KRT6A and DSP

Number of citations of the paper that reports this interaction (PMID 7525601)
43

Data Source:
HPRD (in vitro)

		KRT6A	DSP
Gene Name		keratin 6A, type II	desmoplakin
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Membrane Keratin Filament Extracellular Vesicular Exosome	Cornified Envelope Nucleus Mitochondrion Intermediate Filament Plasma Membrane Fascia Adherens Intercalated Disc Basolateral Plasma Membrane Desmosome Extracellular Vesicular Exosome
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding	Protein Kinase C Binding Structural Molecule Activity Structural Constituent Of Cytoskeleton Protein Binding Protein Binding, Bridging Poly(A) RNA Binding Cell Adhesion Molecule Binding Scaffold Protein Binding
	Biological Process	Morphogenesis Of An Epithelium Positive Regulation Of Cell Proliferation Cell Differentiation Wound Healing	Desmosome Organization Ventricular Compact Myocardium Morphogenesis Apoptotic Process Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Epidermis Development Single Organismal Cell-cell Adhesion Peptide Cross-linking Keratinocyte Differentiation Adherens Junction Organization Wound Healing Intermediate Filament Organization Protein Localization To Adherens Junction Ventricular Cardiac Muscle Cell Action Potential Bundle Of His Cell To Purkinje Myocyte Communication Regulation Of Heart Rate By Cardiac Conduction
Pathways			Apoptotic cleavage of cell adhesion proteins Apoptotic cleavage of cellular proteins Programmed Cell Death Apoptotic execution phase
Drugs
Diseases
GWAS			Interstitial lung disease ( 23583980)
Protein-Protein Interactions		18 interactors: CCDC53 CCDC85B DSP GOLGA2 HGS KDM1A KIFC3 KRT13 KRT15 KRT17 KRT31 KRT38 KRT40 SGTA TCHP TFIP11 TRIM23 TRIM54	28 interactors: ARID3A CASP10 CASP2 CASP4 CASP6 CASP7 CASP9 CDH5 COL17A1 CSTA DES DSC1 EVPL IVL JUP KRT1 KRT5 KRT6A PECAM1 PKP1 PKP2 PKP3 PKP4 PRKACA PRKCE PSEN1 UCHL5 VIM
Entrez ID		3853	1832
HPRD ID		01011	00513
Ensembl ID		ENSG00000205420	ENSG00000096696
Uniprot IDs		P02538	D7RX09 P15924
PDB IDs			1LM5 1LM7 3R6N
Enriched GO Terms of Interacting Partners?		Epidermis Development Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Negative Regulation Of Protein Binding Spliceosomal Complex Disassembly Regulation Of Primitive Erythrocyte Differentiation	Desmosome Assembly Cell Junction Assembly Desmosome Organization Cell Adhesion Execution Phase Of Apoptosis Apoptotic Process Programmed Cell Death Cell Death Death Epithelium Development Tissue Development Developmental Process Anatomical Structure Development Cell-cell Junction Organization Skin Development Cell-cell Junction Assembly Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Intermediate Filament Organization Single Organismal Cell-cell Adhesion Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Proteolysis Organ Development Epidermis Development Multicellular Organismal Development System Development Intermediate Filament Cytoskeleton Organization Intermediate Filament Bundle Assembly Intermediate Filament-based Process Cardiac Conduction Peptide Cross-linking Cellular Component Assembly Bundle Of His Cell To Purkinje Myocyte Communication Regulation Of Heart Contraction Apoptotic Signaling Pathway Regulation Of Tight Junction Assembly Intrinsic Apoptotic Signaling Pathway Regulation Of Endopeptidase Activity Cell Communication By Electrical Coupling Involved In Cardiac Conduction Regulation Of Peptidyl-tyrosine Phosphorylation Regulation Of Heart Rate Regulation Of Cardiac Muscle Contraction Regulation Of Peptidase Activity Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process By Cytochrome C Hemidesmosome Assembly Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Neurotrophin TRK Receptor Signaling Pathway Positive Regulation Of Cell Cycle Process Signaling Neurotrophin Signaling Pathway Cell Communication By Electrical Coupling
Tagcloud ?			aspirated cam5 cleaner dsus gcdfp ham56 hmb45 ipx k903 l26 mac387 mcea mcead14 nonneoplastic opd papanicolaou pcea plap processor scant scraped semiquantitatively slides thinprep tlp tlus tpp uchl unstained
Tagcloud (Difference) ?			aspirated cam5 cleaner dsus gcdfp ham56 hmb45 ipx k903 l26 mac387 mcea mcead14 nonneoplastic opd papanicolaou pcea plap processor scant scraped semiquantitatively slides thinprep tlp tlus tpp uchl unstained
Tagcloud (Intersection) ?