IPO5 and NUP62

Number of citations of the paper that reports this interaction (PMID 9114010)
35

Data Source:
HPRD (in vivo, in vitro)

		IPO5	NUP62
Gene Name		importin 5	nucleoporin 62kDa
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nuclear Pore Nucleoplasm Nucleolus Cytoplasm Golgi Apparatus Membrane Nuclear Membrane Intracellular Membrane-bounded Organelle	Spindle Pole Nuclear Envelope Nuclear Pore Cytoplasm Ribonucleoprotein Complex Nucleocytoplasmic Shuttling Complex Nuclear Membrane Intracellular Membrane-bounded Organelle Pore Complex
	Molecular Function	GTPase Inhibitor Activity Protein Binding Ran GTPase Binding Protein Transporter Activity Poly(A) RNA Binding	Chromatin Binding Nucleocytoplasmic Transporter Activity Protein Binding Structural Constituent Of Nuclear Pore Receptor Signaling Complex Scaffold Activity SH2 Domain Binding Ubiquitin Binding Thyroid Hormone Receptor Binding PTB Domain Binding
	Biological Process	NLS-bearing Protein Import Into Nucleus Ribosomal Protein Import Into Nucleus Viral Process Positive Regulation Of Protein Import Into Nucleus Negative Regulation Of Catalytic Activity Cellular Response To Amino Acid Stimulus	Mitotic Cell Cycle Carbohydrate Metabolic Process Transcription, DNA-templated Nucleocytoplasmic Transport Mitotic Nuclear Envelope Disassembly Cell Surface Receptor Signaling Pathway Cell Aging Cell Death Negative Regulation Of Cell Proliferation Hexose Transport Pathogenesis Hormone-mediated Signaling Pathway Regulation Of Signal Transduction Gene Expression Regulation Of Glucose Transport Protein Transport Glucose Transport Viral Process Viral Life Cycle Viral Transcription Cytokine-mediated Signaling Pathway Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of MAP Kinase Activity Small Molecule Metabolic Process Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Positive Regulation Of Transcription, DNA-templated Regulation Of Ras Protein Signal Transduction Negative Regulation Of Ras Protein Signal Transduction MRNA Transport Transmembrane Transport
Pathways		Influenza Viral RNA Transcription and Replication Influenza Infection Influenza Life Cycle vRNP Assembly	Mitotic Prophase HIV Infection Nuclear import of Rev protein Regulatory RNA pathways Rev-mediated nuclear export of HIV RNA Nuclear Envelope Breakdown SLC-mediated transmembrane transport M Phase Influenza Life Cycle HIV Life Cycle Influenza Viral RNA Transcription and Replication Rev-mediated nuclear export of HIV RNA Myoclonic epilepsy of Lafora Glycogen storage diseases Transcriptional regulation by small RNAs Vpr-mediated nuclear import of PICs ISG15 antiviral mechanism Interferon Signaling Host Interactions of HIV factors Nuclear Pore Complex (NPC) Disassembly Regulation of Glucokinase by Glucokinase Regulatory Protein Cytokine Signaling in Immune system Interactions of Vpr with host cellular proteins Interactions of Rev with host cellular proteins Influenza Infection Hexose transport Cell Cycle, Mitotic Late Phase of HIV Life Cycle Antiviral mechanism by IFN-stimulated genes Viral Messenger RNA Synthesis Metabolism of carbohydrates Glucose transport
Drugs
Diseases
GWAS
Protein-Protein Interactions		22 interactors: ACD BHLHB9 DPPA3 DTNBP1 H1F0 NUP153 NUP214 NUP62 NUP98 RAG2 RAN RANBP2 RPL13 RPL23 RPL23A RPL5 RPL7 RPS7 SRP19 TERF1 TINF2 WASL	65 interactors: ABI2 ADAM15 AGR3 ATXN7 BFSP1 BLOC1S6 C1orf216 CCDC121 CCDC146 CCDC150 CCDC153 CCDC53 CCHCR1 CENPU CEP57L1 CLIC1 CRCT1 DDX3X DGCR6 DTNB FABP3 GOPC GORASP2 GTF2E2 HAUS1 HSF2 IFT20 IK IKBIP IPO5 ISCU KANSL1 KIFC3 KLHL32 KPNA1 KPNA2 KPNB1 KRT20 LMO2 MUC1 MYO15B NFX1 NUP153 NUP54 NUP98 NUPL1 NUTF2 NXF1 NXF2 OGT OIP5 PBX2 PHF21A PIN1 PTMA RANBP2 SMARCE1 SNAPC5 SP1 SSC5D THAP1 TRAF3 TXLNA XPO1 XPO6
Entrez ID		3843	23636
HPRD ID		03597	05782
Ensembl ID		ENSG00000065150	ENSG00000213024
Uniprot IDs		B3KWG6 O00410 Q9BVS9	P37198
PDB IDs			2H4D
