MYH2 and DGKD

Number of citations of the paper that reports this interaction (PMID 10082674)
6

Data Source:
HPRD (in vitro)

		MYH2	DGKD
Gene Name		myosin, heavy chain 2, skeletal muscle, adult	diacylglycerol kinase, delta 130kDa
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Apparatus Actomyosin Contractile Ring Cytosol Muscle Myosin Complex Cell-cell Junction Myofibril Sarcomere A Band Myosin Filament Protein Complex	Cytoplasm Plasma Membrane Cytoplasmic Membrane-bounded Vesicle
	Molecular Function	Microfilament Motor Activity Actin Binding Protein Binding Calmodulin Binding ATP Binding	NAD+ Kinase Activity Diacylglycerol Kinase Activity Protein Binding ATP Binding Diacylglycerol Binding Protein Homodimerization Activity Metal Ion Binding Protein Heterodimerization Activity
	Biological Process	Plasma Membrane Repair Muscle Contraction Metabolic Process Response To Activity Muscle Filament Sliding Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Innate Immune Response Membrane Organization	Endocytosis Signal Transduction Epidermal Growth Factor Receptor Signaling Pathway Protein Kinase C-activating G-protein Coupled Receptor Signaling Pathway Multicellular Organismal Development Blood Coagulation Response To Organic Substance Protein Transport Cell Growth Phosphorylation Second-messenger-mediated Signaling Platelet Activation Diacylglycerol Metabolic Process Protein Homooligomerization
Pathways		Translocation of GLUT4 to the plasma membrane Fcgamma receptor (FCGR) dependent phagocytosis Regulation of actin dynamics for phagocytic cup formation Innate Immune System	G alpha (q) signalling events G alpha (q) signalling events Signaling by GPCR GPCR downstream signaling Gastrin-CREB signalling pathway via PKC and MAPK Platelet activation, signaling and aggregation Effects of PIP2 hydrolysis
Drugs
Diseases
GWAS			Bilirubin levels ( 20639394) Calcium levels ( 20705733) Crohn's disease ( 22412388)
Protein-Protein Interactions		6 interactors: AMPD1 DGKD OBSCN PRKCE PTK2B S100A4	7 interactors: DGKH HAX1 IGSF21 MYH2 PRKCA SREK1 TNFRSF14
Entrez ID		4620	8527
HPRD ID		01173	03492
Ensembl ID		ENSG00000125414	ENSG00000077044
Uniprot IDs		Q567P6 Q9UKX2	Q16760
PDB IDs			1R79 3BQ7
Enriched GO Terms of Interacting Partners?		Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Response To Organic Substance Phosphate-containing Compound Metabolic Process Positive Regulation Of Epithelial Cell Migration Response To Ammonium Ion Negative Regulation Of Ion Transport Positive Regulation Of Cellular Glucuronidation Positive Regulation Of Actin Filament Polymerization Positive Regulation Of Synaptic Transmission Actomyosin Structure Organization Regulation Of Receptor Activity Positive Regulation Of Cell-substrate Adhesion Positive Regulation Of Protein Polymerization Regulation Of Intracellular Signal Transduction Cell Activation Regulation Of CGMP-mediated Signaling Marginal Zone B Cell Differentiation Positive Regulation Of B Cell Chemotaxis TRAM-dependent Toll-like Receptor 4 Signaling Pathway Phosphorylation Response To Ethanol Intracellular Signal Transduction Regulation Of Ion Transmembrane Transporter Activity Regulation Of Epithelial Cell Migration Response To Alkaloid Regulation Of Transmembrane Transporter Activity Regulation Of Carbohydrate Metabolic Process Leukocyte Activation Involved In Immune Response Positive Regulation Of Cytosolic Calcium Ion Concentration Regulation Of Ion Homeostasis Positive Regulation Of Intracellular Signal Transduction Protein Localization To M-band Positive Regulation Of Protein Complex Assembly Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Regulation Of Actin Filament Polymerization Cytosolic Calcium Ion Homeostasis Activation Of Janus Kinase Activity Platelet Activation Regulation Of Cell-substrate Adhesion Positive Regulation Of Cytoskeleton Organization Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Regulation Of Peptidyl-tyrosine Phosphorylation Neurotrophin TRK Receptor Signaling Pathway Apoptotic Process Neurotrophin Signaling Pathway Regulation Of I-kappaB Kinase/NF-kappaB Signaling	Regulation Of Peptidyl-tyrosine Phosphorylation Positive Regulation Of Immune System Process Positive Regulation Of Myeloid Leukocyte Differentiation Regulation Of Cellular Amino Acid Metabolic Process Regulation Of Immune System Process Positive Regulation Of Myeloid Cell Differentiation Regulation Of Cellular Ketone Metabolic Process Positive Regulation Of Dense Core Granule Biogenesis Wound Healing Regulation Of Myeloid Leukocyte Differentiation Regulation Of Protein Transport Regulation Of Establishment Of Protein Localization Response To Wounding Histone H3-T6 Phosphorylation Response To Cytokine Positive Regulation Of Protein Phosphorylation Positive Regulation Of Peptidyl-tyrosine Phosphorylation Regulation Of Protein Localization Regulation Of Myeloid Cell Differentiation Positive Regulation Of Phosphorylation Regulation Of Protein Targeting To Mitochondrion Positive Regulation Of Cytokine Secretion Involved In Immune Response Platelet Activation Positive Regulation Of Protein Modification Process Regulation Of Cellular Localization Regulation Of Protein Phosphorylation Peptidyl-serine Autophosphorylation Positive Regulation Of Lipopolysaccharide-mediated Signaling Pathway Negative Regulation Of Alpha-beta T Cell Proliferation Plasma Membrane Repair Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Granulocyte Differentiation Desmosome Assembly Negative Regulation Of Glial Cell Apoptotic Process Positive Regulation Of Protein Metabolic Process Regulation Of Mitochondrion Degradation Negative Regulation Of Glucose Import Positive Regulation Of Cell Migration Immune Response Positive Regulation Of Cell Motility Regulation Of Phosphorylation Positive Regulation Of Macrophage Differentiation Regulation Of Cytokine Secretion Involved In Immune Response Positive Regulation Of Cellular Component Movement Defense Response Desmosome Organization Positive Regulation Of Locomotion Regulation Of Cell-cell Adhesion Positive Regulation Of Cell Adhesion Cell Surface Receptor Signaling Pathway
Tagcloud ?		breakpoint breaks coliai cryb1 d17s1 d17s19 d17s6 d17z erba1 gaa galk gcsf ghc hox2 hybrids isoenzymes mpo myh1 ngfr ngl probes pter qter regionally rnp2 rnu2 tk1 transfectant um
Tagcloud (Difference) ?		breakpoint breaks coliai cryb1 d17s1 d17s19 d17s6 d17z erba1 gaa galk gcsf ghc hox2 hybrids isoenzymes mpo myh1 ngfr ngl probes pter qter regionally rnp2 rnu2 tk1 transfectant um
Tagcloud (Intersection) ?