HSPB2 and CRYGC

Number of citations of the paper that reports this interaction (PMID 12601044)
21

Data Source:
BioGRID (two hybrid)

		HSPB2	CRYGC
Gene Name		heat shock 27kDa protein 2	crystallin, gamma C
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Cytosol	Nucleus Cytoplasm
	Molecular Function	Protein Binding Enzyme Activator Activity	Structural Constituent Of Eye Lens Protein Binding
	Biological Process	Response To Unfolded Protein Positive Regulation Of Catalytic Activity	Visual Perception Camera-type Eye Development
Pathways
Drugs
Diseases
GWAS			Attention deficit hyperactivity disorder ( 18839057)
Protein-Protein Interactions		12 interactors: CLK4 CRYAA CRYAB CRYGC DMPK HNRNPD HSPB3 HSPB8 MAPKAPK5 RPS6KA5 SNCA UBL5	7 interactors: CRYAA CRYAB CRYBB2 CRYGD HSPB1 HSPB2 MIP
Entrez ID		3316	1420
HPRD ID		03712	00435
Ensembl ID			ENSG00000163254
Uniprot IDs		A8KAH6 Q16082	P07315
PDB IDs			1LFE
Enriched GO Terms of Interacting Partners?		Phosphorylation MAPK Cascade Regulation Of Histone Acetylation Signal Transduction By Phosphorylation Aging Histone H2A-S1 Phosphorylation Negative Regulation Of Thrombin Receptor Signaling Pathway Positive Regulation Of Hydrogen Peroxide Catabolic Process Positive Regulation Of Glutathione Peroxidase Activity Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Norepinephrine Uptake Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Response To Interleukin-1 Negative Regulation Of Transport Negative Regulation Of Mitochondrial Electron Transport, NADH To Ubiquinone Regulation Of Intracellular Transport Posttranscriptional Regulation Of Gene Expression Phosphate-containing Compound Metabolic Process Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Negative Regulation Of Dopamine Metabolic Process Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Serotonin Uptake Negative Regulation Of Cellular Respiration Negative Regulation Of Intracellular Transport Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process Regulation Of Histone Modification Histone H3-S10 Phosphorylation Negative Regulation Of Synaptic Transmission, Dopaminergic Negative Regulation Of Oxidative Phosphorylation Positive Regulation Of Histone Phosphorylation Positive Regulation Of Protein Metabolic Process Regulation Of Reactive Oxygen Species Metabolic Process Regulation Of Protein Metabolic Process Response To Iron(II) Ion Cellular Response To Copper Ion Circadian Regulation Of Translation Protein Phosphorylation Visual Perception Sensory Perception Of Light Stimulus Regulation Of Synaptic Vesicle Recycling Tubulin Complex Assembly Histone H3-S28 Phosphorylation Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Cysteine-type Endopeptidase Activity Regulation Of Chromosome Organization Regulation Of Dopamine Uptake Involved In Synaptic Transmission Positive Regulation Of Protein Phosphorylation	Visual Perception Sensory Perception Of Light Stimulus Camera-type Eye Development Lens Development In Camera-type Eye Eye Development Sensory Organ Development Sensory Perception Neurological System Process Negative Regulation Of Intracellular Transport Response To Stimulus Response To Unfolded Protein Positive Regulation Of Endothelial Cell Chemotaxis By VEGF-activated Vascular Endothelial Growth Factor Receptor Signaling Pathway Response To Reactive Oxygen Species Positive Regulation Of Cell Migration By Vascular Endothelial Growth Factor Signaling Pathway Canalicular Bile Acid Transport Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Protein Processing Involved In Protein Targeting To Mitochondrion Negative Regulation Of Cell Death Tubulin Complex Assembly Protein Homooligomerization Positive Regulation Of Endothelial Cell Chemotaxis Bile Acid Secretion Glycerol Transport Positive Regulation Of Tumor Necrosis Factor Biosynthetic Process Mitochondrial Protein Processing Polyol Transport Cellular Water Homeostasis Negative Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Regulation Of Tumor Necrosis Factor Biosynthetic Process Negative Regulation Of Transport Positive Regulation Of Blood Vessel Endothelial Cell Migration Apoptotic Process Involved In Morphogenesis Cellular Response To Gamma Radiation Response To Oxidative Stress Organ Development Protein Oligomerization Regulation Of Apoptotic Process Regulation Of Intracellular Transport Apoptotic Process Involved In Development Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Regulation Of Cell Death Vascular Endothelial Growth Factor Signaling Pathway Negative Regulation Of Oxidative Stress-induced Cell Death Positive Regulation Of Interleukin-1 Beta Production Positive Regulation Of Interleukin-1 Production Bile Acid And Bile Salt Transport Cell Volume Homeostasis
Tagcloud ?		apg1 forelimb forelimbs grp94 hindlimb hindlimbs hsp10 hsp105 hsp110 hsp20 hsp22 hsp25 hsp47 hsp60 hspa12a hspa12b hspa13 hspa14 hspa1l hspb10 hspb3 hspb4 hspb7 hspb9 hsps oligodactylic performs phocomelic trap1	coherence cryba1 cryba2 cryba4 crybb1 crybb2 crybb3 crystallin degenerative erg grafted holds intravitreal iodate lentivirally migrated millions msc mscs neurotrophin nt perception photoreceptors prosurvival retina retinal retinopathies rpe survived
Tagcloud (Difference) ?		apg1 forelimb forelimbs grp94 hindlimb hindlimbs hsp10 hsp105 hsp110 hsp20 hsp22 hsp25 hsp47 hsp60 hspa12a hspa12b hspa13 hspa14 hspa1l hspb10 hspb3 hspb4 hspb7 hspb9 hsps oligodactylic performs phocomelic trap1	coherence cryba1 cryba2 cryba4 crybb1 crybb2 crybb3 crystallin degenerative erg grafted holds intravitreal iodate lentivirally migrated millions msc mscs neurotrophin nt perception photoreceptors prosurvival retina retinal retinopathies rpe survived
Tagcloud (Intersection) ?