Enriched GO Terms of Interacting Partners?		Viral Transcription Viral Life Cycle Protein Localization To Organelle Membrane Organization Establishment Of Protein Localization To Organelle Cytoplasmic Transport Viral Process Protein Targeting Intracellular Transport Protein Localization Cellular Localization Establishment Of Localization In Cell Cellular Protein Localization Protein Transport SRP-dependent Cotranslational Protein Targeting To Membrane Establishment Of Protein Localization Cotranslational Protein Targeting To Membrane Protein Targeting To ER Establishment Of Protein Localization To Endoplasmic Reticulum Intracellular Protein Transport Protein Localization To Endoplasmic Reticulum Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Protein Targeting To Membrane Cellular Nitrogen Compound Metabolic Process Mitotic Nuclear Envelope Disassembly Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Nuclear Envelope Disassembly Nitrogen Compound Metabolic Process Establishment Of Protein Localization To Membrane Nuclear Import Nucleocytoplasmic Transport Nuclear Transport Translational Termination Nuclear-transcribed MRNA Catabolic Process Nuclear Envelope Organization Glucose Transport MRNA Catabolic Process Hexose Transport Translational Elongation Negative Regulation Of Telomere Maintenance Via Telomerase RNA Catabolic Process Cellular Protein Complex Disassembly Protein Localization To Membrane Protein Complex Disassembly Regulation Of Glucose Transport Organelle Organization Translational Initiation Negative Regulation Of Telomere Maintenance	Nucleocytoplasmic Transport Nuclear Transport Viral Process Cytoplasmic Transport MRNA Transport RNA Transport RNA Localization Intracellular Transport Nuclear Import Nucleus Organization Viral Life Cycle NLS-bearing Protein Import Into Nucleus Mitotic Nuclear Envelope Disassembly Nuclear Envelope Disassembly Establishment Of Localization In Cell Protein Transport Protein Localization To Nucleus Cytokine-mediated Signaling Pathway Establishment Of Protein Localization Nuclear Export Cellular Localization Protein Import Into Nucleus Protein Export From Nucleus Intracellular Transport Of Virus Nuclear Envelope Organization Glucose Transport Protein Localization Cellular Response To Cytokine Stimulus Organelle Organization Protein Import Mitotic Cell Cycle Hexose Transport Cellular Protein Localization Viral Transcription Regulation Of Glucose Transport Response To Cytokine RNA Biosynthetic Process Intracellular Protein Transport Cell Cycle Carbohydrate Transport Regulation Of Gluconeogenesis Involved In Cellular Glucose Homeostasis Cellular Response To Organic Substance Protein Localization To Organelle Gene Expression Response To Organic Substance Protein Targeting Nuclear Pore Complex Assembly Pathogenesis Establishment Of Protein Localization To Organelle Ribosomal Protein Import Into Nucleus
Tagcloud ?		apex1 apurine apyrimidine brg1 coherently depict endonuclease escs h2a impalpha4 importin indefinitely macro nono npm1 npr nucleoplasmin octamer pdcd5 pou renew renewal ribonucleoprotein roa2 shotgun snf suz12 sw1 unlimited	barr bblf2 bblf4 betaherpesviruses bglf4 bslf1 cotransfected dilation ebv egress epstein fg gammaherpesviruses gateways import importin lytic mpm nls nlss nucleocapsids nucleocytoplasmic nucleoporins nup153 nups pore reorganization replicating vca
Tagcloud (Difference) ?		apex1 apurine apyrimidine brg1 coherently depict endonuclease escs h2a impalpha4 indefinitely macro nono npm1 npr nucleoplasmin octamer pdcd5 pou renew renewal ribonucleoprotein roa2 shotgun snf suz12 sw1 unlimited	barr bblf2 bblf4 betaherpesviruses bglf4 bslf1 cotransfected dilation ebv egress epstein fg gammaherpesviruses gateways import lytic mpm nls nlss nucleocapsids nucleocytoplasmic nucleoporins nup153 nups pore reorganization replicating vca
Tagcloud (Intersection) ?		importin