IDH3A and IDH3B

Number of citations of the paper that reports this interaction (PMID 10601238)
7

Data Source:
HPRD (in vivo, in vitro)

		IDH3A	IDH3B
Gene Name		isocitrate dehydrogenase 3 (NAD+) alpha	isocitrate dehydrogenase 3 (NAD+) beta
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Mitochondrion Mitochondrial Matrix	Nucleus Mitochondrion Mitochondrial Matrix
	Molecular Function	Magnesium Ion Binding Isocitrate Dehydrogenase (NAD+) Activity NAD Binding	Magnesium Ion Binding Isocitrate Dehydrogenase (NAD+) Activity Electron Carrier Activity NAD Binding
	Biological Process	Carbohydrate Metabolic Process Tricarboxylic Acid Cycle Cellular Metabolic Process Small Molecule Metabolic Process	Tricarboxylic Acid Cycle Isocitrate Metabolic Process 2-oxoglutarate Metabolic Process NADH Metabolic Process Cellular Metabolic Process Small Molecule Metabolic Process
Pathways		Pyruvate metabolism and Citric Acid (TCA) cycle The citric acid (TCA) cycle and respiratory electron transport Citric acid cycle (TCA cycle)	Pyruvate metabolism and Citric Acid (TCA) cycle The citric acid (TCA) cycle and respiratory electron transport Citric acid cycle (TCA cycle)
Drugs		NADH	NADH
Diseases
GWAS
Protein-Protein Interactions		5 interactors: IDH3B IDH3G MBNL1 RAB4A SUMO4	6 interactors: ATXN2 IDH3A IDH3G MAPK6 PRMT1 RAB35
Entrez ID		3419	3420
HPRD ID		03094	05163
Ensembl ID			ENSG00000101365
Uniprot IDs		B4DJB4 B7Z9J8 H0YL72 P50213	O43837
PDB IDs
Enriched GO Terms of Interacting Partners?		Isocitrate Metabolic Process Tricarboxylic Acid Cycle Citrate Metabolic Process Tricarboxylic Acid Metabolic Process Aerobic Respiration Cellular Respiration Energy Derivation By Oxidation Of Organic Compounds Alternative MRNA Splicing, Via Spliceosome Generation Of Precursor Metabolites And Energy 2-oxoglutarate Metabolic Process NADH Metabolic Process	Tricarboxylic Acid Cycle Citrate Metabolic Process Tricarboxylic Acid Metabolic Process Aerobic Respiration Cellular Respiration Neuron Projection Development Negative Regulation Of Megakaryocyte Differentiation Neuron Development Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine Plasma Membrane To Endosome Transport Neuron Differentiation Cell Projection Organization Isocitrate Metabolic Process Energy Derivation By Oxidation Of Organic Compounds Negative Regulation Of Hematopoietic Progenitor Cell Differentiation Protein Localization To Endosome Negative Regulation Of Receptor Internalization Cytoplasmic MRNA Processing Body Assembly Peptidyl-arginine N-methylation Histone H4-R3 Methylation Cerebellar Purkinje Cell Differentiation Stress Granule Assembly Cerebellar Purkinje Cell Layer Morphogenesis Generation Of Precursor Metabolites And Energy Histone Arginine Methylation Peptidyl-arginine Methylation Regulation Of Megakaryocyte Differentiation Generation Of Neurons Negative Regulation Of Receptor-mediated Endocytosis Negative Regulation Of Multicellular Organism Growth Neurogenesis Endocytic Recycling Cerebellar Cortex Formation Cellular Response To Nerve Growth Factor Stimulus Cell Development Cell Differentiation In Hindbrain Regulation Of Hematopoietic Progenitor Cell Differentiation Regulation Of Receptor Internalization Cerebellar Purkinje Cell Layer Development Cerebellar Cortex Morphogenesis
Tagcloud ?		aldoa atp5a1 atp5b atp5h cox5a cox5b dlst eno1 etc fbp1 glycolysis idh2 nduf2 ndufa5 ndufb10 ndufs1 ogdh organelles oxphos pgk1 rab sdha spatio suclag2 taldo1 tca uqcrh uqrb uqrc2
Tagcloud (Difference) ?		aldoa atp5a1 atp5b atp5h cox5a cox5b dlst eno1 etc fbp1 glycolysis idh2 nduf2 ndufa5 ndufb10 ndufs1 ogdh organelles oxphos pgk1 rab sdha spatio suclag2 taldo1 tca uqcrh uqrb uqrc2
Tagcloud (Intersection) ?