MVD and BTAF1

Number of citations of the paper that reports this interaction (PMID 12646231)
9

Data Source:
HPRD (in vivo, two hybrid)

		MVD	BTAF1
Gene Name		mevalonate (diphospho) decarboxylase	BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Peroxisome Cytosol	Nucleus
	Molecular Function	Diphosphomevalonate Decarboxylase Activity ATP Binding Hsp70 Protein Binding Protein Homodimerization Activity	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Helicase Activity ATP Binding
	Biological Process	Dolichol-linked Oligosaccharide Biosynthetic Process Dolichyl Diphosphate Biosynthetic Process Cholesterol Biosynthetic Process Positive Regulation Of Cell Proliferation Isoprenoid Biosynthetic Process Protein N-linked Glycosylation Via Asparagine Isopentenyl Diphosphate Biosynthetic Process, Mevalonate Pathway Post-translational Protein Modification Cellular Protein Metabolic Process Small Molecule Metabolic Process	Metabolic Process Negative Regulation Of Chromatin Binding Negative Regulation Of Transcription, DNA-templated
Pathways		Diseases of glycosylation Metabolism of lipids and lipoproteins Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS) Defective MGAT2 causes MGAT2-CDG (CDG-2a) Defective ALG1 causes ALG1-CDG (CDG-1k) Defective MOGS causes MOGS-CDG (CDG-2b) Regulation of cholesterol biosynthesis by SREBP (SREBF) Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein Defective ALG9 causes ALG9-CDG (CDG-1l) Defective MAN1B1 causes MRT15 Synthesis of Dolichyl-phosphate Defective ALG11 causes ALG11-CDG (CDG-1p) Defective ALG2 causes ALG2-CDG (CDG-1i) Cholesterol biosynthesis Defective ALG3 causes ALG3-CDG (CDG-1d) Post-translational protein modification Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2 Synthesis of substrates in N-glycan biosythesis Defective B4GALT1 causes B4GALT1-CDG (CDG-2d) Defective RFT1 causes RFT1-CDG (CDG-1n) Defective ALG6 causes ALG6-CDG (CDG-1c) Asparagine N-linked glycosylation Defective ALG8 causes ALG8-CDG (CDG-1h) Defective MPDU1 causes MPDU1-CDG (CDG-1f) Defective ALG12 causes ALG12-CDG (CDG-1g) Activation of gene expression by SREBF (SREBP) Diseases associated with N-glycosylation of proteins
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: BTAF1 EEF1G EIF4EBP1 GNB5 HSPA9	4 interactors: MVD PIAS4 PIH1D3 TBP
Entrez ID		4597	9044
HPRD ID		04454	05546
Ensembl ID		ENSG00000167508	ENSG00000095564
Uniprot IDs		P53602	O14981 Q2M1V9 Q8N6J1
PDB IDs		3D4J
Enriched GO Terms of Interacting Partners?			Positive Regulation Of Keratinocyte Apoptotic Process Isopentenyl Diphosphate Biosynthetic Process, Mevalonate Pathway Isopentenyl Diphosphate Metabolic Process Dolichyl Diphosphate Biosynthetic Process Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Positive Regulation Of Protein Sumoylation Axonemal Dynein Complex Assembly Chromatin Silencing At RDNA
Tagcloud ?		aggressive analyse bcc behavior carcinomas exceeded explain fact immunohistochemically indicator ka keratoacanthomas metastatic microvessel neoplasms nod nodular paraffin perilesional psmvd scc scl sclerosing sections slow stained tmvd vascularized viii
Tagcloud (Difference) ?		aggressive analyse bcc behavior carcinomas exceeded explain fact immunohistochemically indicator ka keratoacanthomas metastatic microvessel neoplasms nod nodular paraffin perilesional psmvd scc scl sclerosing sections slow stained tmvd vascularized viii
Tagcloud (Intersection) ?