IRS1 and PRKCG

  • Number of citations of the paper that reports this interaction (PMID 15364919)
  • 42
  • Data Source:
  • HPRD (in vitro)

IRS1

PRKCG

Gene Name insulin receptor substrate 1 protein kinase C, gamma
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 73 interactors: AKT1 ALK AP3S1 APP ATP2A1 ATP2A2 ATP2A3 BCL2L1 BCR CAV1 CDH1 CHUK CRK CSNK2A1 CSNK2B EGFR ERBB2 FBXO25 FBXW8 FER FES FYN GHR GRB10 GRB14 GRB2 IGF1R IKBKB IL4R INSR JAK1 JAK2 JAK3 MAPK1 MAPK8 MAPK9 MTOR NCK2 NEDD4 NPM1 NTRK1 PDPK1 PHIP PIK3R1 PIK3R2 PIK3R3 PLCG2 PRKCD PRKCG PRKCQ PRKCZ PTK2 PTPN1 PTPN11 PTPRC PTPRF PTPRU RAD51 ROCK1 RPS6KB1 RPTOR SH2B1 SHC1 SIK2 SOCS1 SOCS3 TUB TYK2 UBTF YWHAB YWHAE YWHAG YWHAZ 58 interactors: ADRBK1 AFAP1 ANXA7 APP ARHGEF25 CASR CCHCR1 CD5 CDC42 CHAT CYTH2 DAB2 DDX58 DVL2 EIF4E EPHB1 EXOC5 GABRA1 GABRA4 GFAP GJA1 GJA3 GRIA4 GRIN1 GRIN2B GRIN2D GRM5 GSK3A HABP4 HSPA4 IRS1 ITGB2 MARK4 NFE2L2 NOXA1 NRGN NUMB PA2G4 PARD3 PARD6A PARD6B PDLIM5 PEBP1 PICK1 PNMA1 PPP1R14A RANBP10 RGS2 SCN3A SDC2 STXBP1 TIAM1 TOP2A TRIM5 VTN YWHAB YWHAE YWHAG
Entrez ID 3667 5582
HPRD ID 00943 01502
Ensembl ID ENSG00000169047 ENSG00000126583
Uniprot IDs P35568 F5H5C4 P05129
PDB IDs 1IRS 1K3A 1QQG 2Z8C 2E73 2UZP
Enriched GO Terms of Interacting Partners?
Tagcloud ?
action  adipocytes  biochem  biophys  coimmunoprecipitation  coincided  commun  docking  evidenced  extent  gh  initiating  insulin  involvement  kda  kinase  phosphatidylinositol  phosphorylated  pi  postreceptor  res  ridderstrale  seems  substrate  thereby  tornqvist  tyrosine  wortmannin 
apoc2  atp1a3  bckdha  cgb  cgm2  cyp2a  d19s112  d19s116  d19s117  d19s118  d19s119  d19s19  d19s2  d19s37  d19s50  d19s51  d19s54  d19s55  d19s6  d19s62  d19s63  d19s7  d19s8  d19s9  manb  pepd  psg1  pw39  tnnt1 
Tagcloud (Difference) ?
action  adipocytes  biochem  biophys  coimmunoprecipitation  coincided  commun  docking  evidenced  extent  gh  initiating  insulin  involvement  kda  kinase  phosphatidylinositol  phosphorylated  pi  postreceptor  res  ridderstrale  seems  substrate  thereby  tornqvist  tyrosine  wortmannin 
apoc2  atp1a3  bckdha  cgb  cgm2  cyp2a  d19s112  d19s116  d19s117  d19s118  d19s119  d19s19  d19s2  d19s37  d19s50  d19s51  d19s54  d19s55  d19s6  d19s62  d19s63  d19s7  d19s8  d19s9  manb  pepd  psg1  pw39  tnnt1 
Tagcloud (Intersection) ?