APOBEC1 and SYNCRIP

Number of citations of the paper that reports this interaction (PMID 11352648)
4

Data Source:
BioGRID (pull down)

		APOBEC1	SYNCRIP
Gene Name		apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1	synaptotagmin binding, cytoplasmic RNA interacting protein
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm	Nucleus Nucleoplasm Endoplasmic Reticulum Membrane Ribonucleoprotein Complex CRD-mediated MRNA Stability Complex Catalytic Step 2 Spliceosome Histone Pre-mRNA 3'end Processing Complex GAIT Complex
	Molecular Function	RNA Binding Cytidine Deaminase Activity Protein Binding Zinc Ion Binding AU-rich Element Binding	Nucleotide Binding RNA Binding Protein Binding Poly(A) Binding Poly(A) RNA Binding
	Biological Process	RNA Processing MRNA Processing Lipid Metabolic Process Response To Osmotic Stress Cytidine Deamination Response To Zinc Ion Response To Gamma Radiation Gene Expression Cytidine To Uridine Editing MRNA Modification Cellular Response To Insulin Stimulus Regulation Of Cell Proliferation Lipoprotein Biosynthetic Process Response To Drug Lipoprotein Transport Response To Ethanol MRNA Stabilization Response To Calcium Ion Defense Response To Virus DNA Demethylation Negative Regulation Of Methylation-dependent Chromatin Silencing	MRNA Splicing, Via Spliceosome Osteoblast Differentiation RNA Processing RNA Splicing Viral Process Negative Regulation Of Translation CRD-mediated MRNA Stabilization Cellular Response To Interferon-gamma
Pathways		mRNA Editing: C to U Conversion mRNA Editing Formation of the Editosome
Drugs
Diseases
GWAS
Protein-Protein Interactions		7 interactors: A1CF APOBEC2 BAG4 CELF2 DNAJB11 KPNA2 SYNCRIP	31 interactors: A1CF APOBEC1 APP CSDE1 EPRS GRB2 HABP4 HMGA1 HMGA2 HNRNPD HNRNPK IL7R INSR IVNS1ABP KLHL3 NUPR1 PABPC1 PCSK7 PLCG1 PRMT1 PRMT8 PTPN11 SMN1 SYT1 SYT11 SYT2 SYT3 SYT4 SYT7 SYT8 SYT9
Entrez ID		339	10492
HPRD ID		02531	06734
Ensembl ID		ENSG00000111701	ENSG00000135316
Uniprot IDs		P41238	B7Z645 O60506 Q59GL1
PDB IDs			2DGU
Enriched GO Terms of Interacting Partners?		MRNA Modification MRNA Metabolic Process MRNA Processing RNA Modification RNA Processing Negative Regulation Of MRNA Modification Negative Regulation Of Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase Activity Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Response To Cytokine Stimulus Cellular Nitrogen Compound Metabolic Process Cytidine To Uridine Editing RNA Metabolic Process Response To Cytokine Nitrogen Compound Metabolic Process Cellular Response To Organic Substance CRD-mediated MRNA Stabilization MRNA Localization Resulting In Posttranscriptional Regulation Of Gene Expression Base Conversion Or Substitution Editing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Cytidine Deamination Cellular Metabolic Process Protein Folding Intracellular MRNA Localization Positive Regulation Of Fibroblast Migration Response To Organic Substance RNA Splicing Regulation Of Metabolic Process DNA Demethylation Pyrimidine Nucleoside Catabolic Process NLS-bearing Protein Import Into Nucleus Ruffle Assembly Posttranscriptional Regulation Of Gene Expression Cellular Response To Epidermal Growth Factor Stimulus MRNA Stabilization Response To Epidermal Growth Factor Regulation Of Fibroblast Migration Viral Process Gene Expression Ruffle Organization MRNA Splice Site Selection Positive Regulation Of Stress Fiber Assembly	Exocytosis MRNA Metabolic Process RNA Processing Regulation Of Calcium Ion-dependent Exocytosis Positive Regulation Of Calcium Ion-dependent Exocytosis MRNA Processing Cytidine To Uridine Editing Oncogene-induced Cell Senescence Secretion By Cell Positive Regulation Of Transport Senescence-associated Heterochromatin Focus Assembly Regulation Of Vesicle-mediated Transport Positive Regulation Of Cellular Senescence Regulation Of Vesicle Fusion Secretion Regulation Of Secretion RNA Metabolic Process Aromatic Compound Catabolic Process Posttranscriptional Regulation Of Gene Expression Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine Negative Regulation Of Chromatin Silencing Base Conversion Or Substitution Editing Regulation Of Cellular Localization Regulation Of Exocytosis Positive Regulation Of Cellular Metabolic Process Regulation Of MRNA Stability Regulation Of RNA Stability Positive Regulation Of Cell Aging Vesicle-mediated Transport Viral Process Positive Regulation Of Exocytosis RNA Splicing Regulation Of Growth Hormone Secretion Wound Healing Regulation Of Gene Expression Heterochromatin Assembly Positive Regulation Of Protein Metabolic Process Peptidyl-arginine N-methylation Histone H4-R3 Methylation Positive Regulation Of Metabolic Process Cellular Response To Insulin Stimulus Gene Expression Regulation Of Peptide Hormone Secretion Heterochromatin Organization Blood Coagulation Reproductive Process Hemostasis MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Response To Wounding
Tagcloud ?		aid apolipoprotein atherosclerosis atherosclerotic causal coincident crosses dissecting dyslipidemia editing founder genotyped hampers haplotypes hfca hidden inbred informative mapping markov multiparental outbred qtl reconstructed renders trait triglyceride triglycerides	autonomy back bmp bottom connections correct explained genetically glass highlight influences maintaining modulates morphogenic motoneuron output partly plasticity postsynaptic presynaptic probability proper retrograde signals synapse synaptic transmission unexpected vesicle
Tagcloud (Difference) ?		aid apolipoprotein atherosclerosis atherosclerotic causal coincident crosses dissecting dyslipidemia editing founder genotyped hampers haplotypes hfca hidden inbred informative mapping markov multiparental outbred qtl reconstructed renders trait triglyceride triglycerides	autonomy back bmp bottom connections correct explained genetically glass highlight influences maintaining modulates morphogenic motoneuron output partly plasticity postsynaptic presynaptic probability proper retrograde signals synapse synaptic transmission unexpected vesicle
Tagcloud (Intersection) ?