ING1 and NQO1

Number of citations of the paper that reports this interaction (PMID 18388957)
18

Data Source:
HPRD (in vivo)

		ING1	NQO1
Gene Name		inhibitor of growth family, member 1	NAD(P)H dehydrogenase, quinone 1
Image
Gene Ontology Annotations	Cellular Component	Nucleus	Cytoplasm Cytosol Neuronal Cell Body Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Zinc Ion Binding Methylated Histone Binding	NAD(P)H Dehydrogenase (quinone) Activity Cytochrome-b5 Reductase Activity, Acting On NAD(P)H Superoxide Dismutase Activity Protein Binding Identical Protein Binding Poly(A) RNA Binding
	Biological Process	Protein Import Into Nucleus Cell Cycle Negative Regulation Of Cell Proliferation Regulation Of Cell Death Chromatin Modification Negative Regulation Of Cell Growth Positive Regulation Of Transcription, DNA-templated	Regulation Of Cellular Amino Acid Metabolic Process Xenobiotic Metabolic Process Nitric Oxide Biosynthetic Process Synaptic Transmission, Cholinergic Aging Response To Nutrient Response To Toxic Substance Removal Of Superoxide Radicals Response To Estradiol Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Catalytic Activity Positive Regulation Of Neuron Apoptotic Process Small Molecule Metabolic Process Response To Ethanol Oxidation-reduction Process
Pathways			Regulation of ornithine decarboxylase (ODC) Metabolism of amino acids and derivatives
Drugs			Menadione Dicumarol Duroquinone 3-Hydroxymethyl-5-Aziridinyl-1methyl-2-[1h-Indole-4,7-Dione]-Propanol 5-Methoxy-1,2-Dimethyl-3-(4-Nitrophenoxymethyl)Indole-4,7-Dione Cibacron Blue Flavin-Adenine Dinucleotide 5-Methoxy-1,2-Dimethyl-3-(Phenoxymethyl)Indole-4,7-Dione 2,5-Diaziridin-1-Yl-3-(Hydroxymethyl)-6-Methylcyclohexa-2,5-Diene-1,4-Dione Bishydroxy[2h-1-Benzopyran-2-One,1,2-Benzopyrone] 3-(HYDROXYMETHYL)-1-METHYL-5-(2-METHYLAZIRIDIN-1-YL)-2-PHENYL-1H-INDOLE-4,7-DIONE
Diseases
GWAS
Protein-Protein Interactions		29 interactors: BRMS1 BRMS1L COPS2 DMAP1 EP300 ESR1 HDAC1 HDAC2 HIST2H3A HIST2H3C HIST4H4 KAT2B LINC00152 MRGBP NQO1 PCNA RBBP4 RBBP7 RBP1 SAP30 SFN SIN3A TP53 YWHAB YWHAE YWHAG YWHAH YWHAQ YWHAZ	5 interactors: DNAJB1 HSPA1A ING1 STUB1 TP53
Entrez ID		3621	1728
HPRD ID		03337	00518
Ensembl ID		ENSG00000153487	ENSG00000181019
Uniprot IDs		Q9UK53	B4DLR8 P15559
PDB IDs		2QIC	1D4A 1DXO 1GG5 1H66 1H69 1KBO 1KBQ 1QBG 2F1O 3JSX
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Negative Regulation Of Gene Expression Chromatin Organization Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Negative Regulation Of Cellular Metabolic Process Chromosome Organization Negative Regulation Of Gene Expression, Epigenetic Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression, Epigenetic Chromatin Modification Positive Regulation Of Mitochondrion Organization Negative Regulation Of Biosynthetic Process Regulation Of Mitochondrion Organization Organelle Organization Regulation Of Transcription, DNA-templated Regulation Of Nitrogen Compound Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Intrinsic Apoptotic Signaling Pathway Regulation Of Metabolic Process Regulation Of RNA Metabolic Process Gene Expression Regulation Of Gene Expression Positive Regulation Of Intracellular Transport Histone Modification Chromatin Remodeling Positive Regulation Of Apoptotic Signaling Pathway Cellular Nitrogen Compound Metabolic Process Apoptotic Signaling Pathway Regulation Of Apoptotic Process Regulation Of Transcription From RNA Polymerase II Promoter Nucleobase-containing Compound Metabolic Process Regulation Of Cell Death Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA Metabolic Process Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Nitrogen Compound Metabolic Process RNA Biosynthetic Process Positive Regulation Of Cell Death Regulation Of Intracellular Transport Regulation Of Cellular Process Histone Deacetylation Protein Deacetylation	Negative Regulation Of Inclusion Body Assembly Response To Unfolded Protein Negative Regulation Of Cell Growth Regulation Of Cellular Component Organization Regulation Of Inclusion Body Assembly Protein Refolding Negative Regulation Of Growth Regulation Of Cellular Response To Heat Regulation Of Cell Growth Cellular Response To Heat Cellular Response To Stress Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Growth Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Cellular Response To Growth Factor Stimulus ER-nucleus Signaling Pathway Negative Regulation Of Cell Proliferation Response To Heat Protein Import Into Nucleus Nuclear Import Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Macromitophagy Positive Regulation Of Chaperone-mediated Protein Complex Assembly Cellular Heat Acclimation Oligodendrocyte Apoptotic Process Protein Import Response To Endoplasmic Reticulum Stress Protein Localization To Nucleus Positive Regulation Of Protein Complex Assembly Regulation Of Cellular Response To Growth Factor Stimulus Cellular Response To Transforming Growth Factor Beta Stimulus Response To Organic Substance Negative Regulation Of Helicase Activity Response To Transforming Growth Factor Beta Response To Temperature Stimulus Cellular Response To Oxidative Stress Regulation Of Protein Ubiquitination Negative Regulation Of Signal Transduction Response To Abiotic Stimulus Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Signaling Positive Regulation Of Cell Aging Positive Regulation Of Thymocyte Apoptotic Process Chaperone Cofactor-dependent Protein Refolding Nucleocytoplasmic Transport Nuclear Transport Ubiquitin-dependent SMAD Protein Catabolic Process Mitochondrial DNA Repair Protein Folding
Tagcloud ?		13q33 bptf col4a1 col4a2 d13s1315 d13s158 d13s278 d13s285 d13s779 d13s796 e2f ets flanking genomatix heterozygosity hif1 loh matinspector microdeletion nrsf rel softwares sox sox1 tfsearch tsg tsgs warrants	absorbance antioxidants assayed benzyl centrifugal edible fcpc fractionate hepa1c1c7 inducer isothiocyanate itc itcs leaves moringa nad nutritious oleifera orac oxidoreductase partition polyphenol polyphenols preparatory quinone rhamnosyloxy sf sulforaphane tropical
Tagcloud (Difference) ?		13q33 bptf col4a1 col4a2 d13s1315 d13s158 d13s278 d13s285 d13s779 d13s796 e2f ets flanking genomatix heterozygosity hif1 loh matinspector microdeletion nrsf rel softwares sox sox1 tfsearch tsg tsgs warrants	absorbance antioxidants assayed benzyl centrifugal edible fcpc fractionate hepa1c1c7 inducer isothiocyanate itc itcs leaves moringa nad nutritious oleifera orac oxidoreductase partition polyphenol polyphenols preparatory quinone rhamnosyloxy sf sulforaphane tropical
Tagcloud (Intersection) ?