HUS1 and DNAJC7

Number of citations of the paper that reports this interaction (PMID 11573955)
1

Data Source:
HPRD (in vivo, in vitro)

		HUS1	DNAJC7
Gene Name		HUS1 checkpoint homolog (S. pombe)	DnaJ (Hsp40) homolog, subfamily C, member 7
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Checkpoint Clamp Complex	Nucleoplasm Cytoplasm Cytoskeleton Membrane Extracellular Vesicular Exosome
	Molecular Function	Protein Binding	Protein Binding Heat Shock Protein Binding
	Biological Process	DNA Damage Checkpoint Double-strand Break Repair Via Homologous Recombination Regulation Of Protein Phosphorylation DNA Replication DNA Repair Protein Phosphorylation Cellular Response To DNA Damage Stimulus Mitotic Cell Cycle Checkpoint Negative Regulation Of DNA Replication Response To UV Embryo Development Cellular Response To Ionizing Radiation	Protein Folding Chaperone Cofactor-dependent Protein Refolding
Pathways		G2/M Checkpoints Activation of ATR in response to replication stress Cell Cycle Checkpoints
Drugs
Diseases
GWAS
Protein-Protein Interactions		16 interactors: CD200 COPS5 DNAJC7 HDAC1 HUS1B MSH2 MSH3 MSH6 PCNA RAD1 RAD17 RAD9A RAD9B RPA1 RPA2 YWHAQ	14 interactors: DISC1 HSP90AA1 HSPA1A HSPA8 HUS1 MKNK1 NF1 RAD1 RAD9A SMAD2 SMAD9 SMURF1 TP53 UBE4B
Entrez ID		3364	7266
HPRD ID		04787	07046
Ensembl ID		ENSG00000136273	ENSG00000168259
Uniprot IDs		A4D2F2 O60921	Q99615
PDB IDs		3A1J 3G65 3GGR
Enriched GO Terms of Interacting Partners?		DNA Repair Cellular Response To DNA Damage Stimulus Mismatch Repair Cell Cycle DNA Damage Checkpoint Cell Cycle Process DNA Metabolic Process Cell Cycle Checkpoint Cellular Response To Stress Meiotic Mismatch Repair DNA Replication Positive Regulation Of Helicase Activity DNA Recombination Response To Stress Regulation Of DNA Recombination Nucleobase-containing Compound Metabolic Process Nucleotide-excision Repair, DNA Gap Filling Meiotic Cell Cycle Negative Regulation Of DNA Recombination Mitotic Cell Cycle Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Telomere Maintenance Via Semi-conservative Replication Negative Regulation Of Cell Cycle Negative Regulation Of DNA Metabolic Process Nuclear DNA Replication Telomere Maintenance Via Recombination Cellular Nitrogen Compound Metabolic Process Mitotic Recombination DNA Strand Elongation Involved In DNA Replication DNA Strand Elongation Regulation Of Cell Cycle Telomere Maintenance Via Telomere Lengthening Somatic Recombination Of Immunoglobulin Gene Segments Nitrogen Compound Metabolic Process Somatic Diversification Of Immunoglobulins DNA Catabolic Process Maintenance Of DNA Repeat Elements Transcription-coupled Nucleotide-excision Repair Mitotic Cell Cycle Process Mitotic Cell Cycle Checkpoint DNA Recombinase Assembly Meiotic Nuclear Division Immunoglobulin Production Base-excision Repair Negative Regulation Of Mitotic Cell Cycle Cellular Response To Stimulus Telomere Maintenance Intra-S DNA Damage Checkpoint DNA Replication Checkpoint	Response To Abiotic Stimulus Cellular Response To Stimulus Cellular Response To Ionizing Radiation Response To Radiation Protein Refolding Response To Stimulus Regulation Of Cellular Response To Heat Cellular Response To Radiation Transforming Growth Factor Beta Receptor Signaling Pathway Response To Ionizing Radiation DNA Damage Checkpoint Response To Stress Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta Regulation Of Neuroblast Proliferation Enzyme Linked Receptor Protein Signaling Pathway Cellular Response To Heat Cell Cycle Checkpoint Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Cellular Response To Stress Cellular Response To Growth Factor Stimulus Response To Growth Factor Response To Organic Substance Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Neural Precursor Cell Proliferation Negative Regulation Of Cellular Response To Growth Factor Stimulus Response To Light Stimulus Regulation Of Stem Cell Proliferation Response To Heat Apoptotic Signaling Pathway Brain Development Response To UV Anatomical Structure Development Response To Unfolded Protein Head Development Regulation Of Cellular Process Cellular Macromolecule Catabolic Process Negative Regulation Of Neuroblast Proliferation Mitotic Cell Cycle Checkpoint Negative Regulation Of Cell Cycle Cell Surface Receptor Signaling Pathway Regulation Of Cell Cycle Cellular Metabolic Process Nervous System Development Regulation Of Cell Differentiation Regulation Of Cellular Response To Growth Factor Stimulus Negative Regulation Of Stem Cell Proliferation Developmental Process
Tagcloud ?		abrogates atr bona checkpoint chk1 clamp claspin damaging extensively fide heterotetrameric impacting irradiation lac laco lacr lastly localizes onto orphan portion rad1 rad9 repeats repressor rhino tethering topbp1 uv
Tagcloud (Difference) ?		abrogates atr bona checkpoint chk1 clamp claspin damaging extensively fide heterotetrameric impacting irradiation lac laco lacr lastly localizes onto orphan portion rad1 rad9 repeats repressor rhino tethering topbp1 uv
Tagcloud (Intersection) ?