APOD and POLR2M

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		APOD	POLR2M
Gene Name		apolipoprotein D	polymerase (RNA) II (DNA directed) polypeptide M
Image
Gene Ontology Annotations	Cellular Component	Extracellular Region Extracellular Space Endoplasmic Reticulum Cytosolic Ribosome Dendrite Neuronal Cell Body Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome	Nuclear Envelope DNA-directed RNA Polymerase II, Holoenzyme Neuronal Cell Body
	Molecular Function	Lipid Transporter Activity Protein Binding Cholesterol Binding	DNA-directed RNA Polymerase Activity
	Biological Process	Response To Reactive Oxygen Species Angiogenesis Glucose Metabolic Process Lipid Metabolic Process Lipid Transport Brain Development Aging Negative Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Peripheral Nervous System Axon Regeneration Tissue Regeneration Negative Regulation Of Protein Import Into Nucleus Response To Drug Negative Regulation Of Smooth Muscle Cell Proliferation Response To Axon Injury Negative Regulation Of Focal Adhesion Assembly Negative Regulation Of Lipoprotein Lipid Oxidation Negative Regulation Of Monocyte Chemotactic Protein-1 Production Negative Regulation Of Cytokine Production Involved In Inflammatory Response Negative Regulation Of Smooth Muscle Cell-matrix Adhesion Negative Regulation Of T Cell Migration	RNA Biosynthetic Process Maintenance Of ER Location
Pathways		Transport of vitamins, nucleosides, and related molecules SLC-mediated transmembrane transport Transport of fatty acids Orphan transporters
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: APOA2 LEPR POLR2M SHBG VAPA	19 interactors: AHSP ANKHD1 APOD CEBPG DGKZ HIGD1B KIAA1377 MYO3A MYO9A NEDD4 PSMC2 RBM4B RPL7A SCMH1 SIVA1 THAP1 UQCRQ WDR89 ZNF410
Entrez ID		347	81488
HPRD ID		00134	07575
Ensembl ID		ENSG00000189058	ENSG00000255529
Uniprot IDs		P05090	P0CAP1 P0CAP2 Q6EEV4
PDB IDs		2APD 2HZQ 2HZR	2KXS
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Growth Hormone Receptor Signaling Pathway Maintenance Of ER Location Primary Spermatocyte Growth Negative Regulation Of Cholesterol Transporter Activity Cholesterol Metabolic Process Sterol Metabolic Process Negative Regulation By Host Of Viral Genome Replication Positive Regulation By Host Of Viral Release From Host Cell Regulation Of Cholesterol Transporter Activity Negative Regulation Of Cholesterol Import Negative Regulation Of Very-low-density Lipoprotein Particle Remodeling Endoplasmic Reticulum Localization Regulation Of Cholesterol Import Regulation Of Growth Hormone Receptor Signaling Pathway Positive Regulation By Host Of Viral Genome Replication Positive Regulation By Host Of Viral Process Diacylglycerol Catabolic Process Steroid Metabolic Process High-density Lipoprotein Particle Clearance Regulation Of Intestinal Cholesterol Absorption Protein Oxidation Lipid Metabolic Process Positive Regulation Of Viral Release From Host Cell Negative Regulation Of Cytokine Secretion Involved In Immune Response Positive Regulation Of Interleukin-8 Biosynthetic Process High-density Lipoprotein Particle Assembly Negative Regulation Of Protein Localization To Cell Surface Positive Regulation Of Cholesterol Esterification Peptidyl-methionine Modification Alcohol Metabolic Process Regulation Of Cholesterol Esterification Negative Regulation Of Cholesterol Transport Triglyceride-rich Lipoprotein Particle Remodeling Negative Regulation Of Gluconeogenesis Phospholipid Efflux Regulation Of Interleukin-8 Biosynthetic Process Low-density Lipoprotein Particle Remodeling Negative Regulation Of Hydrolase Activity Regulation Of Cytokine Secretion Involved In Immune Response High-density Lipoprotein Particle Remodeling Protein-lipid Complex Assembly Negative Regulation Of Lipase Activity Reverse Cholesterol Transport Diacylglycerol Metabolic Process Regulation Of Protein Localization To Cell Surface Positive Regulation Of Viral Genome Replication COPII-coated Vesicle Budding Regulation Of Viral Release From Host Cell Negative Regulation Of JAK-STAT Cascade Negative Regulation Of Lipid Transport	Viral Process Regulation Of Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Negative Regulation Of T Cell Migration Negative Regulation Of Lipoprotein Lipid Oxidation Transmission Of Virus Development Involved In Symbiotic Interaction Mitotic G1 DNA Damage Checkpoint Mitotic G1/S Transition Checkpoint G1 DNA Damage Checkpoint Negative Regulation Of Smooth Muscle Cell-matrix Adhesion Subthalamus Development Negative Regulation Of Cytokine Production Involved In Inflammatory Response Regulation Of Lipoprotein Lipid Oxidation Mitotic DNA Damage Checkpoint Regulation Of Smooth Muscle Cell-matrix Adhesion Negative Regulation Of Monocyte Chemotactic Protein-1 Production Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Mitotic DNA Integrity Checkpoint Interaction With Host Regulation Of Mitotic Cell Cycle Negative Regulation Of Lymphocyte Migration Regulation Of Intracellular Transport Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition Progesterone Receptor Signaling Pathway Developmental Process
Tagcloud ?		a4 antitrypsin apoa apoc apof apoh apoj apol apolipoproteins apom atherogenic carry chd convincingly delipidation dense differs fibrinogen ldl lysosome originate paraoxonase prenylcysteine proteome sdldl strengthens subfractions transthyretin vldl
Tagcloud (Difference) ?		a4 antitrypsin apoa apoc apof apoh apoj apol apolipoproteins apom atherogenic carry chd convincingly delipidation dense differs fibrinogen ldl lysosome originate paraoxonase prenylcysteine proteome sdldl strengthens subfractions transthyretin vldl
Tagcloud (Intersection) ?