NDUFA7 and ELAC2

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		NDUFA7	ELAC2
Gene Name		NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa	elaC ribonuclease Z 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrial Inner Membrane Mitochondrial Respiratory Chain Complex I	Nucleus Nucleoplasm Mitochondrion
	Molecular Function	NADH Dehydrogenase (ubiquinone) Activity	Endonuclease Activity Poly(A) RNA Binding Metal Ion Binding
	Biological Process	Mitochondrial Electron Transport, NADH To Ubiquinone Respiratory Electron Transport Chain Cellular Metabolic Process Small Molecule Metabolic Process	Mitochondrial TRNA 3'-trailer Cleavage, Endonucleolytic
Pathways		Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. Respiratory electron transport The citric acid (TCA) cycle and respiratory electron transport
Drugs		NADH
Diseases
GWAS
Protein-Protein Interactions		5 interactors: ELAC2 MDFI PRKAB1 STARD9 UPF2	8 interactors: ASCC2 CTBP1 CTBP2 CUX1 GOLM1 NDUFA7 RING1 SMAD2
Entrez ID		4701	60528
HPRD ID		11885	05641
Ensembl ID		ENSG00000267855	ENSG00000006744
Uniprot IDs		O95182	G5E9D5 Q9BQ52
PDB IDs
Enriched GO Terms of Interacting Partners?		Mitochondrial TRNA 3'-trailer Cleavage, Endonucleolytic TRNA 3'-trailer Cleavage Mitochondrial RNA 3'-end Processing TRNA 3'-end Processing	Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process White Fat Cell Differentiation Transcription, DNA-templated RNA Biosynthetic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Viral Genome Replication Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process RNA Metabolic Process Gene Expression Nitrogen Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter By Histone Modification Positive Regulation Of Nodal Signaling Pathway Involved In Determination Of Lateral Mesoderm Left/right Asymmetry Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Fat Cell Differentiation Regulation Of RNA Metabolic Process Regulation Of Nodal Signaling Pathway Involved In Determination Of Lateral Mesoderm Left/right Asymmetry Zygotic Specification Of Dorsal/ventral Axis Negative Regulation Of Cell Proliferation Positive Regulation Of Cell Morphogenesis Involved In Differentiation Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Retinoic Acid Receptor Signaling Pathway Negative Regulation Of Transcription From RNA Polymerase II Promoter Viral Life Cycle Regulation Of Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Mesoderm Development Primary MiRNA Processing Positive Regulation Of Chromatin Binding Regulation Of Nodal Signaling Pathway Common-partner SMAD Protein Phosphorylation Transcription From RNA Polymerase II Promoter Positive Regulation Of Activin Receptor Signaling Pathway Lung Development Anterior/posterior Pattern Specification Respiratory Tube Development Negative Regulation Of Histone H4 Acetylation Regulation Of Binding
Tagcloud ?			abundant biogenesis cointroducing constitute created discover discovered endonuclease g2 ligation mature micrornas mirnas northern oligoribonucleotide precise progressively retained rnas sequenced splinted tga throughput tightly trf trfs trna trnas ultra
Tagcloud (Difference) ?			abundant biogenesis cointroducing constitute created discover discovered endonuclease g2 ligation mature micrornas mirnas northern oligoribonucleotide precise progressively retained rnas sequenced splinted tga throughput tightly trf trfs trna trnas ultra
Tagcloud (Intersection) ?