ARSE and COQ6

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ARSE	COQ6
Gene Name		arylsulfatase E (chondrodysplasia punctata 1)	coenzyme Q6 monooxygenase
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Lumen Golgi Stack Extracellular Vesicular Exosome	Mitochondrion Golgi Apparatus Cell Projection
	Molecular Function	Arylsulfatase Activity Metal Ion Binding	Monooxygenase Activity Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen, NAD(P)H As One Donor, And Incorporation Of One Atom Of Oxygen Flavin Adenine Dinucleotide Binding
	Biological Process	Skeletal System Development Sphingolipid Metabolic Process Glycosphingolipid Metabolic Process Post-translational Protein Modification Cellular Protein Metabolic Process Small Molecule Metabolic Process	Ubiquinone Biosynthetic Process Small Molecule Metabolic Process Secondary Metabolite Biosynthetic Process Oxidation-reduction Process
Pathways		Sphingolipid metabolism Metabolism of lipids and lipoproteins Glycosphingolipid metabolism Post-translational protein modification The activation of arylsulfatases Gamma carboxylation, hypusine formation and arylsulfatase activation	Metabolism of lipids and lipoproteins Ubiquinol biosynthesis
Drugs
Diseases
GWAS		Height ( 21998595 22021425)
Protein-Protein Interactions		4 interactors: COQ6 NDN TMEM259 TNK2	3 interactors: APP ARSE ZBTB16
Entrez ID		415	51004
HPRD ID		02171	16742
Ensembl ID		ENSG00000157399	ENSG00000119723
Uniprot IDs		F5GYY5 F5H324 P51690	B7Z357 Q9Y2Z9
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Clathrin-mediated Endocytosis Respiratory System Process Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Ubiquinone Biosynthetic Process Secondary Metabolite Biosynthetic Process Ubiquinone Metabolic Process Axonal Fasciculation Cell Migration Enzyme Linked Receptor Protein Signaling Pathway Cell Motility Genetic Imprinting Neuron Recognition Quinone Metabolic Process Peptidyl-tyrosine Autophosphorylation	Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Collateral Sprouting Axon Midline Choice Point Recognition Positive Regulation Of NK T Cell Differentiation Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Male Germ-line Stem Cell Asymmetric Division Axon Choice Point Recognition Neuron Remodeling Skeletal System Development Cellular Copper Ion Homeostasis Cellular Protein Modification Process Copper Ion Homeostasis Suckling Behavior Negative Regulation Of Cell Differentiation Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Sexual Reproduction Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Positive Regulation Of Chondrocyte Differentiation Mating Behavior Endoplasmic Reticulum Calcium Ion Homeostasis RNA Polyadenylation Neuron Recognition Apoptotic Process Central Nervous System Development Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Programmed Cell Death Stem Cell Division Positive Regulation Of Alpha-beta T Cell Differentiation Positive Regulation Of Cartilage Development System Development Reproduction Ionotropic Glutamate Receptor Signaling Pathway Regulation Of G2/M Transition Of Mitotic Cell Cycle Cell Death Death Regulation Of Cell Cycle G2/M Phase Transition Embryonic Hindlimb Morphogenesis Cellular Protein Metabolic Process Axon Cargo Transport Mating Neuromuscular Junction Development Forelimb Morphogenesis Positive Regulation Of Fat Cell Differentiation Positive Regulation Of Mitotic Cell Cycle Phase Transition Neuron Apoptotic Process Positive Regulation Of Cell Cycle Phase Transition Hindlimb Morphogenesis
Tagcloud ?			11p12 14q24 6q12 9p24 abcd4 acyp1 amplifications apip cd109 cd274 commd9 cttn fjx1 hbld1 interscience jdp2 jpages ltbp2 myo6 otscc pdhx pinpointed ppfia1 q14 rln1 slc1a1 suppmat trim44 znf410
Tagcloud (Difference) ?			11p12 14q24 6q12 9p24 abcd4 acyp1 amplifications apip cd109 cd274 commd9 cttn fjx1 hbld1 interscience jdp2 jpages ltbp2 myo6 otscc pdhx pinpointed ppfia1 q14 rln1 slc1a1 suppmat trim44 znf410
Tagcloud (Intersection) ?