagcloud (Difference) ?		appearance comprehending correlate epigenetic epigenetics etc foxg1 grik3 hand2 hox islands luad methylated nkx6 pik3ca pik3r3 pou4f2 prkcb ptgdr raf1 rap1a refers stages subnetwork tlx3 ubc ultimate wise	computational conducting defining deregulated destabilization destabilizes destabilizing displaying elements govern governed huntington isogenic metastatic modulators overrepresented represses searches srse srses tbses termed transcriptionally transcripts unbiased uncovered unexplored znf395
Tagcloud (Intersection) ?		integrating